“When to Nuss? patient age as a risk factor for complications of minimally invasive repair of pectus excavatum: a systematic review and meta-analysis”

2022 ◽  
Author(s):  
Arielle C. Coughlin ◽  
Sofia Ahsanuddin ◽  
Dani Inglesby ◽  
Conner Fox ◽  
Hope Xu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Minimally Invasive ◽  
Pectus Excavatum ◽  
Meta Analysis ◽  
Patient Age ◽  
Patient Âgé

scholarly journals Kisspeptin Levels in Girls with Precocious Puberty: A Systematic Review and Meta-Analysis

2021 ◽  
pp. 1-10
Author(s):  
Rafael Guerra Cintra ◽  
Rubens Wajnsztejn ◽  
Camila Martins Trevisan ◽  
Victor Zaia ◽  
Antonio Simone Laganà ◽  
...  
Keyword(s):  
Systematic Review ◽  
Precocious Puberty ◽  
Meta Analysis ◽  
Reproductive Function ◽  
Cochrane Library ◽  
Consistent Difference ◽  
Patient Age ◽  
Patient Âgé ◽  
Group A ◽  
The Cochrane Library

<b><i>Background/Aims:</i></b> Kisspeptin (KP) is a key player in the regulation of the release of gonadotropin-releasing hormone (GnRH), which increases the secretion of gonadotropin during puberty to establish reproductive function and regulate the hypothalamic-pituitary-gonadal axis. Premature activation of GnRH secretion leads to idiopathic/central gonadotropin-dependent precocious puberty (CPP). We aimed to compare the blood KP concentrations in girls with CPP and healthy controls. <b><i>Methods:</i></b> A systematic review and meta-analysis was performed. We searched MEDLINE, EMBASE, The Cochrane Library, and SciELO. Random-effects model and standardized mean difference (SMD) were used. Heterogeneity was assessed through <i>I</i><sup>2</sup>. Meta-regression considered patient age, KP fraction, and analytical method for KP measurement. <b><i>Results:</i></b> The 11 studies included comprised 316 CPP patients and 251 controls. Higher KP levels in the CPP group were found (SMD 1.53; CI 95% = 0.56–2.51). Subgroup analysis revealed association with patient age (<i>p</i> = 0.048), indicating a positive correlation between elevation in KP concentration and age in CPP group. A group of patients with precocious thelarche (PT) from 5 of the included studies comprising 121 patients showed higher levels of KP (1.10; −0.25–2.45: CI 95%) and high heterogeneity (<i>I</i><sup>2</sup> = 91%). The CPP/PT ratio for KP level indicates KP 36% higher on CPP than PT patients. <b><i>Conclusions:</i></b> A consistent difference in KP levels between girls with CPP and controls was identified. While there are important limitations in KP assays which argue against its use as a diagnostic tool, the KP levels in CPP versus control and PT children are consistent with the predicted mechanisms and pathophysiology of CPP.

scholarly journals Epidural analgesia versus intravenous patient-controlled analgesia following minimally invasive pectus excavatum repair: a systematic review and meta-analysis

2014 ◽  
Vol 49 (5) ◽  
pp. 798-806 ◽  
Author(s):  
Andrea M. Stroud ◽  
Darena D. Tulanont ◽  
Thomasena E. Coates ◽  
Philip P. Goodney ◽  
Daniel P. Croitoru
Keyword(s):  
Systematic Review ◽  
Minimally Invasive ◽  
Epidural Analgesia ◽  
Pectus Excavatum ◽  
Meta Analysis ◽  
Patient Controlled Analgesia

Hemmkörperentwicklung bei Hämophilie-Patienten nach Präparate wechsel

2012 ◽  
Vol 32 (S 01) ◽  
pp. S39-S42 ◽  
Author(s):  
S. Kocher ◽  
G. Asmelash ◽  
V. Makki ◽  
S. Müller ◽  
S. Krekeler ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Observational Study ◽  
Retrospective Observational Study ◽  
Frequent Change ◽  
Patient Age ◽  
Treatment Regimens ◽  
Patient Âgé ◽  
The Relationship ◽  
Observation Period

SummaryThe retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. Results: During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn’t lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.

Minimally Invasive Pancreaticoduodenectomy: What is the Best “Choice”? A Systematic Review and Network Meta-analysis of Non-randomized Comparative Studies

2017 ◽  
Vol 42 (3) ◽  
pp. 788-805 ◽  
Author(s):  
Claudio Ricci ◽  
Riccardo Casadei ◽  
Giovanni Taffurelli ◽  
Carlo Alberto Pacilio ◽  
Marco Ricciardiello ◽  
...  
Keyword(s):  
Systematic Review ◽  
Minimally Invasive ◽  
Comparative Studies ◽  
Meta Analysis
Sign in / Sign up

Export Citation Format

Share Document