Health-related quality of life of thyroid cancer patients undergoing radioiodine therapy: a cohort real-world study in a reference public cancer hospital in Brazil

2019 ◽  
Vol 28 (8) ◽  
pp. 3771-3779
Author(s):  
Jayda Eiras Ramim ◽  
Marcella Araugio Soares Cardoso ◽  
Gessen Lopes Carneiro de Oliveira ◽  
Maria Luisa Gomes ◽  
Tiago Teixeira Guimarães ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Cancer Patients ◽  
Real World ◽  
Radioiodine Therapy ◽  
Health Related Quality ◽  
Cancer Hospital ◽  
Related Quality ◽  
Health Related

scholarly journals Health Related Quality of Life of Thyroid Cancer Patients

2020 ◽  
Vol 38 (2) ◽  
pp. 1-8
Author(s):  
AKM Farhad Hossain ◽  
Md Ziaul Islam ◽  
Sayada Fatema Khatun
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Cancer Patients ◽  
Clinical Condition ◽  
Family Income ◽  
Health Related Quality ◽  
Hrqol Score ◽  
Related Quality ◽  
Health Related

Background: Having the longevity of thyroid cancer patients, any impairment in health-related quality of life (HRQOL) during the follow-up period is of great importance. Objective: The study was conducted to determine the health related quality of life of thyroid cancer patients. Material and methods: This cross sectional study was conducted among 246thyroid cancer patients. Data were collected by face-to-face interview and reviewing medical records with semi-structured questionnaire and checklist with validated scale. The subjects were purposively selected following specific selection criteria and maintaining ethical issues. Place and period of study: The study was conducted during the period from July 2018-June 2019 in two tertiary hospitals of Dhaka city: Bangabandhu Sheikh Mujib Medical University and Dhaka Medical College Hospital, Dhaka. Results: This study revealed that majority (74.4%) of respondents was female, married (72%), housewife (61.4%), rural respondent (41.1%) and had primary education (69%). Mean (± SD) age of the respondent was 37.85(±12.20) years (range 14-70 years) and mean (± SD) monthly family income was Tk.17681(±10602). Out of 246 cases, 204 (82.9%) was papillary and 42 (17.1%) was follicular carcinoma. Main presenting features were neck swelling (91.5%), swollen lymph node (41.9%), dysphonia (57.3%) and dysphagia (35.4%). Mean (± SD) of total HRQOL score was 73.7 ± 8.39. HRQOL score of students and higher educated patients were better among the respective groups (p <.001). The study showed the association of HRQOL with clinical condition of thyroid cancer patients (R2=.025). HRQOL revealed the strong prediction with education (β=-0.888, p<.05), family income (β=0.05, p<.05), marital status (β=-0.1.384, p<.05), clinical condition (β=-0.522, p<.05) and perceived stress (β=-0.632, p<.001). Conclusion: The overall HRQOL score was considerably good in this study. Timely detection, regular motivation and attending clinical condition may significantly improve the HRQOL of thyroid cancer patients JOPSOM 2019; 38(2): 1-8

Health-related Quality of Life, Depression and Anxiety in Thyroid Cancer Patients

2006 ◽  
Vol 15 (4) ◽  
pp. 695-703 ◽  
Author(s):  
Sefik Tagay ◽  
Stephan Herpertz ◽  
Matthias Langkafel ◽  
Yesim Erim ◽  
Andreas Bockisch ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Cancer Patients ◽  
Depression And Anxiety ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Health-related quality of life, anxiety and depression in thyroid cancer patients under short-term hypothyroidism and TSH-suppressive levothyroxine treatment

2005 ◽  
Vol 153 (6) ◽  
pp. 755-763 ◽  
Author(s):  
Sefik Tagay ◽  
Stephan Herpertz ◽  
Matthias Langkafel ◽  
Yesim Erim ◽  
Lutz Freudenberg ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Radioiodine Therapy ◽  
Anxiety And Depression ◽  
Health Related Quality ◽  
Short Term ◽  
Related Quality ◽  
Health Related ◽  
Levothyroxine Treatment

Objective: Very few previous studies have compared the degree of health-related quality of life (HRQL), depression and anxiety of differentiated thyroid cancer patients (DTC) under short-term hypothyroid-ism and levothyroxine treatment. Methods: Using patient-completed instruments, we examined the frequency of physical complaints, HRQL, anxiety and depression in 130 DTC patients hospitalized for radioiodine therapy or whole-body diagnostics (age 52 years, female 71%) under short-term hypothyroidism (4 weeks of levothyroxine withdrawal; DTC-H) and in 100 DTC out-patients under TSH-suppressive doses of levothyroxine subsequent to radioiodine therapy (DTC-L; age 49 years, female 81%). Results: Compared with the German general population, DTC-H as well as DTC-L patients had significantly impaired HRQL. Notably, the decrease in HRQL was significantly higher in DTC-H than in DTC-L patients. Surprisingly, the prevalence of anxiety (44.6%) but not depression (17.7%) was much higher in the DTC-H patients than in the general population. In contrast to expectations, similar results for anxiety (44.0%) and depression (17.6%) were observed in the DTC-L patients. Conclusions: This mounting evidence suggests that a consistent pattern of HRQL impairment is experienced by patients with DTC. The high frequency of anxiety and the significantly reduced HRQL should be considered in the aftercare of DTC patients.

scholarly journals Exploring the relationship among dispositional optimism, health-related quality of life, and CIPN severity among colorectal cancer patients with chronic peripheral neuropathy

2021 ◽  
Author(s):  
Hester.R. Trompetter ◽  
Cynthia S. Bonhof ◽  
Lonneke V. van de Poll-Franse ◽  
Gerard Vreugdenhil ◽  
Floortje Mols
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Peripheral Neuropathy ◽  
Cancer Patients ◽  
Anxiety Symptoms ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract Purpose Chemotherapy-induced peripheral neuropathy ((CI)PN) becomes chronic in 30% of cancer patients. Knowledge of predictors of chronic (CI)PN and related impairments in health-related quality of life (HRQoL) is lacking. We examined the role of optimism in chronic (CI)PN severity and associated HRQoL in colorectal cancer (CRC) patients up to two years after diagnosis. Methods CRC patients from a prospective cohort study participated, with sensory peripheral neuropathy (SPN) 1 year after diagnosis (n = 142). Multivariable regression analyses examined the cross-sectional association between optimism (measured by the LOT-R) and SPN severity/HRQoL (measured by the EORTC QLQ-CIPN20 and QLQ-C30), as well as the prospective association in a subsample that completed measures 2 years after diagnosis and still experienced SPN (n = 86). Results At 1-year follow-up, higher optimism was associated with better global HRQoL, and better physical, role, emotional, cognitive, and social functioning (all p < .01). Optimism at year one was also prospectively associated with better global HRQoL (p < .05), and emotional and cognitive functioning at 2-year follow-up (both p < .01). Optimism was not related to self-reported SPN severity. Significant associations were retained when controlling for demographic/clinical variables, and became non-significant after controlling for depressive and anxiety symptoms. Conclusions Optimism and depressive and anxiety symptoms are associated with HRQoL in CRC patients with chronic (CI)PN. Future research may illuminate the mechanisms that these factors share, like the use of (non)adaptive coping styles such as avoidance and acceptance that may inform the design of targeted interventions to help patients to adapt to chronic (CI)PN.

scholarly journals Health-Related Quality of Life in Asian Differentiated Thyroid Cancer Survivors

2021 ◽  
Vol 28 ◽  
pp. 107327482110297
Author(s):  
Wing-Lok Chan ◽  
Horace Cheuk-Wai Choi ◽  
Brian Lang ◽  
Kai-Pun Wong ◽  
Kwok-Keung Yuen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Cancer Survivors ◽  
Differentiated Thyroid Cancer ◽  
Summary Score ◽  
Health Related Quality ◽  
Factors Associated ◽  
Related Quality ◽  
Health Related

Background: Health-related quality of life (HRQoL) is important for differentiated thyroid cancer survivors, but data for Asian survivors is lacking. This study aimed to have an overview of, and identify any disease-or treatment-related factors associated with, HRQoL in Asian differentiated thyroid cancer survivors. Patients and Methods: Thyroid cancer survivors were recruited from the thyroid clinics at Queen Mary Hospital, Hong Kong from February 2016 to December 2016. All adult differentiated thyroid cancer patients with stable disease more than or equal to 1 year received a survey on HRQoL using the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and Thyroid cancer specific quality of life (THYCA-QoL) questionnaire. Clinical information was collected retrospectively from the computerized clinical management system. To identify factors associated with poor HRQoL, univariable and stepwise multivariable regression analysis were performed. Results: A total of 613 survivors completed the questionnaires (response rate: 82.1%; female: 80.1%; median survivorship: 7.4 years (range: 1.0-48.2 years)). The QLQ-C30 summary score mean was 84.4 (standard deviation (SD): 12.7) while the THYCA-QoL summary score mean was 39.9 (SD: 9.7). The 2 highest symptom subscales were fatigue (mean: 26.4, SD: 20.6) and insomnia (mean: 26.2, SD: 27.6). Factors associated with worse HRQoL included serum thyrotropin (TSH) greater than 1.0 mIU/L, unemployment, and concomitant psychiatric disorders. Concomitant psychiatric illness (n = 40/613, 6.5%) also showed significant association with most of the symptom and functional subscales. Conclusions: Fatigue and insomnia were the 2 most common symptoms experienced by our differentiated thyroid cancer survivors. Long-term survivorship care with monitoring serum TSH level, supporting return-to-work and screening for concomitant psychiatric disorders should be offered.

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