Evaluation of biomechanical properties: are porcine flexor tendons and bovine extensor tendons eligible surrogates for human tendons in in vitro studies?

2016 ◽  
Vol 136 (10) ◽  
pp. 1465-1471 ◽  
Author(s):  
C. Domnick ◽  
B. Wieskötter ◽  
M. J. Raschke ◽  
M. Schulze ◽  
D. Kronenberg ◽  
...  
Keyword(s):  
Biomechanical Properties ◽  
In Vitro Studies ◽  
Extensor Tendons ◽  
Flexor Tendons

Biomechanical evaluation of the Pulvertaft versus the ‘wrap around’ tendon suture technique

2011 ◽  
Vol 36 (6) ◽  
pp. 461-466 ◽  
Author(s):  
S. P. Fuchs ◽  
E. T. Walbeehm ◽  
S. E. R. Hovius
Keyword(s):  
Tendon Repair ◽  
Surgical Techniques ◽  
Tensile Loading ◽  
Biomechanical Properties ◽  
Suture Technique ◽  
Extensor Tendons ◽  
Repair Method ◽  
Tendon Suture ◽  
Biomechanical Evaluation

The purpose of this study was to compare the biomechanical properties of a novel wrap around tendon repair method with those of the standard Pulvertaft technique used for tendon reconstructions. Seventy-two porcine extensor tendons were used to create 36 reconstructions in six sets of six repairs, each using one of the two surgical techniques with differing lengths of the reconstructions. All the reconstructions were tested in vitro by cyclic tensile loading, resulting in the time-zero strength. When only the size of the repair and the strength were compared, and length of the reconstruction was not taken in consideration, the ‘wrap around’ reconstructions were of similar strength but less bulky than the Pulvertaft repairs. In conclusion, the ‘wrap around’ technique gives a thinner reconstruction which is as strong as, or stronger than the Pulvertaft technique, depending on the amount of weaves.

Relationship between body mass and biomechanical properties of limb tendons in adult mammals

1994 ◽  
Vol 266 (3) ◽  
pp. R1016-R1021 ◽  
Author(s):  
C. M. Pollock ◽  
R. E. Shadwick
Keyword(s):  
Elastic Modulus ◽  
Body Mass ◽  
Strain Energy ◽  
Biomechanical Properties ◽  
Allometric Equation ◽  
Allometric Relationship ◽  
Total Strain Energy ◽  
Extensor Tendons ◽  
The Relationship

We investigated the allometric relationship between the mechanical properties of various limb tendons and body mass. The elastic modulus (i.e., stiffness) and hysteresis (i.e., energy dissipation) of digital flexor, ankle extensor, and digital extensor tendons from 18 species of adult quadrupedal mammals ranging in body mass from 0.5 to 545 kg were determined by cyclic tensile testing in vitro. The results show that these elastic properties do not vary significantly among tendons from animals of different body mass, nor do they differ between the digital flexor and ankle extensor tendons (those situated to act as springs during locomotion) and the digital extensor tendons (those not likely to function as springs during locomotion). Consequently, the inherent capability of different limb tendons to store elastic energy, based on their material properties, is the same for large and small animals. The relationship between tendon elastic modulus (E; in GPa) and body mass (Mb; in kg) is described by the allometric equation E = 1.22Mb0.00. The hysteresis (H), as a percentage of total strain energy, is related to body mass as H = 8.89Mb-0.03.

scholarly journals Biomechanical Behavior of Zirconia Post and Core In vitro: a Systematic Review

2020 ◽  
Vol 8 (3) ◽  
pp. 294-303
Author(s):  
Oskaras Godvaišas ◽  
Gediminas Žekonis ◽  
Laura Merkevičiūtė
Keyword(s):  
Systematic Review ◽  
Clinical Investigation ◽  
Case Reports ◽  
Biomechanical Properties ◽  
In Vitro Studies ◽  
Cochrane Library ◽  
Biomechanical Behavior ◽  
Anterior Teeth ◽  
Post And Core

Restoration of endodontically treated teeth is a common clinical practice which is being improved constantly. One piece zirconia post and cores are being introduced to dental treatments routine and offers aesthetic approach in restoring severely damaged teeth. However the biomechanical properties of such restorations remain unclear. The purpose of this systematic review was to describe biomechanical properties of zirconia post and cores and put them in a perspective with more conventional restorations. An electronic search was conducted in PubMed, Cochrane Library and Clinical Key databases for in vitro studies dating up to October 2019. Clinical studies and case reports were excluded. Results: a total of 8 articles were included in a systematic review, consisting of 4 in vitro studies and 4 finite element analysis (FEA). Several evaluation parameters were set: zirconia post and core fractural resistance comparison with metal and prefabricated post systems, stress distribution in teeth restored with zirconia post and cores. Conclusions: zirconia post and core could be a promising restoration for anterior teeth where aesthetic demand is high. It showed similar in vitro biomechanical behavior and fractural resistance to gold alloy restorations, although such findings only show a tendency and further clinical investigation is needed. Keywords: zirconia post and core, prosthetic dentistry, biomechanical behavior.

In vitro - studies with antler bone cells: Structure forming capacity, osteocalcin production and influence of sex steroids

2006 ◽  
Vol 15 (04) ◽  
pp. 245-257 ◽  
Author(s):  
H. J. Rolf ◽  
K. G. Wiese ◽  
H. Siggelkow ◽  
H. Schliephake ◽  
G. A. Bubernik
Keyword(s):  
Sex Steroids ◽  
Bone Cells ◽  
In Vitro Studies ◽  
Osteocalcin Production

In Vitro Studies on the Mechanism of the Antifibrino-lytic Action of E-Aminocaproic Acid (EACA)

1968 ◽  
Vol 19 (03/04) ◽  
pp. 584-592 ◽  
Author(s):  
Hanna Lukasiewicz ◽  
S Niewiarowski
Keyword(s):  
Aminocaproic Acid ◽  
Test Tube ◽  
In Vitro Studies ◽  
Lytic Action ◽  
Human Plasminogen ◽  
Experimental Findings ◽  
Fibrin Clots

Summary and Conclusion1. It has been found that EACA does not inhibit activation of human plasminogen into plasmin by SK and UK in a concentration of 5 × 10–2 M. The activation of bovine plasminogen by SK and UK is inhibited by this concentration of EACA but not by a lower one.2. EACA in concentrations of 1,5 × 10–1 – 10–4 M does not inhibit casein proteolysis by plasmin. The proteolysis of fibrinogen and fibrin measured by the release of TCA soluble tyrosine is inhibited by EACA in concentrations of 1,5 × 10–1 – 10–2 M.3. The lysis of non-stabilized clots by plasmin measured in a test tube was inhibited by an EACA concentration of 5 × 10–3 – 5 × 10–4 M. The lysis of stabilized clots by plasmin was inhibited by an EACA concentration of 10–5 M.4. On the basis of experimental findings and data given in literature the authors postulate that the mechanism of the antifibrinolytic effects of EACA consists mainly in a modification of plasmin action on fibrin. These effects are dependent on the structure of the fibrin clots.

The Venom of the Boomslang (Dispholidus Typus): In Vivo and in Vitro Studies

1969 ◽  
Vol 21 (02) ◽  
pp. 234-244 ◽  
Author(s):  
N Mackay ◽  
J.C Ferguson ◽  
Antonia Bagshawe ◽  
A.T.T Forrester ◽  
G.P Mcnicol
Keyword(s):  
In Vitro Studies

SummaryAn account is given of the effects of boomslang venom in man. Evidence was found of a fibrinolytic state apparently secondary to the coagulant action of the venom. These features rapidly responded to the administration of specific antivenom. In vitro studies, using a homogenate of boomslang parotids, confirmed the coagulant properties of the venom and showed them to be of much greater potency than the proteolytic actions.

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