The role of band structure in Co- and Fe-co-doped Ba0.5Sr0.5Zr0.1Y0.1O3-δ perovskite semiconductor to design an electrochemical aptasensing platform: application in label-free detection of ochratoxin A using voltammetry

2021 ◽  
Vol 188 (5) ◽  
Author(s):  
Sajid Rauf ◽  
Maryam Awan ◽  
Naveed Rauf ◽  
Zuhra Tayyab ◽  
Nasir Ali ◽  
...  
Keyword(s):  
Band Structure ◽  
Ochratoxin A ◽  
Label Free ◽  
Label Free Detection ◽  
Co Doped

scholarly journals The Role of Surface Chemistry in the Efficacy of Protein and DNA Microarrays for Label-Free Detection: An Overview

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1026
Author(s):  
Elisa Chiodi ◽  
Allison M. Marn ◽  
Matthew T. Geib ◽  
M. Selim Ünlü
Keyword(s):  
Surface Chemistry ◽  
Surface Functionalization ◽  
Dna Microarrays ◽  
Label Free ◽  
Polymeric Coatings ◽  
Label Free Detection ◽  
Particle Imaging ◽  
Single Particle Imaging ◽  
The Impact

The importance of microarrays in diagnostics and medicine has drastically increased in the last few years. Nevertheless, the efficiency of a microarray-based assay intrinsically depends on the density and functionality of the biorecognition elements immobilized onto each sensor spot. Recently, researchers have put effort into developing new functionalization strategies and technologies which provide efficient immobilization and stability of any sort of molecule. Here, we present an overview of the most widely used methods of surface functionalization of microarray substrates, as well as the most recent advances in the field, and compare their performance in terms of optimal immobilization of the bioreceptor molecules. We focus on label-free microarrays and, in particular, we aim to describe the impact of surface chemistry on two types of microarray-based sensors: microarrays for single particle imaging and for label-free measurements of binding kinetics. Both protein and DNA microarrays are taken into consideration, and the effect of different polymeric coatings on the molecules’ functionalities is critically analyzed.

Rapid and label-free detection of ochratoxin A and aflatoxin B1 using an optical portable instrument

Talanta ◽  
2016 ◽  
Vol 150 ◽  
pp. 440-448 ◽  
Author(s):  
Fabiana Arduini ◽  
Daniela Neagu ◽  
Valeria Pagliarini ◽  
Viviana Scognamiglio ◽  
Maria Antonietta Leonardis ◽  
...  
Keyword(s):  
Ochratoxin A ◽  
Aflatoxin B1 ◽  
Portable Instrument ◽  
Label Free ◽  
Label Free Detection

Thioacetamide-derived nitrogen and sulfur co-doped carbon nanoparticles used for label-free detection of copper(ii) ions and bioimaging applications

2017 ◽  
Vol 41 (22) ◽  
pp. 13742-13746 ◽  
Author(s):  
Hari Krishna Sadhanala ◽  
Ananya Maddegalla ◽  
K. K. Nanda
Keyword(s):  
Carbon Nanoparticles ◽  
Label Free ◽  
Efficient Detection ◽  
Label Free Detection ◽  
Co Doped

Thioacetamide-derived nitrogen and sulfur co-doped carbon nanoparticles as photoluminescent probes for the efficient detection of Cu2+ ions.

scholarly journals Label-free detection of creatinine using nitrogen-passivated fluorescent carbon dots

RSC Advances ◽  
2020 ◽  
Vol 10 (60) ◽  
pp. 36253-36264
Author(s):  
Shagun Kainth ◽  
Banibrata Maity ◽  
Soumen Basu
Keyword(s):  
Carbon Dots ◽  
Label Free ◽  
Label Free Detection ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

The role of passivation in CDs using different nitrogen precursors to evaluate its sensing proficiency towards creatinine quantification.

scholarly journals Spectral-Phase Interferometry Detection of Ochratoxin A via Aptamer-Functionalized Graphene Coated Glass

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 226
Author(s):  
Nikita Nekrasov ◽  
Natalya Yakunina ◽  
Averyan V. Pushkarev ◽  
Alexey V. Orlov ◽  
Ivana Gadjanski ◽  
...  
Keyword(s):  
Small Molecules ◽  
Ochratoxin A ◽  
Direct Method ◽  
Low Cost ◽  
Optical Signal ◽  
Spectral Phase ◽  
Urea Solution ◽  
Label Free ◽  
Label Free Detection ◽  
Interferometric Sensor

In this work, we report a novel method of label-free detection of small molecules based on direct observation of interferometric signal change in graphene-modified glasses. The interferometric sensor chips are fabricated via a conventional wet transfer method of CVD-grown graphene onto the glass coverslips, lowering the device cost and allowing for upscaling the sensor fabrication. For the first time, we report the use of graphene functionalized by the aptamer as the bioreceptor, in conjunction with Spectral-Phase Interferometry (SPI) for detection of ochratoxin A (OTA). In a direct assay with an OTA-specific aptamer, we demonstrated a quick and significant change of the optical signal in response to the maximum tolerable level of OTA concentration. The sensor regeneration is possible in urea solution. The developed platform enables a direct method of kinetic analysis of small molecules using a low-cost optical chip with a graphene-aptamer sensing layer.

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