A voxel-based lesion symptom mapping analysis of chronic pain in multiple sclerosis

2020 ◽  
Author(s):  
Domenico Plantone ◽  
Catello Vollono ◽  
Matteo Pardini ◽  
Guido Primiano ◽  
Virxhina Myftari ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Chronic Pain ◽  
Mapping Analysis ◽  
Lesion Symptom Mapping

Neural Correlates of Hiccups in Patients with Lateral Medullary Infarction

2021 ◽  
pp. 097275312110237
Author(s):  
Appaswamy Thirumal Prabhakar ◽  
Tephilah Rabi ◽  
Atif I. A. Shaikh ◽  
Sanjith Aaron ◽  
Rohit Benjamin ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Neural Correlates ◽  
Permutation Testing ◽  
Resonance Imaging ◽  
Lateral Medullary Infarction ◽  
Lateral Region ◽  
Mapping Analysis ◽  
Lesion Symptom Mapping ◽  
The Brain ◽  
Medullary Infarction

Background Hiccups is a known presentation of lateral medullary infarction. However, the region in the medulla associated with this finding is not clearly known. In this study, we aimed to study the neural correlates of hiccups in patients with lateral medullary infarction (LMI). Materials and Methods This retrospective study included all patients who presented with lateral medullary infarction between January 2008 and May 2018. Patients with hiccups following LMI were identified as cases and those with no hiccups but who had LMI were taken as controls. The magnetic resonance imaging of the brain was done viewed and individual lesions were mapped manually to the template brain. Voxel-based lesion-symptom mapping employing nonparametric permutation testing was performed using MRIcron. Results There were a total of 31 patients with LMI who presented to the hospital during the study period. There were 11 (35.5%) patients with hiccups. Using the voxel-based lesion-symptom mapping analysis, the dorso-lateral region of the middle medulla showed significant association with hiccups. Conclusion In patients with LMI, we postulate that damage to the dorsolateral aspect on the middle medulla could result in hiccups.

Multiple Sclerosis and Pain: A Medical Focus

2000 ◽  
Vol 2 (3) ◽  
pp. 40-47 ◽  
Author(s):  
Marilyn Kassirer
Keyword(s):  
Multiple Sclerosis ◽  
Chronic Pain ◽  
Joint Pain ◽  
Pain Syndrome ◽  
Surgical Interventions ◽  
Alternative Interventions ◽  
Pain Syndromes ◽  
Drug Treatments ◽  
Patients Experience ◽  
Iatrogenic Pain

Abstract About 65% of multiple sclerosis (MS) patients experience a broad range of both acute and subacute painful syndromes. Acute conditions (eg, trigeminal neuralgia and Lhermitte's syndrome) cause intense, unrelenting pain that may worsen with age and disease progression. Chronic pain (eg, joint pain) is also a component of MS. Pain syndromes, including optic neuritis, complex regional pain syndrome (CRPS), and other less well-known syndromes, may respond to a variety of pharmacologic, surgical, or alternative interventions. MS patients may also experience iatrogenic pain. Some successful drug treatments for pain that are used in combination or alone include anticonvulsants, tricyclics, methylprednisolone, and narcotics. Surgical interventions, percutaneous compression-balloons, and radiofrequency ablation are other viable options for some pain syndromes.

scholarly journals A Comparison of Self-Hypnosis Versus Progressive Muscle Relaxation in Patients With Multiple Sclerosis and Chronic Pain

2009 ◽  
Vol 57 (2) ◽  
pp. 198-221 ◽  
Author(s):  
Mark P. Jensen ◽  
Joseph Barber ◽  
Joan M. Romano ◽  
Ivan R. Molton ◽  
Katherine A. Raichle ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Chronic Pain ◽  
Muscle Relaxation ◽  
Progressive Muscle Relaxation

scholarly journals Chronic Pain in Multiple Sclerosis: An Overview

2014 ◽  
Vol 2 (2) ◽  
pp. 20 ◽  
Author(s):  
A. R. M. Saifuddin Ekram
Keyword(s):  
Multiple Sclerosis ◽  
Chronic Pain

Positive affect, resilience, and function in adults with multiple sclerosis and chronic pain

2018 ◽  
Vol 19 (3) ◽  
pp. S32 ◽  
Author(s):  
A. Arewasikporn ◽  
A. Turner ◽  
K. Alschuler ◽  
D. Ehde ◽  
M. Jensen
Keyword(s):  
Multiple Sclerosis ◽  
Chronic Pain ◽  
Positive Affect ◽  
And Function
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