Clinical utility of home videos for diagnosing epileptic seizures: a systematic review and practical recommendations for optimal and safe recording

: The widespread adoption of endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms (AAA) is due to the obvious advantages of the procedure compared to the traditional open repair. However, these advantages have to be weighed against the increased risk of renal dysfunction with EVAR. The evaluation of the perioperative renal function after EVAR has been hampered by the lack of sensitive and specific biochemical markers of acute kidney injury (AKI). The purpose of this study was to summarize all novel renal biomarkers and to evaluate their clinical utility for the assessment of the kidney function after EVAR. A systematic review of the current literature, as the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guidelines, was performed to identify relevant studies with novel renal biomarkers and EVAR. Pubmed and Scopus databases were systemically searched. Studies reporting on thoracic endovascular aortic repair (TEVAR), case reports, case series, letters to the editor, and systematic reviews were excluded. Neutrophil-Gelatinase-Associated Lipocalin, Cystatin C, Liver-type fatty-acid-binding protein were the most common among the eligible studies while Interleukin-18, Retinol binding protein, N-acetyle-b-D-glucosaminidase and microalbumin have a sparse appearance in the literature. These biomarkers have been assessed in plasma as well as urine samples with each sample material having its own advantages and drawbacks. Which of these biomarkers has the most potential for assessing postoperative renal failure after EVAR, remains to be proved. The few studies presented in the literature show the potential clinical utility of these biomarkers, but larger studies with longer follow-up are required to determine the precise relationship between these biomarkers and postoperative acute kidney injury.

Download Full-text

The Clinical Utility of Virtual Reality in Neurorehabilitation: A Systematic Review

Journal of Central Nervous System Disease ◽

10.1177/1179573518813541 ◽

2018 ◽

Vol 10 ◽

pp. 117957351881354 ◽

Cited By ~ 25

Author(s):

Thais Massetti ◽

Talita Dias da Silva ◽

Tânia Brusque Crocetta ◽

Regiani Guarnieri ◽

Bruna Leal de Freitas ◽

...

Keyword(s):

Systematic Review ◽

Virtual Reality ◽

Virtual Environments ◽

Neurological Disorders ◽

Clinical Utility ◽

Spinal Cord Injuries ◽

Web Of Science ◽

The Past ◽

Meta Analyses ◽

The Impact

Background: Virtual reality (VR) experiences (through games and virtual environments) are increasingly being used in physical, cognitive, and psychological interventions. However, the impact of VR as an approach to rehabilitation is not fully understood, and its advantages over traditional rehabilitation techniques are yet to be established. Method: We present a systematic review which was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). During February and March of 2018, we conducted searches on PubMed (Medline), Virtual Health Library Search Portal databases (BVS), Web of Science (WOS), and Embase for all VR-related publications in the past 4 years (2015, 2016, 2017, and 2018). The keywords used in the search were “neurorehabilitation” AND “Virtual Reality” AND “devices.” Results: We summarize the literature which highlights that a range of effective VR approaches are available. Studies identified were conducted with poststroke patients, patients with cerebral palsy, spinal cord injuries, and other pathologies. Healthy populations have been used in the development and testing of VR approaches meant to be used in the future by people with neurological disorders. A range of benefits were associated with VR interventions, including improvement in motor functions, greater community participation, and improved psychological and cognitive function. Conclusions: The results from this review provide support for the use of VR as part of a neurorehabilitation program in maximizing recovery.

Download Full-text

Clinical utility of B-type natriuretic peptide (NP) in pediatric cardiac surgery - a systematic review

Pediatric Anesthesia ◽

10.1111/pan.12467 ◽

2014 ◽

Vol 25 (2) ◽

pp. 115-126 ◽

Cited By ~ 5

Author(s):

Nura Afshani ◽

Simone Schülein ◽

Bruce M. Biccard ◽

Jenny M. Thomas

Keyword(s):

Systematic Review ◽

Cardiac Surgery ◽

Natriuretic Peptide ◽

Clinical Utility ◽

Pediatric Cardiac Surgery

Download Full-text

CT densitometry in emphysema: a systematic review of its clinical utility

International Journal of Chronic Obstructive Pulmonary Disease ◽

10.2147/copd.s143066 ◽

2018 ◽

Vol Volume 13 ◽

pp. 547-563 ◽

Cited By ~ 12

Author(s):

Diana Crossley ◽

Mary Renton ◽

Muhammad Khan ◽

Emma V Low ◽

Alice M Turner

Keyword(s):

Systematic Review ◽

Clinical Utility

Download Full-text

Clinical Utility of Intravascular Ultrasound (IVUS) in Carotid Artery Interventions: A Systematic Review and Meta-analysis

Journal of Endovascular Therapy ◽

10.1177/15266028211064824 ◽

2021 ◽

pp. 152660282110648

Author(s):

B. Mishra ◽

A. K. Pandit ◽

S. Miyachi ◽

T. Ohshima ◽

R. Kawaguchi ◽

...

Keyword(s):

Systematic Review ◽

Carotid Artery ◽

Intravascular Ultrasound ◽

Clinical Utility ◽

English Literature ◽

Meta Analysis ◽

Randomized Controlled Studies ◽

Stent Type ◽

Pooled Prevalence ◽

Practice Parameters

Background: Carotid plaque morphology plays an important role in determining outcome of carotid artery stenting (CAS). Intravascular ultrasound (IVUS) and its extension VH (Virtual Histology)-IVUS evaluate plaque characteristics in real time and guide decision making during stenting. To date, there is no consensus about indications of IVUS and its validated methods. This systematic review and meta-analysis aims to evaluate the clinical utility of IVUS in carotid artery interventions (CAS) and develop a future consensus for research and practice parameters. Methods: A systematic review and meta-analysis was performed of the English literature articles published till February 2021. Studies reporting on IVUS parameters and findings and also its performance compared with other imaging modalities were included in review. Pooled prevalence with 95% confidence intervals (CI) was calculated. The statistical analysis was conducted in R version 3.6.2. Results: A total of 2015 patients from 29 studies were included. Proportional meta-analysis was performed on 1566 patients from 11 studies. In 9 studies, stroke/transient ischemic attack (TIA) had a pooled prevalence of 4% (95% CI 3%–5%) while asymptomatic stroke had a pooled prevalence of 46% (95% CI 31%–62%) in 4 studies following IVUS. Two studies reported that IVUS detected more plaque protrusion compared with angiography (n=33/396 vs 11/396). IVUS led to stent type or size change in 8 of 48 cases which were missed on angiography in 3 other studies. Concordance between VH-IVUS and true histology was good at 80% to 85% reported in 2 studies. Conclusions: This systematic review and meta-analysis showed, though IVUS fared better to computed tomography (CT)/magnetic resonance (MR) angiography for better stent selection during CAS, with low to moderate risk of bias in the studies included. However, large scale, preferably randomized controlled studies are needed to predict its role in determining clinical outcome.

Download Full-text

Medical technology: A systematic review on medical devices utilized for epilepsy prediction and management

Current Neuropharmacology ◽

10.2174/1570159x19666211108153001 ◽

2021 ◽

Vol 19 ◽

Author(s):

Jen Sze Ong ◽

Shuet Nee Wong ◽

Alina Arulsamy ◽

Jessica L. Watterson ◽

Mohd. Farooq Shaikh

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Medical Devices ◽

Epileptic Seizures ◽

Well Being ◽

Sudden Unexpected Death ◽

Unexpected Death ◽

Long Time ◽

Wearable Medical

: Epilepsy is a devastating neurological disorder that affects nearly 70 million people worldwide. Epilepsy causes uncontrollable, unprovoked and unpredictable seizures that reduces the quality of life of those afflicted, with 1-9 epileptic patient deaths per 1000 patient occurring annually due to sudden unexpected death in epilepsy (SUDEP). Predicting the onset of seizures and managing them may help patients from harming themselves and may improve their well-being. For a long time, electroencephalography (EEG) devices have been the mainstay for seizure detection and monitoring. This systematic review aimed to elucidate and critically evaluate the latest advancements of medical devices, besides EEG, that have been proposed for the management and prediction of epileptic seizures. A literature search was performed on three databases; PubMed, Scopus and EMBASE. Following title/abstract screening by two independent reviewers, 27 articles were selected for critical analysis in this review. These articles revealed ambulatory, non-invasive and wearable medical devices such as the in-ear EEG devices, the accelerometer-based devices and the subcutaneous implanted EEG devices might be more acceptable than traditional EEG systems. In addition, extracerebral signal-based devices may be more efficient than EEG-based systems, especially when combined with an intervention trigger. Although further studies may still be required to improve and validate these proposed systems before commercialization, these findings may give hope to epileptic patients, particularly those with refractory epilepsy, to predict and manage their seizures. The use of medical devices for epilepsy may improve patients' independence and quality of life and possibly prevent sudden unexpected death in epilepsy (SUDEP).

Download Full-text

Epileptic seizures in patients with COVID-19: A systematic review of early evidences

Journal of Biomedical Sciences ◽

10.3126/jbs.v8i1.38459 ◽

2021 ◽

Vol 8 (1) ◽

pp. 33-44

Author(s):

B Roy ◽

I Banerjee

Keyword(s):

Systematic Review ◽

Epileptic Seizure ◽

Case Reports ◽

Neurological Complication ◽

Epileptic Seizures ◽

Neurological Complications ◽

Cross Sectional Study ◽

Cerebrovascular Diseases ◽

Cross Sectional ◽

Demyelinating Lesions

Background: Global emergence of SARS-CoV-2 surfaced neurological complications amongst the patients. COVID-19 resembles with other coronavirus strains follows a trend of neurological complication, damage and encephalopathy, which entails considerable risks, requires attention for the neurologists. This is, to our knowledge, the first systematic review of the literature to investigate solely to elucidate the seizure spectrum by unfolding epileptogenicity of the SARS CoV-2 and potential pathways of neuroinvasion. Methods: A systematic literature search was performed in PubMed and Embase database following standard guidelines, using specific keywords based on epileptic seizure onset described from December 01, 2019, to July 17, 2020 Results: A total of 17 studies were included ranging from case reports, series of cases, multicentre cross-sectional study with the first-time onset of seizure associated with an epileptic origin. We excavated causes of complex COVID-19 related neurological manifestations, e.g., cerebrovascular diseases, encephalitis, demyelinating lesions, cytokine storm and proposed routes of SARS-CoV-2 entry into the nervous system to understand the mechanism of an epileptic seizure. Conclusion: COVID-19 is a potent neuropathogen which causes the new onset of epileptic seizures should get diagnostic recognition to evade possible deterioration of neurological conditions. However, more shreds of evidence from the future will further elucidate the epileptogenic potential of the pandemic.

Download Full-text