Venous thromboembolism after esophagectomy for cancer: a systematic review of the literature to evaluate incidence, risk factors, and prophylaxis

Surgery Today ◽  
2021 ◽  
Author(s):  
Nikoletta A. Theochari ◽  
Christina A. Theochari ◽  
Damianos G. Kokkinidis ◽  
Aristotelis Kechagias ◽  
Orestis Lyros ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Venous Thromboembolism ◽  
Review Of The Literature ◽  
Incidence Risk ◽  
Esophagectomy For Cancer

scholarly journals Incidence, risk factors and prognostic effect of imaging right ventricular involvement in patients with COVID-19: a dose–response analysis protocol for systematic review

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e049866
Author(s):  
Chenghui Zhou ◽  
Baohui Lou ◽  
Hui Li ◽  
Xin Wang ◽  
Hushan Ao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Right Ventricular ◽  
Dose Response ◽  
Meta Analysis ◽  
Adult Patients ◽  
Sensitivity Analyses ◽  
Prognostic Effect ◽  
All Cause Mortality ◽  
Incidence Risk

IntroductionEmerging evidence has shown that COVID-19 infection may result in right ventricular (RV) disturbance and be associated with adverse clinical outcomes. The aim of this meta-analysis is to summarise the incidence, risk factors and the prognostic effect of imaging RV involvement in adult patients with COVID-19.MethodsA systematical search will be performed in PubMed, EMBase, ISI Knowledge via Web of Science and preprint databases (MedRxiv and BioRxiv) (until October 2021) to identify all cohort studies in adult patients with COVID-19. The primary outcome will be the incidence of RV involvement (dysfunction and/or dilation) assessed by echocardiography, CT or MRI. Secondary outcomes will include the risk factors for RV involvement and their association with all-cause mortality during hospitalisation. Additional outcomes will include the RV global or free wall longitudinal strain (RV-GLS or RV-FWLS), tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC) and RV diameter. Univariable or multivariable meta-regression and subgroup analyses will be performed for the study design and patient characteristics (especially acute or chronic pulmonary embolism and pulmonary hypertension). Sensitivity analyses will be used to assess the robustness of our results by removing each included study at one time to obtain and evaluate the remaining overall estimates of RV involvement incidence and related risk factors, association with all-cause mortality, and other RV parameters (RV-GLS or RV-FWLS, TAPSE, S’, FAC and RV diameter). Both linear and cubic spline regression models will be used to explore the dose–response relationship between different categories (>2) of RV involvement and the risk of mortality (OR or HR).Ethics and disseminationThere was no need for ethics approval for the systematic review protocol according to the Institutional Review Board/Independent Ethics Committee of Fuwai Hospital. This meta-analysis will be disseminated through a peer-reviewed journal for publication.PROSPERO registration numberCRD42021231689.

scholarly journals Psoriasis and Vascular Disease—Risk Factors and Outcomes: A Systematic Review of the Literature

2011 ◽  
Vol 26 (9) ◽  
pp. 1036-1049 ◽  
Author(s):  
Rita V. Patel ◽  
Michael L. Shelling ◽  
Srdjan Prodanovich ◽  
Daniel G. Federman ◽  
Robert S. Kirsner
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Vascular Disease ◽  
Disease Risk ◽  
Review Of The Literature

Implications of cytogenetics for venous thromboembolism in acute myeloid leukaemia

2015 ◽  
Vol 113 (01) ◽  
pp. 201-208 ◽  
Author(s):  
Ji-hyun Kwon ◽  
Sung Yoon ◽  
Leo Song ◽  
Jae-Ho Yoon ◽  
Seung-Hwan Shin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Advanced Age ◽  
Leukemia Diagnosis ◽  
Incidence Risk ◽  
Thrombotic Complications ◽  
Predictive Role ◽  
Independent Risk Factors ◽  
One Year ◽  
Acute Myeloid

SummaryDue to the high risk of thrombocytopenia and haemorrhage, thrombotic complications have received little attention in patients with acute myeloid leukemia (AML). Furthermore, the predictive role of cytogenetics on venous thromboembolism (VTE) has largely been ignored. This study aimed to evaluate the incidence, risk factors, and prognostic aspects of VTE in AML. A total of 811 consecutive patients with AML were enrolled and analysed retrospectively. Cox time-dependent covariate regression analysis was used to identify the significant predictors of VTE development. To minimise potential confounding factors, we used propensity-score matching to compare overall survival between patients with and without VTE. The six-month and one-year cumulative incidences of VTE were 3.1 % (95 % confidence interval [CI], 2.0–4.7) and 3.9 % (95 % CI, 2.6–5.7), respectively. Of the 26 cases of VTE, 22 (85 %) developed within 6 months of leukemia diagnosis and 13 (50 %) were catheter-related. In multivariate analysis, advanced age (≥ 65 years) (hazard ratio [HR], 2.70; p = 0.03) and increasing cytogenetic risk (common HR, 1.84; p = 0.05) were independent predictors of VTE. There was no significant association between VTE development and decreased survival (p = 0.32 for matched analysis). Advanced age and increasing cytogenetic risk, well-known predictors for clinical outcome in AML, were also independent risk factors of VTE development. Our results suggest that VTE does not hold prognostic implications for AML.

scholarly journals Risk Factors of Peptic Ulcer in Military Personnel: A Systematic Review of the Literature

2020 ◽  
Vol 000 (000) ◽  
pp. 1-7
Author(s):  
Chunmei Wang ◽  
Xiaozhong Guo ◽  
Yang An ◽  
Shixue Xu ◽  
Dan Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Peptic Ulcer ◽  
Military Personnel ◽  
Review Of The Literature

Pathophysiology of telangiectasias of the lower legs and its therapeutic implication: A systematic review

2018 ◽  
Vol 33 (4) ◽  
pp. 225-233 ◽  
Author(s):  
P Kern
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Current Knowledge ◽  
Clinical Perspective ◽  
Review Of The Literature ◽  
Venous Plexus ◽  
Treatment Results ◽  
Therapeutic Implications ◽  
Improve Treatment ◽  
Tissue Abnormalities

Objective Telangiectasias of the lower legs are intradermal dilatations of the subpapillary venous plexus, but their pathophysiology and risk factors are still largely unknown. The purpose of this review is to summarize the current knowledge on the pathophysiology and risk factors for telangiectasias. Methods A systematic review of the literature indexed in Medline completed with textbooks and European phlebology journals from the French, Swiss, and German phlebology societies was performed. Results A multitude of risk factors and several pathophysiological hypotheses, such as reflux, arterio-venous micro-shunts, parietal, and connective tissue abnormalities, are described in the literature. The different hypotheses are discussed and put in a clinical perspective, in particular their therapeutic implications for phlebologists. Conclusion In conclusion, pathophysiology and risk factors of telangiectasias are still largely unknown, and a better understanding could improve treatment results and reduce recurrence.

Sign in / Sign up

Export Citation Format

Share Document