Nomogram with potential clinical use to predict lymph node metastasis in endometrial cancer patients diagnosed incidentally by postoperative pathological assessment

2017 ◽  
Vol 296 (4) ◽  
pp. 803-809 ◽  
Author(s):  
Salih Taşkın ◽  
Yavuz Emre Şükür ◽  
Bulut Varlı ◽  
Kazibe Koyuncu ◽  
Mehmet Murat Seval ◽  
...  
2018 ◽  
Vol 119 (3) ◽  
pp. 361-369 ◽  
Author(s):  
Jan Kosťun ◽  
Martin Pešta ◽  
Jiří Sláma ◽  
Robert Slunéčko ◽  
Pavel Vlasák ◽  
...  

Author(s):  
Hui-Hua Chen ◽  
Wan-Hua Ting ◽  
Hsu-Dong Sun ◽  
Ming-Chow Wei ◽  
Ho-Hsiung Lin ◽  
...  

Background: to elucidate the predictors of progression-free survival (PFS) and overall survival (OS) in high-risk endometrial cancer patients. Methods: the medical records of all consecutivewomen with high-risk endometrial cancer were reviewed. Results: among 92 high-risk endometrial cancer patients, 30 women experienced recurrence, and 21 women died. The 5-year PFS and OS probabilities were 65.3% and 75.9%, respectively. Multivariable Cox regression revealed that body mass index (hazard ratio (HR) = 1.11), paraaortic lymph node metastasis (HR = 11.11), lymphovascular space invasion (HR = 5.61), and sandwich chemoradiotherapy (HR = 0.15) were independently predictors of PFS. Body mass index (HR = 1.31), paraaortic lymph node metastasis (HR = 32.74), non-endometrioid cell type (HR = 11.31), and sandwich chemoradiotherapy (HR = 0.07) were independently predictors of OS. Among 51 women who underwent sandwich (n = 35) or concurrent (n = 16) chemoradiotherapy, the use of sandwich chemoradiotherapy were associated with better PFS (adjusted HR = 0.26, 95% CI = 0.08–0.87, p = 0.03) and OS (adjusted HR = 0.11, 95% CI = 0.02–0.71, p = 0.02) compared with concurrent chemoradiotherapy. Conclusion: compared with concurrent chemoradiotherapy, sandwich chemoradiotherapy was associated with better PFS and OS in high-risk endometrial cancer patients. In addition, high body mass index, paraaortic lymph node metastasis, and non-endometrioid cell type were also predictors of poor OS in high-risk endometrial cancer patients.


2017 ◽  
Vol 116 (2) ◽  
pp. 220-226 ◽  
Author(s):  
Glauco Baiocchi ◽  
Carlos Chaves Faloppa ◽  
Henrique Mantoan ◽  
Willian Ricardo Camarço ◽  
Levon Badiglian-Filho ◽  
...  

Clinics ◽  
2017 ◽  
Vol 72 (1) ◽  
pp. 30-35 ◽  
Author(s):  
C Anton ◽  
AS Silva ◽  
EC Baracat ◽  
NU Dogan ◽  
C Köhler ◽  
...  

Oncology ◽  
2019 ◽  
Vol 96 (5) ◽  
pp. 259-267 ◽  
Author(s):  
Tadashi Aoyama ◽  
Masashi Takano ◽  
Morikazu Miyamoto ◽  
Tomoyuki Yoshikawa ◽  
Kento Kato ◽  
...  

2021 ◽  
pp. 096032712110085
Author(s):  
Z Li ◽  
W Zhang ◽  
Z Luo ◽  
J Huang ◽  
L Li

To analyze the clinical characteristics and prognosis of endometrial cancer patients with lymph node metastasis to provide a reference for lymphadenectomy in endometrial cancer. The data used in this study were extracted from a tertiary hospital in Guangxi, China based on the hospital information system. 1219 patients with endometrial malignancy who were treated in our hospital. The lymph node metastasis rate was 9.8%. The metastasis rate of the abdominal aorta + pelvic lymph nodes (56.7%) was significantly higher than that of the pelvic (24.2%) or para-aortic (19.2%) lymph nodes alone. The proportion of postmenopausal patients with lymph node metastasis was higher than that of premenopausal patients. The proportion of patients with lymph node metastasis with vaginal and uterus involvement, HPV detection, Thinprep Cytologic Testresults, CRP level <10 ug/mL, G3 tumor grade, postoperative pathology indicating cervical invasion, lymphovascular invasion, and muscular infiltration depth > 1/2 was higher than that of patients without lymph node metastasis. The proportion of endometrial cancer patients with lymph node metastasis with CA125 ≥ 35 U/ml was higher than that of those with CA125 < 35 U/ml. The lymph node-positive rate is related to tissue differentiation, lymphangitic infiltration, cervical invasion, muscle infiltration depth > 1/2, and CA125 level. The metastasis rate of pelvic and para-aortic lymph nodes is higher than that of pelvic lymph nodes or para-aortic lymph nodes alone. There was no statistically significant difference in the overall survival rate among the three groups.


1998 ◽  
Vol 71 (3) ◽  
pp. 424-427 ◽  
Author(s):  
Wen-Fang Cheng ◽  
Chi-An Chen ◽  
Chien-Nan Lee ◽  
Tzer-Ming Chen ◽  
Kuang-Ta Huang ◽  
...  

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