Variable abnormality of the melanopsin-derived portion of the pupillary light reflex (PLR) in patients with Parkinson’s disease (PD) and parkinsonism features

2021 ◽  
Author(s):  
Bruce I. Gaynes ◽  
Adnaan Zaffer ◽  
Raman Yousefzai ◽  
Mario Chazaro-Cortes ◽  
Kalea Colletta ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Pupillary Light Reflex ◽  
Light Reflex ◽  
Pupillary Light

scholarly journals Effect of Topical Anti-Glaucoma Medications on Late Pupillary Light Reflex, as Evaluated by Pupillometry

2015 ◽  
Vol 6 ◽  
Author(s):  
Shakoor Ba-Ali ◽  
Birgit Sander ◽  
Adam Elias Brøndsted ◽  
Henrik Lund-Andersen
Keyword(s):  
Pupillary Light Reflex ◽  
Light Reflex ◽  
Pupillary Light

scholarly journals Relationship between Human Pupillary Light Reflex and Circadian System Status

PLoS ONE ◽  
2016 ◽  
Vol 11 (9) ◽  
pp. e0162476 ◽  
Author(s):  
Maria Angeles Bonmati-Carrion ◽  
Konstanze Hild ◽  
Cheryl Isherwood ◽  
Stephen J. Sweeney ◽  
Victoria L. Revell ◽  
...  
Keyword(s):  
Circadian System ◽  
Pupillary Light Reflex ◽  
Light Reflex ◽  
Pupillary Light

scholarly journals A role for the ciliary marginal zone in the melanopsin-dependent intrinsic pupillary light reflex

2014 ◽  
Vol 119 ◽  
pp. 8-18 ◽  
Author(s):  
Ma'ayan Semo ◽  
Carlos Gias ◽  
Ahmad Ahmado ◽  
Anthony Vugler
Keyword(s):  
Marginal Zone ◽  
Pupillary Light Reflex ◽  
Light Reflex ◽  
Pupillary Light ◽  
Ciliary Marginal Zone

scholarly journals Pupillary Light Reflex is Altered in Adolescent Depression

2017 ◽  
pp. S277-S284 ◽  
Author(s):  
A. MESTANIKOVA ◽  
I. ONDREJKA ◽  
M. MESTANIK ◽  
D. CESNEKOVA ◽  
Z. VISNOVCOVA ◽  
...  
Keyword(s):  
Nervous System ◽  
Major Depression ◽  
Parasympathetic Nervous System ◽  
Dynamic Balance ◽  
Pupillary Light Reflex ◽  
Control Group ◽  
Light Reflex ◽  
Pupillary Light ◽  
Adolescent Patients ◽  
Depressive Group

Major depressive disorder is associated with abnormal autonomic regulation which could be noninvasively studied using pupillometry. However, the studies in adolescent patients are rare. Therefore, we aimed to study the pupillary light reflex (PLR), which could provide novel important information about dynamic balance between sympathetic and parasympathetic nervous system in adolescent patients suffering from major depression. We have examined 25 depressive adolescent girls (age 15.2±0.3 year) prior to pharmacotherapy and 25 age/gender-matched healthy subjects. PLR parameters were measured separately for both eyes after 5 min of rest using Pupillometer PLR-2000 (NeurOptics, USA). The constriction percentual change for the left eye was significantly lower in depressive group compared to control group (-24.12±0.87 % vs. –28.04±0.96%, p˂0.01). Furthermore, average constriction velocity and maximum constriction velocity for the left eye were significantly lower in depressive group compared to control group (p˂0.05, p˂0.01, respectively). In contrast, no significant between-groups differences were found for the right eye. Concluding, this study revealed altered PLR for left eye indicating a deficient parasympathetic activity already in adolescent major depression. Additionally, the differences between left and right eye could be related to functional lateralization of autonomic control in the central nervous system.

The pupillary light reflex pathway: Cytoarchitectonic probabilistic maps in hemianopic patients

Neurology ◽  
2008 ◽  
Vol 70 (12) ◽  
pp. 956-963 ◽  
Author(s):  
E. Papageorgiou ◽  
L. F. Ticini ◽  
G. Hardiess ◽  
F. Schaeffel ◽  
H. Wiethoelter ◽  
...  
Keyword(s):  
Pupillary Light Reflex ◽  
Reflex Pathway ◽  
Light Reflex ◽  
Pupillary Light ◽  
Probabilistic Maps
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