scholarly journals A prospective study of plasma vitamin D metabolites, vitamin D receptor gene polymorphisms, and risk of hypertension in men

2012 ◽  
Vol 52 (7) ◽  
pp. 1771-1779 ◽  
Author(s):  
Lu Wang ◽  
Jing Ma ◽  
JoAnn E. Manson ◽  
Julie E. Buring ◽  
J. Michael Gaziano ◽  
...  
2009 ◽  
Vol 1173 (1) ◽  
pp. 515-520 ◽  
Author(s):  
Joost Smolders ◽  
Jan Damoiseaux ◽  
Paul Menheere ◽  
Jan Willem Cohen Tervaert ◽  
Raymond Hupperts

Author(s):  
Surendar Aravindhan ◽  
Mohammed Fadhil Mohammed Almasoody ◽  
Nihad Abdallah Selman ◽  
Alekhina Natalia Andreevna ◽  
Sahithya Ravali ◽  
...  

2006 ◽  
Vol 175 (5) ◽  
pp. 1613-1623 ◽  
Author(s):  
Sonja I. Berndt ◽  
Jennifer L. Dodson ◽  
Wen-Yi Huang ◽  
Kristin K. Nicodemus

1970 ◽  
Vol 19 (4) ◽  
pp. 2812-2818
Author(s):  
Ayman S Al-Hazmi

Background: Type 2 diabetes mellitus (T2DM) is a global problem. Association of multiple genes in T2DM becomes a hot point recently. This study was aimed to evaluate association of vitamin D receptor gene polymorphisms with susceptibility to T2DM. Subjects and methods: One hundred T2DM Saudi male patients were included in this study and one hundred healthy Saudi men were used as control. For each individual, fasting blood glucose, cholesterol, HDL-C, LDL-C, HbA1c, insulin and 25-(OH) vitamin D were measured. In addition, Apal, BsmI and TaqI genotypes were performed for each subject. Data was analyzed by SPSS version 16, using Spearman's rho and ANOVA tests. Results: There was significant inverse correlation between 25-(OH) vitamin D level and T2DM (p<0.01). HbA1c was inversely correlated with 25-(OH) vitamin D level (P<0.05). Genotype study showed that tt of TaqI genotype was higher in T2DM group compared with control group (p<0.05). Moreover, tt genotype has higher HbA1c than both TT and Tt genotypes (p<0.05). Conclusion: An association was confirmed between TaqI genotypes and T2DM but there is no correlation between BsmI, ApaI and T2DM. In addition, HbA1c is positively correlated with tt genotype of TaqI.Keywords: Vitamin D receptor, diabetes type 2, polymorphism.


The Lancet ◽  
1995 ◽  
Vol 345 (8947) ◽  
pp. 423-424 ◽  
Author(s):  
S. Ferrari ◽  
R. Rizzoli ◽  
T. Chevalley ◽  
J.A. Eisman ◽  
J-P. Bonjour ◽  
...  

2016 ◽  
Vol 26 (1) ◽  
pp. 267-277 ◽  
Author(s):  
Hua Jiang ◽  
Zhilin Qin ◽  
Shaohui Zong ◽  
Maolin He ◽  
Xinli Zhan ◽  
...  

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