Effects of 3-month high-intensity interval training vs. moderate endurance training and 4-month follow-up on fat metabolism, cardiorespiratory function and mitochondrial respiration in obese adults

2020 ◽  
Vol 120 (8) ◽  
pp. 1787-1803
Author(s):  
Filippo Vaccari ◽  
Angelina Passaro ◽  
Andrea D’Amuri ◽  
Juana Maria Sanz ◽  
Francesca Di Vece ◽  
...  
Keyword(s):  
Endurance Training ◽  
Mitochondrial Respiration ◽  
High Intensity ◽  
Fat Metabolism ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Obese Adults ◽  
Cardiorespiratory Function ◽  
High Intensity Interval

scholarly journals Effects of high-intensity interval training on microvascular glycocalyx and associated microRNAs

2019 ◽  
Vol 316 (6) ◽  
pp. H1538-H1551 ◽  
Author(s):  
Boris Schmitz ◽  
Hannah Niehues ◽  
Malte Lenders ◽  
Lothar Thorwesten ◽  
Andreas Klose ◽  
...  
Keyword(s):  
High Intensity ◽  
Interval Training ◽  
Dark Field ◽  
Endothelial Glycocalyx ◽  
High Intensity Interval Training ◽  
Sidestream Dark Field ◽  
Sidestream Dark Field Imaging ◽  
High Intensity Interval ◽  
Glycocalyx Thickness

High-intensity interval training (HIIT) has been proposed to exert vasculoprotective effects. This study aimed to evaluate whether HIIT affects the microvasculature, including the endothelial glycocalyx barrier, and to identify associated microRNAs (miRNAs). Fifty healthy participants (23.1 ± 3.0 yr) performed a 4-wk 4 × 30-s all-out running HIIT. Sidestream dark-field imaging was performed at baseline and follow-up to detect changes of the sublingual microvasculature including the endothelial glycocalyx. Exercise parameters were determined by continuous running field test and documentation of high-intensity runs. miRNAs potentially associated with glycocalyx thickness were selected by structured literature search and blood samples for miRNA, and lactate measurements were drawn at baseline and follow-up HIIT. At baseline, a correlation between maximal exercise performance capacity and glycocalyx thickness (determined by perfused boundary region) was detected ( P = 0.045, r = 0.303). Increased exercise performance at follow-up also correlated with glycocalyx thickness ( P = 0.031, r = 0.416), and increased high-intensity sprinting speed was associated with an increased number of perfused vessels ( P = 0.0129, r = 0.449). Literature search identified miR-143, -96-5p, and -24, which were upregulated by HIIT already at baseline and showed an association with peak blood lactate levels after sprints (all P < 0.05). Moreover, increased baseline miR-143 levels predicted increased glycocalyx thickness at follow-up (AUCmiR-143 = 0.92, 95% confidence interval, 0.81–1.0, P = 0.0008). Elevated resting miR-126 levels after the intervention were associated with cell-free versican mRNA levels. We conclude that HIIT induces changes in the endothelial glycocalyx of the microvasculature. Associated miRNAs such as miR-143 may represent a tool for monitoring early vasculoprotective adaptations to physical activity. NEW & NOTEWORTHY High-intensity interval training is known to improve health-related fitness in general and in lifestyle-induced chronic diseases. To visualize microvasculature structure and to detect exercise-induced changes, sublingual sidestream dark-field imaging microscopy was used, and circulating miRNAs were measured. This study shows that exercise-induced changes correlate with associated circulating miRNA, which might be useful for monitoring vasculoprotective effects. Furthermore, sidestream dark-field imaging may represent a sensitive tool for the early detection of exercise-induced systemic vascular changes.

scholarly journals High-intensity interval training reduces monocyte activation in obese adults

2019 ◽  
Vol 80 ◽  
pp. 818-824 ◽  
Author(s):  
Mariana Aguiar de Matos ◽  
Bruna Caroline Chaves Garcia ◽  
Dênia Vargas Vieira ◽  
Marcos Felipe Andrade de Oliveira ◽  
Karine Beatriz Costa ◽  
...  
Keyword(s):  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Monocyte Activation ◽  
Obese Adults ◽  
High Intensity Interval

scholarly journals Cognitive effectiveness of high-intensity interval training for individuals with methamphetamine dependence: a study protocol for randomised controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shen Menglu ◽  
Yang Suyong ◽  
Wang Xiaoyan ◽  
Wolfgang I. Schöllhorn ◽  
Zhu Dong
Keyword(s):  
Cognitive Functions ◽  
High Intensity ◽  
Interval Training ◽  
Moderate Intensity ◽  
Good Effect ◽  
High Intensity Interval Training ◽  
Link Type ◽  
Short Period ◽  
High Intensity Interval

Abstract Introduction Cognitive deficit is a common syndrome of methamphetamine (MA) dependence. It is related to decision-making, control ability, and social functioning. High-intensity interval training (HIIT) is a training technique that requires people to work out at full intensity during a short period. Many studies have already shown the potential effects of HIIT on cognitive functions. The purpose of this trial is to evaluate the cognitive effects of HIIT on individuals with MA dependence. Methods and analysis A total of 240 individuals with MA dependence will be randomly assigned to the HIIT group, moderate-intensity continuous training (MICT) group and control (CON) group. HIIT will consist of a 24-min HIIT exercise on a treadmill. MICT will consist of a 1-h body–mind exercise. CON will be their traditional intervention. The experimental period will be 12 months with 3 interventions weekly for the first 6 months and follow-up for the next 6 months. All subjects will be given cognitive tests at baseline, after intervention and at follow-up. Cognitive performances will be compared by a mixed-model analysis for repeated measures. Discussion HIIT training may reduce illicit drug cravings amongst individuals with MA dependence; hence, HIIT may have a good effect on the cognitive functions, such as memory and executive function, of individuals with MA dependence. Trial registration Chinese Clinical Trial Registry ChiCTR2000032492. Registered on April 30, 2020 (http://www.chictr.org.cn/edit.aspx?pid=52127&htm=4)

scholarly journals The effects of high intensity interval training on muscle size and quality in overweight and obese adults

2018 ◽  
Vol 21 (2) ◽  
pp. 207-212 ◽  
Author(s):  
Malia N.M. Blue ◽  
Abbie E. Smith-Ryan ◽  
Eric T. Trexler ◽  
Katie R. Hirsch
Keyword(s):  
High Intensity ◽  
Interval Training ◽  
Muscle Size ◽  
High Intensity Interval Training ◽  
Obese Adults ◽  
High Intensity Interval
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