Association of transforming growth factor-β1 gene C509T, G800A and T869C polymorphisms with intracerebral hemorrhage in North Indian Population: a case–control study

2015 ◽  
Vol 37 (3) ◽  
pp. 353-359 ◽  
Author(s):  
Pradeep Kumar ◽  
Amit Kumar ◽  
Shubham Misra ◽  
Ram Sagar ◽  
Mohammad Farooq ◽  
...  
Keyword(s):  
Growth Factor ◽  
Intracerebral Hemorrhage ◽  
Indian Population ◽  
Case Control Study ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Case Control ◽  
North Indian Population ◽  
Control Study

Serum transforming growth factor-β1 levels and pancreatic cancer risk: a nested case–control study (Japan)

2006 ◽  
Vol 17 (8) ◽  
pp. 1077-1082 ◽  
Author(s):  
Yingsong Lin ◽  
Shogo Kikuchi ◽  
Akiko Tamakoshi ◽  
Yuki Obata ◽  
Kiyoko Yagyu ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Growth Factor ◽  
Cancer Risk ◽  
Case Control Study ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Case Control ◽  
Pancreatic Cancer Risk ◽  
Nested Case Control ◽  
Control Study

Transforming Growth Factor-α and Nonsyndromic Cleft Lip with or without Palate in Brazilian Patients: Results of a Large Case-Control Study

2004 ◽  
Vol 41 (4) ◽  
pp. 387-391 ◽  
Author(s):  
Maria Rita Passos-Bueno ◽  
Dinamar A. Gaspar ◽  
Tânia Kamiya ◽  
Graziela Tescarollo ◽  
Daniel Rabanéa ◽  
...  
Keyword(s):  
Growth Factor ◽  
Cleft Lip ◽  
Case Control Study ◽  
Transforming Growth Factor ◽  
Case Control ◽  
Genotype Distribution ◽  
Chi Square ◽  
Transforming Growth Factor Α ◽  
Factor Α ◽  
Control Study

Objective Transforming growth factor-α (TGFA) was the first gene suggested to be associated with nonsyndromic cleft lip, cleft palate, or both (CL/ P). There are, however, still controversies of the effect of TGFA on the predisposition of this malformation. To contribute to a better understanding of the role of this gene in the occurrence of CL/P we undertook a case-control study including patients and controls ascertained in different regions of the country. Design We examined the C2/TaqI variant of the TGFA gene in 536 patients with nonsyndromic CL/P and 412 controls. The TGFA genotype frequencies in patients were compared with controls using chi-square or Fisher exact test. DNA, obtained from peripheral blood or buccal swabs, was genotyped for the TaqI polymorphism of TGFA. Setting The probands and corresponding controls were ascertained in different centers of Brazil, partly representing the ethnic admixture of our population. Results The TGFA genotype distribution was very similar in patients with CL/P ascertained in the three different regions of Brazil. However, a discrete difference was observed between controls of Säo Paulo and Ceará (chi-square = 3.605; p = 0.058), with a lower value of the C2/Taq allele frequency in controls of CE (0.04). These data reinforce that this polymorphic system is heterogenous among different ethnic groups. In addition, no evidence was found for an association of TGFA with CL/P in this case-control study. Conclusion These data further suggest that TGFA is not a relevant modifier locus for the occurrence of CL/P.

scholarly journals PDE4D Gene Polymorphisms and Coronary Heart Disease: A Case-Control Study in a North Indian Population

2013 ◽  
Vol 27 (4) ◽  
pp. 297-300 ◽  
Author(s):  
Ekata Sinha ◽  
Sanjenbam Yaiphaba Meitei ◽  
Priyanka Rani Garg ◽  
Kallur Nava Saraswathy
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Gene Polymorphisms ◽  
Indian Population ◽  
Case Control Study ◽  
Case Control ◽  
North Indian Population ◽  
Control Study
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