Modifiable factors and cognitive dysfunction in breast cancer survivors: a mixed-method systematic review

2015 ◽  
Vol 24 (1) ◽  
pp. 481-497 ◽  
Author(s):  
Ashley Henneghan
Cancers ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 107
Author(s):  
Kirsti Toivonen ◽  
Tamara Williamson ◽  
Linda Carlson ◽  
Lauren Walker ◽  
Tavis Campbell

Adjuvant endocrine therapy (AET) reduces risk of breast cancer recurrence. However, suboptimal adherence and persistence to AET remain important clinical issues. Understanding factors associated with adherence may help inform efforts to improve use of AET as prescribed. The present systematic review examined potentially modifiable factors associated with adherence to AET in accordance with PRISMA guidelines (PROSPERO registration ID: CRD42019124200). All studies were included, whether factors were significantly associated with adherence or results were null. This review also accounted for the frequency with which a potentially modifiable factor was examined and whether univariate or multivariate models were used. This review also examined whether methodological or sample characteristics were associated with the likelihood of a factor being associated with AET adherence. A total of 68 articles were included. Potentially modifiable factors were grouped into six categories: side effects, attitudes toward AET, psychological factors, healthcare provider-related factors, sociocultural factors, and general/quality of life factors. Side effects were less likely to be associated with adherence in studies with retrospective or cross-sectional than prospective designs. Self-efficacy (psychological factor) and positive decisional balance (attitude toward AET) were the only potentially modifiable factors examined ≥10 times and associated with adherence or persistence ≥75% of the time in both univariate and multivariate models. Self-efficacy and decisional balance (i.e., weight of pros vs. cons) were the potentially modifiable factors most consistently associated with adherence, and hence may be worth focusing on as targets for interventions to improve AET adherence among breast cancer survivors.


2021 ◽  
Vol 9 (2) ◽  
pp. 27
Author(s):  
Katherine Jinghua Lin ◽  
Cecile Lengacher ◽  
Carmen Rodriguez ◽  
Laura Szalacha ◽  
Jennifer Wolgemuth

2017 ◽  
Vol 53 (8) ◽  
pp. 504-512 ◽  
Author(s):  
Sarah E Neil-Sztramko ◽  
Kerri M Winters-Stone ◽  
Kelcey A Bland ◽  
Kristin L Campbell

ObjectivesTo update our previous evaluation of the exercise interventions used in randomised controlled trials of breast cancer survivors in relation to (1) the application of the principles of exercise training in the exercise prescription; (2) the reporting of the components of the exercise prescription; and (3) the reporting of adherence of participants to the prescribed interventions.DesignSystematic review.Data sourcesThe OVID Medline, Embase, CINAHL and SPORTDiscus electronic databases were searched from January 2010 to January 2017.Eligibility criteriaRandomised controlled trials of at least 4 weeks of aerobic and/or resistance exercise in women diagnosed with breast cancer, reporting on physical fitness or body composition outcomes.ResultsSpecificity was appropriately applied by 84%, progression by 29%, overload by 38% and initial values by 67% of newly identified studies. Reversibility was reported by 3% anddiminishing returns by 22% of newly identified studies. No studies reported all components of the exercise prescription in the methods, or adherence to the prescribed intervention in the results. Reporting of reversibility has increased from 2010, but no other improvements in reporting were noted from the previous review.Summary/ConclusionNo studies of exercise in women with breast cancer attended to all principles of exercise training, or reported all components of the exercise prescription in the methods, or adherence to the prescription in the results. Full reporting of the exercise prescribed and completed is essential for study replication in research and translating research findings into the community, and should be prioritised in future trials.


2012 ◽  
Vol 134 (2) ◽  
pp. 459-478 ◽  
Author(s):  
Caitlin C. Murphy ◽  
L. Kay Bartholomew ◽  
Melissa Y. Carpentier ◽  
Shirley M. Bluethmann ◽  
Sally W. Vernon

Author(s):  
Leidy Sofía Montaño-Rojas ◽  
Ena Monserrat Romero-Pérez ◽  
Carlos Medina-Pérez ◽  
María Mercedes Reguera-García ◽  
José Antonio de Paz

The aim of this study was to identify the characteristics of resistance training (RT) programs for breast cancer survivors (BCS). A systematic review of the literature was performed using PubMed, Medline, Science Direct, the Cochrane Breast Cancer Specialised Register of the Cochrane Library, the Physiotherapy Evidence Database (PEDro), and Scopus, with the aim of identifying all published studies on RT and BCS from 1 January 1990 to 6 December 2019, using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The risk of bias in the studies was assessed using the revised Cochrane Risk of Bias tool (RoB 2.0). Sixteen trials were included for qualitative analysis. More than half of the trials do not adequately report the characteristics that make up the exercise program. The maximal strength was the most frequently monitored manifestation of strength, evaluated mainly as one-repetition maximum (1RM). Resistance training was performed on strength-training machines, twice a week, using a load between 50% and 80% of 1RM. The trials reported significant improvement in muscle strength, fatigue, pain, quality of life, and minor changes in aerobic capacity.


2020 ◽  
Vol 180 (1) ◽  
pp. 1-19 ◽  
Author(s):  
Akemi T. Wijayabahu ◽  
Kathleen M. Egan ◽  
Lusine Yaghjyan

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