scholarly journals The embryonic expression pattern of a second, hitherto unrecognized, paralog of the pair-rule gene sloppy-paired in the beetle Tribolium castaneum

2020 ◽  
Vol 230 (3) ◽  
pp. 247-256
Author(s):  
Ralf Janssen
Keyword(s):  
Expression Pattern ◽  
Tribolium Castaneum ◽  
Pair Rule Gene ◽  
Pair Rule

scholarly journals Tc-knirps plays different roles in the specification of antennal and mandibular parasegment boundaries and is regulated by a pair-rule gene in the beetle Tribolium castaneum

2013 ◽  
Vol 13 (1) ◽  
pp. 25 ◽  
Author(s):  
Andrew D Peel ◽  
Julia Schanda ◽  
Daniela Grossmann ◽  
Frank Ruge ◽  
Georg Oberhofer ◽  
...  
Keyword(s):  
Tribolium Castaneum ◽  
Pair Rule Gene ◽  
Pair Rule

Expression domains of a zebrafish homologue of the Drosophila pair-rule gene hairy correspond to primordia of alternating somites

Development ◽  
1996 ◽  
Vol 122 (7) ◽  
pp. 2071-2078 ◽  
Author(s):  
M. Muller ◽  
E. Weizsacker ◽  
J.A. Campos-Ortega
Keyword(s):  
Expression Pattern ◽  
Bhlh Protein ◽  
Presomitic Mesoderm ◽  
Tail Bud ◽  
Expression Domain ◽  
Somite Formation ◽  
Pair Rule Gene ◽  
Pair Rule ◽  
Time Point

her1 is a zebrafish cDNA encoding a bHLH protein with all features characteristic of members of the Drosophila HAIRY-E(SPL) family. During late gastrulation stages, her1 is expressed in the epibolic margin and in two distinct transverse bands of hypoblastic cells behind the epibolic front. After completion of epiboly, this pattern persists essentially unchanged through postgastrulation stages; the marginal domain is incorporated in the tail bud and, depending on the time point, either two or three paired bands of expressing cells are present within the paraxial presomitic mesoderm separated by regions devoid of transcripts. Labelling of cells within the her1 expression domains with fluorescein-dextran shows that the cells in the epibolic margin and the tail bud are not allocated to particular somites. However, allocation of cells to somites occurs between the marginal expression domain and the first expression band, anterior to it. Moreover, the her1 bands, and the intervening non-expressing zones, each represents the primordium of a somite. This expression pattern is highly reminiscent of that of Drosophila pair-rule genes. A possible participation of her1 in functions related to somite formation is discussed.

scholarly journals Analysis of maxillopedia Expression Pattern and Larval Cuticular Phenotype in Wild-Type and Mutant Tribolium

Genetics ◽  
2000 ◽  
Vol 155 (2) ◽  
pp. 721-731 ◽  
Author(s):  
Teresa D Shippy ◽  
Jianhua Guo ◽  
Susan J Brown ◽  
Richard W Beeman ◽  
Robin E Denell
Keyword(s):  
Rna Interference ◽  
Expression Pattern ◽  
Tribolium Castaneum ◽  
Expression Patterns ◽  
Ectopic Expression ◽  
Homeotic Gene ◽  
Wild Type ◽  
Double Stranded Rna ◽  
Similar Expression ◽  
Mutant Phenotypes

Abstract The Tribolium castaneum homeotic gene maxillopedia (mxp) is the ortholog of Drosophila proboscipedia (pb). Here we describe and classify available mxp alleles. Larvae lacking all mxp function die soon after hatching, exhibiting strong transformations of maxillary and labial palps to legs. Hypomorphic mxp alleles produce less severe transformations to leg. RNA interference with maxillopedia double-stranded RNA results in phenocopies of mxp mutant phenotypes ranging from partial to complete transformations. A number of gain-of-function (GOF) mxp alleles have been isolated based on transformations of adult antennae and/or legs toward palps. Finally, we have characterized the mxp expression pattern in wild-type and mutant embryos. In normal embryos, mxp is expressed in the maxillary and labial segments, whereas ectopic expression is observed in some GOF variants. Although mxp and Pb display very similar expression patterns, pb null embryos develop normally. The mxp mutant larval phenotype in Tribolium is consistent with the hypothesis that an ancestral pb-like gene had an embryonic function that was lost in the lineage leading to Drosophila.

odd Oz: A novel Drosophila pair rule gene

Cell ◽  
1994 ◽  
Vol 77 (4) ◽  
pp. 587-598 ◽  
Author(s):  
Anna Levine ◽  
Ayelet Bashan-Ahrend ◽  
Ofra Budai-Hadrian ◽  
Devorah Gartenberg ◽  
Sophia Menasherow ◽  
...  
Keyword(s):  
Pair Rule Gene ◽  
Pair Rule

Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain

1999 ◽  
Vol 112 (12) ◽  
pp. 2019-2032 ◽  
Author(s):  
A.D. Minet ◽  
B.P. Rubin ◽  
R.P. Tucker ◽  
S. Baumgartner ◽  
R. Chiquet-Ehrismann
Keyword(s):  
Sequence Motifs ◽  
Heparin Binding ◽  
Terminal Part ◽  
Phylogenetic Conservation ◽  
Neuronal Protein ◽  
Repeat Proteins ◽  
Heparin Binding Domain ◽  
Pair Rule Gene ◽  
Pair Rule

The Drosophila gene ten-m is the first pair-rule gene not encoding a transcription factor, but an extracellular protein. We have characterized a highly conserved chicken homologue that we call teneurin-1. The C-terminal part harbors 26 repetitive sequence motifs termed YD-repeats. The YD-repeats are most similar to the core of the rhs elements of Escherichia coli. Related repeats in toxin A of Clostridium difficile are known to bind specific carbohydrates. We show that recombinantly expressed proteins containing the YD-repeats of teneurin-1 bind to heparin. Furthermore, heparin lyase treatment of extracts of cells expressing recombinant YD-repeat protein releases this protein from high molecular mass aggregates. In situ hybridization and immunostaining reveals teneurin-1 expression in neurons of the developing visual system of chicken and Drosophila. This phylogenetic conservation of neuronal expression from flies to birds implies fundamental roles for teneurin-1 in neurogenesis. This is supported by the neurite outgrowth occurring on substrates made of recombinant YD-repeat proteins, which can be inhibited by heparin. Database searches resulted in the identification of ESTs encoding at least three further members of the teneurin family of proteins. Furthermore, the human teneurin-1 gene could be identified on chromosome Xq24/25, a region implied in an X-linked mental retardation syndrome.

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