Influence of vitamin D signaling on hormone receptor status and HER2 expression in breast cancer

Breast cancer is the major health problem for the women throughout the world.Management of breast cancer has evolved to include both surgery for local disease and medical therapy for systemic disease. Multiple treatment options are available depending on various factors such as histological grade, hormone receptor status etc. The aim of this study is to correlate the hormone receptor status with prognostic factors such as lymph node involvement, tumour grading and age among patients diagnosed with breast cancer in our institution. The results of this study serve to prognosticate the severity of disease among various strata of patients.

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Is the biology of breast cancer changing? A study of hormone receptor status 1984–86 and 1996–1997

European Journal of Surgical Oncology ◽

10.1016/j.ejso.2008.06.079 ◽

2008 ◽

Vol 34 (10) ◽

pp. 1172

Author(s):

Sylvia Brown ◽

E. Mallon ◽

J. Edwards ◽

F. Campbell ◽

L. McGlynn ◽

...

Keyword(s):

Breast Cancer ◽

Hormone Receptor ◽

Hormone Receptor Status ◽

Receptor Status

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Hormone Receptor Status in Breast Cancer and its Relation to Age and Other Prognostic Factors at Tertiary Care Hospital at Central India

New Indian Journal of Surgery ◽

10.21088/nijs.0976.4747.11220.14 ◽

2020 ◽

Vol 11 (2) ◽

pp. 164-169

Author(s):

Raju W Gore

Keyword(s):

Breast Cancer ◽

Prognostic Factors ◽

Hormone Receptor ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Central India ◽

Hormone Receptor Status ◽

Care Hospital ◽

Receptor Status

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Effect of intraoperative radiotherapy on wound healing in breast cancer patient post breast conserving surgery, KSUMC, Riyadh, Saudi Arabia: Case series and review of literature.

International Journal Of Medical Science And Clinical Invention ◽

10.18535/ijmsci/v6i6.04 ◽

2019 ◽

Vol 6 (06) ◽

pp. 4505-4510

Author(s):

Dr. Maha Alamodi Alghamdi ◽

Abdulaziz Saleh Altwjri ◽

Abdullah Alsuhaibani ◽

Abdulaziz Alsaif

Keyword(s):

Breast Cancer ◽

Hormone Receptor ◽

External Beam Radiotherapy ◽

Intraoperative Radiotherapy ◽

Breast Conserving Surgery ◽

Hormone Receptor Status ◽

Wound Complications ◽

External Beam ◽

X Rays ◽

Receptor Status

Intraoperative radiotherapy during breast-conserving surgery is being studied as an alternative to 6 weeks of external beam radiotherapy (EBRT) for low-risk women; it can be delivered using electrons (intraoperative electron radiotherapy, IOERT) or 50-kV X-rays. Intraoperative radiation therapy (IORT) may pose a risk for wound complications. Between March 2018 and June 2018, 5 breast cancer patients, all eligible for breast conserving surgery (BCS), were treated at the King Saud Medical city with IORT using the IOERT. Complete data sets for age, stage (T, N, and M), and histology and hormone receptor status were available in 5 cases. Parameters to identify eligible patients are as follows: ESTRO: >50 years, invasive ductal carcinoma/other favourable histology (IDC), T1-2 (≤3 cm), N0, any hormone receptor status, M0; ASTRO: ≥60 years, IDC, T1, N0, positive estrogen hormone receptor status, M0; TARGIT E “elderly”, risk adapted radiotherapy with IORT followed by external beam radiotherapy in case of risk factors in final histopathology. Consecutive patients operated on with the same surgical technique and given IORT were included. Wound complications were evaluated.

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