Clinical significance of peritumoral lymphatic vessel density and lymphatic vessel invasion detected by D2-40 immunostaining in FIGO Ib1-IIa squamous cell cervical cancer

2012 ◽  
Vol 348 (3) ◽  
pp. 515-522 ◽  
Author(s):  
Ying Xiong ◽  
Li-Ping Cao ◽  
Hui-Lan Rao ◽  
Mu-Yan Cai ◽  
Li-Zhi Liang ◽  
...  
2012 ◽  
Vol 56 (5-6) ◽  
pp. 368
Author(s):  
Miroslaw Kozlowski ◽  
Wojciech Naumnik ◽  
Wojciech Laudanski ◽  
Robert Milewski ◽  
Lech Chyczewski ◽  
...  

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 5036-5036
Author(s):  
G. Sauer ◽  
T. Ach ◽  
C. Kurzeder ◽  
J. Windisch ◽  
R. Kreienberg ◽  
...  

2010 ◽  
Vol 20 (7) ◽  
pp. 1225-1231 ◽  
Author(s):  
Fabricia L. Zaganelli ◽  
Filomena M. Carvalho ◽  
Bernardo G.L. Almeida ◽  
Carlos E. Bacchi ◽  
Joao Carlos Sampaio Goes ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
C. Balsat ◽  
S. Blacher ◽  
N. Signolle ◽  
A. Beliard ◽  
C. Munaut ◽  
...  

Peritumoral Lymphatic Vessel Density (LVD) is considered to be a predictive marker for the presence of lymph node metastases in cervical cancer. However, when LVD quantification relies on conventional optical microscopy and the hot spot technique, interobserver variability is significant and yields inconsistent conclusions. In this work, we describe an original method that applies computed image analysis to whole slide scanned tissue sections following immunohistochemical lymphatic vessel staining. This procedure allows to determine an objective LVD quantification as well as the lymphatic vessel distribution and its heterogeneity within the stroma surrounding the invasive tumor bundles. The proposed technique can be useful to better characterize lymphatic vessel interactions with tumor cells and could potentially impact on prognosis and therapeutic decisions.


2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 5036-5036
Author(s):  
G. Sauer ◽  
T. Ach ◽  
C. Kurzeder ◽  
J. Windisch ◽  
R. Kreienberg ◽  
...  

2016 ◽  
Vol 212 (12) ◽  
pp. 1095-1101 ◽  
Author(s):  
Jamile Marinho Bezerra de Oliveira Moura ◽  
Adriana Costa de Souza Martins Câmara ◽  
Cassiano Francisco Weege Nonaka ◽  
Leão Pereira Pinto ◽  
Lélia Batista de Souza

Sign in / Sign up

Export Citation Format

Share Document