Serum transforming growth factor-β1 levels and pancreatic cancer risk: a nested case–control study (Japan)

2006 ◽  
Vol 17 (8) ◽  
pp. 1077-1082 ◽  
Author(s):  
Yingsong Lin ◽  
Shogo Kikuchi ◽  
Akiko Tamakoshi ◽  
Yuki Obata ◽  
Kiyoko Yagyu ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Growth Factor ◽  
Cancer Risk ◽  
Case Control Study ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Case Control ◽  
Pancreatic Cancer Risk ◽  
Nested Case Control ◽  
Control Study

scholarly journals A Prospective Nested Case-Control Study of Vitamin D Status and Pancreatic Cancer Risk in Male Smokers

2006 ◽  
Vol 66 (20) ◽  
pp. 10213-10219 ◽  
Author(s):  
Rachael Z. Stolzenberg-Solomon ◽  
Reinhold Vieth ◽  
Azar Azad ◽  
Pirjo Pietinen ◽  
Philip R. Taylor ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Vitamin D ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Vitamin D Status ◽  
Pancreatic Cancer Risk ◽  
Nested Case Control ◽  
Control Study

Statins and pancreatic cancer risk: a nested case–control study

2010 ◽  
Vol 21 (12) ◽  
pp. 2093-2100 ◽  
Author(s):  
Marie C. Bradley ◽  
Carmel M. Hughes ◽  
Marie M. Cantwell ◽  
Liam J. Murray
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Pancreatic Cancer Risk ◽  
Nested Case Control ◽  
Control Study

scholarly journals Non-steroidal anti-inflammatory drugs and pancreatic cancer risk: a nested case–control study

2010 ◽  
Vol 102 (9) ◽  
pp. 1415-1421 ◽  
Author(s):  
M C Bradley ◽  
C M Hughes ◽  
M M Cantwell ◽  
G Napolitano ◽  
L J Murray
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Pancreatic Cancer Risk ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Nested Case Control ◽  
Control Study

scholarly journals DNA methylation derived immune cell profiles, CpG markers of inflammation, and pancreatic cancer risk

2020 ◽  
Author(s):  
Dominique S. Michaud ◽  
Mengyuan Ruan ◽  
Devin C. Koestler ◽  
Lola Alonso ◽  
Esther Molina-Montes ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Dna Methylation ◽  
Cancer Risk ◽  
Case Control Study ◽  
Immune Cell ◽  
Case Control ◽  
Pancreatic Cancer Risk ◽  
Markers Of Inflammation ◽  
Nested Case Control ◽  
Control Study

AbstractPancreatic cancer is projected to become the second most common cause of cancer death over the next 5 years. Since inflammation is thought to be a common trajectory for disease initiation, we sought to prospectively characterize immune profiles using DNA methylation markers to examine whether they play a key role in pancreatic cancer risk. In a nested case-control study pooling three U.S. prospective cohort studies, DNA methylation was measured in prediagnostic leukocytes of incident pancreatic cancer cases and matched controls using the Illumina MethylationEPIC array. Differentially methylated regions were used to predict immune cell types and CpGs previously associated with blood inflammatory markers were selected for the analysis. DNA methylation data from a retrospective case-control study conducted in Spain (PanGenEU) was used for independent replication of results. Immune cell proportions and ratio of cell proportions were not associated with pancreatic cancer risk in the nested case-control study. Methylation extent of CpGs residing in or near gene MNDA was significantly associated with pancreatic cancer risk in the nested case-control study and replicated in PanGenEU. In the nested case-control study, the associations were present 10 or more years prior to cancer diagnosis. Methylation of a promoter CpG of gene PIM-1 was associated with pancreatic cancer survival in both studies. We identified several CpGs that may play a role in pancreatic carcinogenesis using a targeted approach for the selection of inflammation-based CpGs in two large, independent studies conducted in different countries with distinct study designs.

Assessing the effects of beta‐blockers on pancreatic cancer risk: A nested case‐control study

2020 ◽  
Vol 29 (5) ◽  
pp. 599-604
Author(s):  
Akram Saad ◽  
Jeffrey Goldstein ◽  
Ofer Margalit ◽  
Einat Shacham‐Shmueli ◽  
Yaacov R. Lawrence ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Beta Blockers ◽  
Case Control ◽  
Pancreatic Cancer Risk ◽  
Nested Case Control ◽  
Control Study

scholarly journals Trajectories of physical activity, from young adulthood to older adulthood, and pancreatic cancer risk; a population-based case-control study in Ontario, Canada

BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jaspreet Sandhu ◽  
Vanessa De Rubeis ◽  
Michelle Cotterchio ◽  
Brendan T. Smith ◽  
Lauren E. Griffith ◽  
...  
Keyword(s):  
Physical Activity ◽  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Young Adulthood ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Older Adulthood ◽  
Pancreatic Cancer Risk ◽  
Control Study

scholarly journals Association between Alcohol Consumption and Pancreatic Cancer Risk: A Case-Control Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0124489 ◽  
Author(s):  
Farah Rahman ◽  
Michelle Cotterchio ◽  
Sean P. Cleary ◽  
Steven Gallinger
Keyword(s):  
Pancreatic Cancer ◽  
Alcohol Consumption ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Pancreatic Cancer Risk ◽  
Control Study

scholarly journals Trajectories of body mass index, from adolescence to older adulthood, and pancreatic cancer risk; a population-based case–control study in Ontario, Canada

2019 ◽  
Vol 30 (9) ◽  
pp. 955-966 ◽  
Author(s):  
Vanessa De Rubeis ◽  
Michelle Cotterchio ◽  
Brendan T. Smith ◽  
Lauren E. Griffith ◽  
Ayelet Borgida ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Body Mass Index ◽  
Cancer Risk ◽  
Body Mass ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Older Adulthood ◽  
Pancreatic Cancer Risk ◽  
Control Study
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