Skeletal muscle buffering capacity and endurance performance after high-intensity interval training by well-trained cyclists

1996 ◽  
Vol 75 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Ad�le R. Weston ◽  
K. H. Myburgh ◽  
F. H. Lindsay ◽  
Steven C. Dennis ◽  
Timothy D. Noakes ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
High Intensity ◽  
Interval Training ◽  
Endurance Performance ◽  
Buffering Capacity ◽  
High Intensity Interval Training ◽  
Muscle Buffering Capacity ◽  
High Intensity Interval ◽  
Muscle Buffering

scholarly journals EFFECTS OF HIGH-INTENSITY INTERVAL TRAINING ON SKELETAL MUSCLE MITOCHONDRIAL QUALITY CONTROL IN DIET-INDUCED OBESE MICE

2021 ◽  
Vol 53 (8S) ◽  
pp. 117-117
Author(s):  
Kai Zou ◽  
James B. Tincknell ◽  
Benjamin A. Kugler ◽  
Haley Spicuzza ◽  
Paul Nguyen ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Quality Control ◽  
High Intensity ◽  
Interval Training ◽  
Obese Mice ◽  
High Intensity Interval Training ◽  
Mitochondrial Quality Control ◽  
High Intensity Interval

scholarly journals High-Intensity Interval Training Improves Markers of Oxidative Metabolism in Skeletal Muscle of Individuals With Obesity and Insulin Resistance

2018 ◽  
Vol 9 ◽  
Author(s):  
Mariana Aguiar de Matos ◽  
Dênia Vargas Vieira ◽  
Kaio Cesar Pinhal ◽  
Jennifer Freitas Lopes ◽  
Marco Fabrício Dias-Peixoto ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Skeletal Muscle ◽  
Oxidative Metabolism ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval

The effect of high intensity interval training on some atrophic and anti-atrophic gene expression in rat skeletal muscle with diabetes

2020 ◽  
Vol 35 (3) ◽  
pp. e75-e81
Author(s):  
M. Kordi ◽  
S. Khoramshahi ◽  
S. Eshghi ◽  
A. Gaeeni ◽  
A. Moosakhani
Keyword(s):  
Gene Expression ◽  
Skeletal Muscle ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Rat Skeletal Muscle ◽  
High Intensity Interval

Effects of one‐legged high‐intensity interval training on insulin‐mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes

2019 ◽  
Vol 226 (2) ◽  
pp. e13245 ◽  
Author(s):  
Flemming Dela ◽  
Arthur Ingersen ◽  
Nynne B. Andersen ◽  
Maria B. Nielsen ◽  
Helga H. H. Petersen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Skeletal Muscle ◽  
Glucose Homeostasis ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval

scholarly journals High intensity interval training and molecular adaptive response of skeletal muscle

2019 ◽  
Vol 1 (1) ◽  
pp. 24-32 ◽  
Author(s):  
Ferenc Torma ◽  
Zoltan Gombos ◽  
Matyas Jokai ◽  
Masaki Takeda ◽  
Tatsuya Mimura ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
High Intensity ◽  
Adaptive Response ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval

High-intensity interval training increases SIRT1 activity in human skeletal muscle

2010 ◽  
Vol 35 (3) ◽  
pp. 350-357 ◽  
Author(s):  
Brendon J. Gurd ◽  
Christopher G.R. Perry ◽  
George J.F. Heigenhauser ◽  
Lawrence L. Spriet ◽  
Arend Bonen
Keyword(s):  
Skeletal Muscle ◽  
High Intensity ◽  
Human Skeletal Muscle ◽  
Citrate Synthase ◽  
Interval Training ◽  
Peak Oxygen Consumption ◽  
Peroxisome Proliferator ◽  
Mitochondrial Enzymes ◽  
High Intensity Interval Training ◽  
High Intensity Interval

The effects of training on silent mating-type information regulator 2 homolog 1 (SIRT1) activity and protein in relationship to peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitochondrial content were determined in human skeletal muscle. Six weeks of high-intensity interval training (∼1 h of 10 × 4 min intervals at 90% peak oxygen consumption separated by 2 min rest, 3 days per week) increased maximal activities of mitochondrial enzymes in skeletal muscle by 28% to 36% (citrate synthase, β-hydroxyacyl-coenzyme A dehydrogenase, and cytochrome c oxidase subunit IV) and PGC-1α protein (16%) when measured 4 days after training. Interestingly, total muscle SIRT1 activity (31%) and activity per SIRT1 protein (58%) increased despite decreased SIRT1 protein (20%). The present data demonstrate that exercise-induced mitochondrial biogenesis is accompanied by elevated SIRT1 activity in human skeletal muscle.

An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscle

2011 ◽  
Vol 300 (6) ◽  
pp. R1303-R1310 ◽  
Author(s):  
Jonathan P. Little ◽  
Adeel Safdar ◽  
David Bishop ◽  
Mark A. Tarnopolsky ◽  
Martin J. Gibala
Keyword(s):  
Skeletal Muscle ◽  
Mitochondrial Biogenesis ◽  
High Intensity ◽  
Human Skeletal Muscle ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Acute Bout ◽  
Nuclear Abundance ◽  
Low Volume ◽  
High Intensity Interval

Low-volume, high-intensity interval training (HIT) increases skeletal muscle mitochondrial capacity, yet little is known regarding potential mechanisms promoting this adaptive response. Our purpose was to examine molecular processes involved in mitochondrial biogenesis in human skeletal muscle in response to an acute bout of HIT. Eight healthy men performed 4 × 30-s bursts of all-out maximal intensity cycling interspersed with 4 min of rest. Muscle biopsy samples (vastus lateralis) were obtained immediately before and after exercise, and after 3 and 24 h of recovery. At rest, the majority of peroxisome proliferator-activated receptor γ coactivator (PGC)-1α, a master regulator of mitochondrial biogenesis, was detected in cytosolic fractions. Exercise activated p38 MAPK and AMPK in the cytosol. Nuclear PGC-1α protein increased 3 h into recovery from exercise, a time point that coincided with increased mRNA expression of mitochondrial genes. This was followed by an increase in mitochondrial protein content and enzyme activity after 24 h of recovery. These findings support the hypothesis that an acute bout of low-volume HIT activates mitochondrial biogenesis through a mechanism involving increased nuclear abundance of PGC-1α.

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