Experimental renal progenitor cells: Repairing and recreating kidneys?

2013 ◽  
Vol 29 (4) ◽  
pp. 665-672 ◽  
Author(s):  
Paul J. D. Winyard ◽  
Karen L. Price
Keyword(s):  
Progenitor Cells ◽  
Renal Progenitor Cells ◽  
Renal Progenitor

Kidney bioengineering by using decellularized kidney scaffold and renal progenitor cells

2021 ◽  
pp. 101699
Author(s):  
Chih-Yang Hsu ◽  
Pei-Ling Chi ◽  
Hsin-Yu Chen ◽  
Shih-Hsiang Ou ◽  
Kang-Ju Chou ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Renal Progenitor Cells ◽  
Renal Progenitor

scholarly journals Sall1 balances self-renewal and differentiation of renal progenitor cells

Development ◽  
2014 ◽  
Vol 141 (5) ◽  
pp. 1047-1058 ◽  
Author(s):  
J. M. Basta ◽  
L. Robbins ◽  
S. M. Kiefer ◽  
D. Dorsett ◽  
M. Rauchman
Keyword(s):  
Progenitor Cells ◽  
Self Renewal ◽  
Renal Progenitor Cells ◽  
Renal Progenitor

scholarly journals Role of bone marrow-derived stem cells, renal progenitor cells and stem cell factor in chronic renal allograft nephropathy

2013 ◽  
Vol 49 (3) ◽  
pp. 235-247
Author(s):  
Hayam Abdel Meguid El Aggan ◽  
Mona Abdel Kader Salem ◽  
Nahla Mohamed Gamal Farahat ◽  
Ahmad Fathy El-Koraie ◽  
Ghaly Abd Al-Rahim Mohammed Kotb
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Stem Cell ◽  
Progenitor Cells ◽  
Stem Cell Factor ◽  
Renal Allograft ◽  
Renal Progenitor Cells ◽  
Renal Progenitor

scholarly journals miR-1915 and miR-1225-5p Regulate the Expression of CD133, PAX2 and TLR2 in Adult Renal Progenitor Cells

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e68296 ◽  
Author(s):  
Fabio Sallustio ◽  
Grazia Serino ◽  
Vincenzo Costantino ◽  
Claudia Curci ◽  
Sharon N. Cox ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Renal Progenitor Cells ◽  
Renal Progenitor

scholarly journals Renal Progenitor Cells Have Higher Genetic Stability and Lower Oxidative Stress than Mesenchymal Stem Cells during In Vitro Expansion

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Elís Rosélia Dutra de Freitas Siqueira Silva ◽  
Napoleão Martins Argôlo Neto ◽  
Dayseanny de Oliveira Bezerra ◽  
Sandra Maria Mendes de Moura Dantas ◽  
Lucilene dos Santos Silva ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Stem Cells ◽  
Dna Damage ◽  
Mesenchymal Stem Cells ◽  
Progenitor Cells ◽  
Genetic Stability ◽  
Renal Progenitor Cells ◽  
In Vitro Expansion ◽  
Renal Progenitor

In vitro senescence of multipotent cells has been commonly associated with DNA damage induced by oxidative stress. These changes may vary according to the sources of production and the studied lineages, which raises questions about the effect of growing time on genetic stability. This study is aimed at evaluating the evolution of genetic stability, viability, and oxidative stress of bone marrow mesenchymal stem cells (MSCBMsu) and renal progenitor cells of the renal cortex (RPCsu) of swine (Sus scrofa domesticus) in culture passages. P2, P5, and P9 were used for MSCBMsu and P1, P2, and P3 for RPCsu obtained by thawing. The experimental groups were submitted to MTT, apoptosis and necrosis assays, comet test, and reactive substance measurements of thiobarbituric acid (TBARS), nitrite, reduced glutathione (GSH), and catalase. The MTT test curve showed a mean viability of 1.14±0.62 and 1.12±0.54, respectively, for MSCBMsu and RPCsu. The percentages of MSCBMsu and RPCsu were presented, respectively, for apoptosis, an irregular and descending behavior, and necrosis, ascending and irregular. The DNA damage index showed higher intensity among the MSCBMsu in the P5 and P9 passages (p<0.05). In the TBARS evaluation, there was variation among the lines of RPCsu and MSCBMsu, presenting the last most significant variations (p<0.05). In the nitrite values, we identified only among the lines, in the passages P1 and P2, with the highest averages displayed by the MSCBMsu lineage (p<0.05). The measurement of antioxidant system activity showed high standards, identifying differences only for GSH values, in the RPCsu lineage, in P3 (p<0.05). This study suggests that the maintenance of cell culture in the long term induces lower regulation of oxidative stress, and RPCsu presents higher genetic stability and lower oxidative stress than MSCBMsu during in vitro expansion.

scholarly journals SaO032PAPILLARY RENAL CELL CARCINOMA ORIGINATES FROM A POPULATION OF RENAL PROGENITOR CELLS AND IS PROMOTED BY ACUTE KIDNEY INJURY

2018 ◽  
Vol 33 (suppl_1) ◽  
pp. i328-i328
Author(s):  
Anna Peired ◽  
Giulia Antonelli ◽  
Maria Lucia Angelotti ◽  
Alessandro Sisti ◽  
Marco Allinovi ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Acute Kidney Injury ◽  
Cell Carcinoma ◽  
Progenitor Cells ◽  
Renal Cell ◽  
Kidney Injury ◽  
Renal Progenitor Cells ◽  
Renal Progenitor
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