NAD+-dependent glutamate dehydrogenase of the edible mushroom Agaricus bisporus: biochemical and molecular characterization

1999 ◽  
Vol 261 (3) ◽  
pp. 452-462 ◽  
Author(s):  
M. A. S. H. Kersten ◽  
Y. Müller ◽  
J. J. P. Baars ◽  
H. J. M. Op den Camp ◽  
C. van der Drift ◽  
...  
Keyword(s):  
Glutamate Dehydrogenase ◽  
Molecular Characterization ◽  
Agaricus Bisporus ◽  
Edible Mushroom

Molecular characterization of the glnA gene encoding glutamine synthetase from the edible mushroom Agaricus bisporus

1997 ◽  
Vol 256 (2) ◽  
pp. 179-186 ◽  
Author(s):  
M. A. S. H. Kersten ◽  
Y. Müller ◽  
H. J. M. Op den Camp ◽  
G. D. Vogels ◽  
L. J. L. D. Van Griensven ◽  
...  
Keyword(s):  
Glutamine Synthetase ◽  
Molecular Characterization ◽  
Agaricus Bisporus ◽  
Edible Mushroom ◽  
Gene Encoding

scholarly journals Effect of polyvalencies of glycotopes on the binding of a lectin from the edible mushroom, Agaricus bisporus

2003 ◽  
Vol 371 (2) ◽  
pp. 311-320 ◽  
Author(s):  
Albert M. WU ◽  
June H. WU ◽  
Anthony HERP ◽  
Jia-Hau LIU
Keyword(s):  
Agaricus Bisporus ◽  
Therapeutic Potential ◽  
Specific Binding ◽  
Biological Activities ◽  
Edible Mushroom ◽  
Structural Requirement ◽  
Colon Cells ◽  
Lectin Receptor ◽  
Proliferative Effect ◽  
Potent Factor

Agaricus bisporus agglutinin (ABA) isolated from edible mushroom has a potent anti-proliferative effect on malignant colon cells with considerable therapeutic potential as an anti-neoplastic agent. Since previous studies on the structural requirement for binding were limited to molecular or submolecular levels of Galβ1-3GalNAc (T; Thomsen–Friedenreich disaccharide glycotope; where Gal represents d-galactopyranose and GalNAc represents 2-acetamido-2-deoxy-d-galactopyranose) and its derivatives, the binding properties of ABA were further investigated using our collection of glycans by enzyme-linked lectinosorbent assay and lectin–glycan inhibition assay. The results indicate that polyvalent Galβ1-related glycotopes, GalNAcα1-Ser/Thr (Tn), and their cryptoforms, are the most potent factor for ABA binding. They were up to 5.5×105 and 4.7×106 times more active than monomeric T and GalNAc respectively. The affinity of ABA for ligands can be ranked as: multivalent Tα (Galβ1-3GalNAcα1-), Tn and I/II (Galβ1-3GlcNac/Galβ1-4GlcNAc, where GlcNAc represents 2-acetamido-2-deoxy-d-glucopyranose)>>>>monomeric Tα and Tn>I>>GalNAc>>>II, L (Galβ1-4Glc, where Glc represents d-glucopyranose) and Gal (inactive). These specific binding features of ABA establish the importance of affinity enhancement by high-density polyvalent (versus multiantennary I/II) glycotopes and facilitate our understanding of the lectin receptor recognition events relevant to its biological activities.

MOLECULAR ANALYSIS OF LIGNOCELLULOLYTIC ENZYMES OF THE EDIBLE MUSHROOM AGARICUS BISPORUS

1990 ◽  
pp. 659-666 ◽  
Author(s):  
D.A. Wood ◽  
C. Perry ◽  
C.F. Thurston ◽  
S.E. Matcham ◽  
K. Dudley ◽  
...  
Keyword(s):  
Molecular Analysis ◽  
Agaricus Bisporus ◽  
Edible Mushroom ◽  
Lignocellulolytic Enzymes

Antioxidant potential of edible mushroom ( Agaricus bisporus) protein hydrolysates and their ultrafiltration fractions

2017 ◽  
Vol 230 ◽  
pp. 58-67 ◽  
Author(s):  
Benard Muinde Kimatu ◽  
Liyan Zhao ◽  
Yuan Biao ◽  
Gaoxing Ma ◽  
Wenjian Yang ◽  
...  
Keyword(s):  
Agaricus Bisporus ◽  
Edible Mushroom ◽  
Protein Hydrolysates ◽  
Antioxidant Potential

scholarly journals Tolerance to Ammonia in the Common Edible Mushroom Induced in Vitro

HortScience ◽  
1991 ◽  
Vol 26 (2) ◽  
pp. 138-140
Author(s):  
C. Peter Romaine ◽  
Laurie Raid
Keyword(s):  
Agaricus Bisporus ◽  
Edible Mushroom ◽  
The Common ◽  
Hyphal Tip

Commercial strains of Agaricus bisporus (Lange) Imbach that were grown in vitro at 32C for 4 to 5 weeks on a medium containing 250 μg amantadine/ml followed by hyphal tip-culturing showed an enhanced tolerance of ammonia in the compost during cropping trials. Yield of mushrooms by a treated off-white strain (GSP-18) and a treated white strain (Marlowe-503) was higher in composts with elevated levels of ammonia (0.11% to 0.27%) than that of the untreated cultures. Tolerance was related to the ability of the treated cultures to grow vegetatively in the ammonia-enriched compost. Tolerance was expressed by the cultures for at least 14 months following induction.

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