scholarly journals High-intensity interval training in the prehabilitation of cancer patients—a systematic review and meta-analysis

2020 ◽  
Author(s):  
Stefano Palma ◽  
Timothy Hasenoehrl ◽  
Galateja Jordakieva ◽  
Dariga Ramazanova ◽  
Richard Crevenna
Keyword(s):  
Systematic Review ◽  
Cancer Patients ◽  
High Intensity ◽  
Meta Analysis ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Randomized Controlled ◽  
Health Related ◽  
High Intensity Interval ◽  
The Impact

Abstract Purpose To evaluate the impact of high-intensity interval training (HIIT) on health-related outcome parameters in the prehabilitation of patients diagnosed with cancer. Methods A systematic review and meta-analysis of comparative studies on HIIT in cancer prehabilitation conducted by screening standard databases from their inception to March 30, 2020. Outcomes of interest included cardiorespiratory fitness, feasibility, safety, clinical, and patient-reported outcomes. Results Of the 855 identified studies, 8 articles met the inclusion criteria (7 randomized, 1 non-randomized controlled trial) with a total of 896 patients. The study protocols were heterogeneous, but the methodological quality ranged from good to high according to PEDro scale. Meta-analysis revealed a significant improvement of peak oxygen consumption (VO2peak) achieved with HIIT compared to usual care. Furthermore, HIIT was feasible and safe, showing low risk of adverse events and positive effects on health-related outcomes in prehabilitative settings. Conclusion In the phase of prehabilitation, HIIT has potential health benefits in patients diagnosed with cancer and is feasible and safe to perform. Nonetheless, larger randomized controlled trials focusing on long-term effects (such as cancer recurrence or survival rates) are missing, to underline the potential relevance of HIIT for cancer patients.

High-intensity interval training in the therapy and aftercare of cancer patients: a systematic review with meta-analysis

2019 ◽  
Vol 13 (2) ◽  
pp. 205-223 ◽  
Author(s):  
Hendrik Mugele ◽  
Nils Freitag ◽  
Jannik Wilhelmi ◽  
Yanxiang Yang ◽  
Sulin Cheng ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cancer Patients ◽  
High Intensity ◽  
Meta Analysis ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval

scholarly journals Effect of high-intensity interval training on metabolic parameters in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials

PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0245023
Author(s):  
Isis Kelly dos Santos ◽  
Fernando Antônio Santana de Souza Nunes ◽  
Victor Sabino Queiros ◽  
Ricardo Ney Cobucci ◽  
Pedro Bruch Dantas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Insulin Resistance ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Interval Training ◽  
Controlled Trials ◽  
High Intensity Interval Training ◽  
Ovary Syndrome ◽  
Randomized Controlled ◽  
High Intensity Interval

Background Our aim was to assess the effect of high-intensity interval training (HIIT) on metabolic parameters and body composition in women with polycystic ovary syndrome (PCOS). Methods and analysis A systematic review and meta-analysis of randomized controlled trials was conducted using Embase, MEDLINE (via Ovid), PubMed, Sport Discus, Scopus, Web of Science, Cochrane Library and Google Scholar (advanced feature) up to September 2020. Two authors independently screened citations and determined the risk of bias and quality of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Meta-analyses were conducted using random effects model. Results Seven trials (n = 423) were included in the systematic review. The studies included HIIT interventions vs. moderate exercise or control groups. Most studies were small (average 32, range 24–110 participants) and of relatively short duration (10–16 weeks). The training intensity was performed between 90% and 95% of the maximum heart rate, three times a week, for at least 10 weeks. Insulin resistance, measured using homeostatic model assessment for insulin resistance (HOMA-IR), and body mass index (BMI) showed a significant decrease (MD −0.57; 95% CI, −0.98 to −0.16, p = 0.01), (MD −1.90, 95% CI −3.37, −0.42, p = 0.01) with moderate and high certainty of evidence, respectively. Conclusion Results support that HIIT alone is effective for reducing HOMA-IR and BMI in women with PCOS. However, evidence is limited to discern the effect of HIIT on other outcomes. Future studies with a longer duration (> 16 weeks), larger sample sizes and other outcomes are needed.

scholarly journals The Effect of Beetroot Ingestion on High-Intensity Interval Training: A Systematic Review and Meta-Analysis

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3674
Author(s):  
Tak Hiong Wong ◽  
Alexiaa Sim ◽  
Stephen F. Burns
Keyword(s):  
Systematic Review ◽  
Power Output ◽  
High Intensity ◽  
Meta Analysis ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Mean Power ◽  
Nitrate Supplementation ◽  
High Intensity Interval ◽  
Mean Power Output

Dietary nitrate supplementation has shown promising ergogenic effects on endurance exercise. However, at present there is no systematic analysis evaluating the effects of acute or chronic nitrate supplementation on performance measures during high-intensity interval training (HIIT) and sprint interval training (SIT). The main aim of this systematic review and meta-analysis was to evaluate the evidence for supplementation of dietary beetroot—a common source of nitrate—to improve peak and mean power output during HIIT and SIT. A systematic literature search was carried out following PRISMA guidelines and the PICOS framework within the following databases: PubMed, ProQuest, ScienceDirect, and SPORTDiscus. Search terms used were: ((nitrate OR nitrite OR beetroot) AND (HIIT or high intensity or sprint interval or SIT) AND (performance)). A total of 17 studies were included and reviewed independently. Seven studies applied an acute supplementation strategy and ten studies applied chronic supplementation. The standardised mean difference for mean power output showed an overall trivial, non-significant effect in favour of placebo (Hedges’ g = −0.05, 95% CI −0.32 to 0.21, Z = 0.39, p = 0.69). The standardised mean difference for peak power output showed a trivial, non-significant effect in favour of the beetroot juice intervention (Hedges’ g = 0.08, 95% CI -0.14 to 0.30, Z = 0.72, p = 0.47). The present meta-analysis showed trivial statistical heterogeneity in power output, but the variation in the exercise protocols, nitrate dosage, type of beetroot products, supplementation strategy, and duration among studies restricted a firm conclusion of the effect of beetroot supplementation on HIIT performance. Our findings suggest that beetroot supplementation offers no significant improvement to peak or mean power output during HIIT or SIT. Future research could further examine the ergogenic potential by optimising the beetroot supplementation strategy in terms of dosage, timing, and type of beetroot product. The potential combined effect of other ingredients in the beetroot products should not be undermined. Finally, a chronic supplementation protocol with a higher beetroot dosage (>12.9 mmol/day for 6 days) is recommended for future HIIT and SIT study.

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