Higher fruit and vegetable variety associated with lower risk of cognitive impairment in Chinese community-dwelling older men: a 4-year cohort study

2022 ◽  
Author(s):  
Suey S. Y. Yeung ◽  
Timothy Kwok ◽  
Jean Woo
Keyword(s):  
Cohort Study ◽  
Cognitive Impairment ◽  
Lower Risk ◽  
Older Men ◽  
Community Dwelling ◽  
Chinese Community ◽  
Fruit And Vegetable

scholarly journals Relations of magnesium intake to cognitive impairment and dementia among participants in the Women’s Health Initiative Memory Study: a prospective cohort study

BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e030052 ◽  
Author(s):  
Kenneth Lo ◽  
Qing Liu ◽  
Tracy Madsen ◽  
Steve Rapp ◽  
Jiu-Chiuan Chen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cognitive Impairment ◽  
Women's Health ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Lower Risk ◽  
Women's Health Initiative ◽  
Women’S Health Initiative ◽  
Health Initiative ◽  
The Women’S Health Initiative

ObjectiveTo examine the associations of dietary and supplemental magnesium (Mg) as assessed by a semi-quantitative food frequency questionnaire with cognitive outcomes among ageing women.DesignThis work conducts a prospective cohort study of participants enrolled in the Women’s Health Initiative Memory Study (WHIMS), which was subsequently extended and named WHIMS-Epidemiology of Cognitive Health.SettingForty clinical centres in the USA.ParticipantsPostmenopausal women aged 65–79 years without dementia on enrolment.Main outcome measuresPhysician-adjudicated mild cognitive impairment (MCI) and/or probable dementia (PD).ResultsParticipants were excluded (n=1006) if they had extreme values of dietary energy intake, had missing or extreme body mass index values, with prevalent MCI/PD at baseline, received only one cognitive assessment or had been followed up for <1 year. During >20 years of follow-up, 765 (11.8%) out of 6473 participants developed MCI/PD. For MCI/PD and MCI, the risks tended to be lower among participants in quintiles Q2–Q5 of Mg consumption compared with those in the lowest quintile. Participants in Q3 had a significantly lower risk of MCI/PD (HR 0.69, 95% CI 0.53 to 0.91) and MCI (HR 0.63, 95% CI 0.45 to 0.87) after multivariate adjustments. No significant association was observed between total Mg intake and PD. The association between total Mg intake, MCI/PD and MCI was non-linear as suggested by the likelihood test.ConclusionsTotal Mg intake between the estimated average requirement and the recommended dietary allowances may associate with a lower risk of MCI/PD and MCI.Trial registration numberNCT00685009.

scholarly journals ACE inhibitors, statins and thiazides: no association with change in grip strength among community dwelling older men and women from the Hertfordshire Cohort Study

2014 ◽  
Vol 43 (5) ◽  
pp. 661-666 ◽  
Author(s):  
Miles D. Witham ◽  
Holly E. Syddall ◽  
Elaine Dennison ◽  
Cyrus Cooper ◽  
Marion E. T. McMurdo ◽  
...  
Keyword(s):  
Cohort Study ◽  
Grip Strength ◽  
Ace Inhibitors ◽  
Older Men ◽  
Community Dwelling ◽  
Men And Women ◽  
Hertfordshire Cohort Study ◽  
Older Men And Women

scholarly journals Daily step count and incident diabetes in community-dwelling 70-year-olds: a prospective cohort study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Marcel Ballin ◽  
Peter Nordström ◽  
Johan Niklasson ◽  
Antti Alamäki ◽  
Joan Condell ◽  
...  
Keyword(s):  
Older Adults ◽  
Cohort Study ◽  
Dose Response ◽  
Prospective Cohort ◽  
Lower Risk ◽  
Community Dwelling ◽  
Step Count ◽  
Incident Diabetes ◽  
Daily Step ◽  
Daily Step Count

Abstract Background Older adults with diabetes take fewer steps per day than those without diabetes. The purpose of the present study was to investigate the association of daily step count with incident diabetes in community-dwelling 70-year-olds. Methods This prospective cohort study included N = 3055 community-dwelling 70-year-olds (52% women) who participated in a health examination in Umeå, Sweden during 2012–2017, and who were free from diabetes at baseline. Daily step count was measured for 1 week using Actigraph GT3X+ accelerometers. Cases of diabetes were collected from the Swedish National Patient Register. The dose-response association was evaluated graphically using a flexible parametric model, and hazard ratios (HR) with 95% confidence intervals (CI) were calculated using Cox regressions. Results During a mean follow-up of 2.6 years, diabetes was diagnosed in 81 participants. There was an inverse nonlinear dose-response association between daily step count and incident diabetes, with a steep decline in risk of diabetes from a higher daily step count until around 6000 steps/day. From there, the risk decreased at a slower rate until it leveled off at around 8000 steps/day. A threshold of 4500 steps/day was found to best distinguish participants with the lowest risk of diabetes, where those taking ≥ 4500 steps/day, had 59% lower risk of diabetes, compared to those taking fewer steps (HR, 0.41, 95% CI, 0.25–0.66). Adjusting for visceral adipose tissue (VAT) attenuated the association (HR, 0.64, 95% CI, 0.38–1.06), which was marginally altered after further adjusting for sedentary time, education and other cardiometabolic risk factors and diseases (HR, 0.58, 95% CI, 0.32–1.05). Conclusions A higher daily step count is associated with lower risk of incident diabetes in community-dwelling 70-year-olds. The greatest benefits occur at the lower end of the activity range, and much earlier than 10,000 steps/day. With the limitation of being an observational study, these findings suggest that promoting even a modest increase in daily step count may help to reduce the risk of diabetes in older adults. Because VAT appears to partly mediate the association, lifestyle interventions targeting diabetes should apart from promoting physical activity also aim to prevent and reduce central obesity.

scholarly journals Prevalence and correlates of frailty among community-dwelling older men and women: findings from the Hertfordshire Cohort Study

2009 ◽  
Vol 39 (2) ◽  
pp. 197-203 ◽  
Author(s):  
H. Syddall ◽  
H. C Roberts ◽  
M. Evandrou ◽  
C. Cooper ◽  
H. Bergman ◽  
...  
Keyword(s):  
Cohort Study ◽  
Older Men ◽  
Community Dwelling ◽  
Men And Women ◽  
Hertfordshire Cohort Study ◽  
Older Men And Women

scholarly journals Certain dietary patterns are associated with GLIM criteria among Chinese community-dwelling older adults: a cross-sectional analysis

2021 ◽  
Vol 10 ◽  
Author(s):  
Suey S. Y. Yeung ◽  
Ruth S. M. Chan ◽  
Jenny S. W. Lee ◽  
Jean Woo
Keyword(s):  
Older Adults ◽  
Dietary Patterns ◽  
Lower Risk ◽  
Binary Logistic Regression ◽  
Community Dwelling ◽  
Dietary Quality ◽  
Milk Product ◽  
Chinese Community ◽  
Cross Sectional ◽  
Community Dwelling Older Adults

Abstract Disease-related malnutrition is prevalent among older adults; therefore, identifying the modifiable risk factors in the diet is essential for the prevention and management of disease-related malnutrition. The present study examined the cross-sectional association between dietary patterns and malnutrition in Chinese community-dwelling older adults aged ≥65 years in Hong Kong. Dietary patterns, including Diet Quality Index International (DQI-I), Dietary Approaches to Stop Hypertension (DASH), the Mediterranean Diet Score, ‘vegetable–fruit’ pattern, ‘snack–drink–milk product’ pattern and ‘meat–fish’ pattern, were estimated and generated from a validated food frequency questionnaire. Malnutrition was classified according to the modified Global Leadership Initiative on Malnutrition (GLIM) criteria based on two phenotypic components (low body mass index and reduced muscle mass) and one aetiologic component (inflammation/disease burden). The association between the tertile or level of adherence of each dietary pattern and modified GLIM criteria was analysed using adjusted binary logistic regression models. Data of 3694 participants were available (49 % men). Malnutrition was present in 397 participants (10⋅7 %). In men, a higher DQI-I score, a higher ‘vegetable–fruit’ pattern score and a lower ‘meat–fish’ pattern score were associated with a lower risk of malnutrition. In women, higher adherence to the DASH diet was associated with a lower risk of malnutrition. After the Bonferroni correction, the association remained statistically significant only in men for the DQI-I score. To conclude, a higher DQI-I score was associated with a lower risk of malnutrition in Chinese older men. Nutritional strategies for the prevention and management of malnutrition could potentially be targeted on dietary quality.

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