Prevalence and molecular diversity of invasive Streptococcus dysgalactiae and Streptococcus pyogenes in a German tertiary care medical centre

2018 ◽  
Vol 37 (7) ◽  
pp. 1325-1332
Author(s):  
S. Rößler ◽  
R. Berner ◽  
E. Jacobs ◽  
N. Toepfner
Keyword(s):  
Streptococcus Pyogenes ◽  
Molecular Diversity ◽  
Tertiary Care ◽  
Medical Centre ◽  
Streptococcus Dysgalactiae

Tumid lupus erythematosus and systemic lupus erythematosus: a rare coexistence

2021 ◽  
Vol 14 (10) ◽  
pp. e245196
Author(s):  
Ailia Ali ◽  
Alexander Woods ◽  
Caroline Porter ◽  
Steven R Feldman
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Tertiary Care ◽  
Medical Centre ◽  
Shortness Of Breath ◽  
Systemic Lupus

A patient diagnosed with tumid lupus erythematosus (TLE) was subsequently found to have systemic lupus erythematosus (SLE) after presenting to a tertiary care medical centre with shortness of breath and oedema. In this commentary, we discuss this patient’s presentation and the association between TLE and SLE.

scholarly journals Gene Repertoire Evolution of Streptococcus pyogenes Inferred from Phylogenomic Analysis with Streptococcus canis and Streptococcus dysgalactiae

PLoS ONE ◽  
2012 ◽  
Vol 7 (5) ◽  
pp. e37607 ◽  
Author(s):  
Tristan Lefébure ◽  
Vince P. Richards ◽  
Ping Lang ◽  
Paulina Pavinski-Bitar ◽  
Michael J. Stanhope
Keyword(s):  
Streptococcus Pyogenes ◽  
Phylogenomic Analysis ◽  
Gene Repertoire ◽  
Streptococcus Dysgalactiae ◽  
Streptococcus Canis

Patterns of Suicidal Poisoning Cases in Three Tertiary Care Government Hospitals in Karachi, Pakistan

2020 ◽  
Author(s):  
Lubna Riaz
Keyword(s):  
Tertiary Care ◽  
Conscious State ◽  
Young Female ◽  
Medical Centre ◽  
Southern District ◽  
Government Hospitals ◽  
Suicidal Attempts ◽  
Chi Squared ◽  
Past Data ◽  
Tertiary Care Hospitals

Background: Suicidal attempts are a global problem and their rate of incidence is increasing day by day. This study aimed to elucidate the patterns of suicidal poisoning cases presenting in three tertiary care government hospitals of Karachi, Pakistan. Methods: In this retrospective observational study, past data records of 627 suicidal (poisoning) cases of the three tertiary care hospitals of Karachi from a period of January 2016 to December 2016 were evaluated to see patterns of suicidal cases. Data was analyzed using SPSS version 25.0 via Chi-squared test. Results: Majority of the cases (36.4%) belonged to the 9-25 years’ age group. Mean age of the cases was 25:31 ± 9.92. Females (57.3%) considerably outnumbered males (42.7%). The greatest number of cases reported was from Southern district of Karachi (23%) followed by West (21.5%), central (20.9%) and East (11%) reported mainly at Jinnah Postgraduate Medical Centre. The most common poisoning agent used for suicidal attempts was insecticide (40.2%), followed by rodenticide (19.9%). Majority of patients were examined on the same day of attempting suicide (95.5%), majority were in conscious state (76.2%). Admission record for most cases was unmentioned. (66.3%) Conclusion: Majority of the cases presented at three tertiary care government hospitals who attempted suicide were young female adults mainly from South district of Karachi followed by West, Central and East Karachi. Pesticides, specifically, insecticides and rodenticides, were the most commonly used poisoning agents used for suicide. Majority of cases were brought at Jinnah Post Graduate Medical Centre in the conscious state.

Disease burden due to Streptococcus dysgalactiae subsp. equisimilis (group G and C streptococcus) is higher than that due to Streptococcus pyogenes among Mumbai school children

2010 ◽  
Vol 59 (2) ◽  
pp. 220-223 ◽  
Author(s):  
Pallaval V. Bramhachari ◽  
Santosh Y. Kaul ◽  
David J. McMillan ◽  
Melkote S. Shaila ◽  
Mohan G. Karmarkar ◽  
...  
Keyword(s):  
Streptococcus Pyogenes ◽  
Disease Burden ◽  
Group A Streptococcus ◽  
Genetic Material ◽  
Haemolytic Activity ◽  
Streptococcus Dysgalactiae ◽  
Carriage Rate ◽  
Municipal Schools ◽  
Group A ◽  
Rheumatic Heart

Streptococcus pyogenes [group A streptococcus (GAS)], a human pathogen, and Streptococcus dysgalactiae subsp. equisimilis [human group G and C streptococcus (GGS/GCS)] are evolutionarily related, share the same tissue niche in humans, exchange genetic material, share up to half of their virulence-associated genes and cause a similar spectrum of diseases. Yet, GGS/GCS is often considered as a commensal bacterium and its role in streptococcal disease burden is under-recognized. While reports of the recovery of GGS/GCS from normally sterile sites are increasing, studies describing GGS/GCS throat colonization rates relative to GAS in the same population are very few. This study was carried out in India where the burden of streptococcal diseases, including rheumatic fever and rheumatic heart disease, is high. As part of a surveillance study, throat swabs were taken from 1504 children attending 7 municipal schools in Mumbai, India, during 2006–2008. GAS and GGS/GCS were identified on the basis of β-haemolytic activity, carbohydrate group and PYR test, and were subsequently typed. The GGS/GCS carriage rate (166/1504, 11 %) was eightfold higher than the GAS carriage (22/1504, 1.5 %) rate in this population. The 166 GGS/GCS isolates collected represented 21 different emm types (molecular types), and the 22 GAS isolates represented 15 different emm types. Although the rate of pharyngitis associated with GGS/GCS is marginally lower than with GAS, high rates of throat colonization by GGS/GCS underscore its importance in the pathogenesis of pharyngitis.

scholarly journals Severe invasive streptococcal infection by Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

2016 ◽  
Vol 60 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Shinya Watanabe ◽  
Norihiko Takemoto ◽  
Kohei Ogura ◽  
Tohru Miyoshi-Akiyama
Keyword(s):  
Streptococcus Pyogenes ◽  
Streptococcal Infection ◽  
Streptococcus Dysgalactiae

scholarly journals Salivaricin G32, a Homolog of the PrototypeStreptococcus pyogenesNisin-Like Lantibiotic SA-FF22, Produced by the Commensal SpeciesStreptococcus salivarius

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Philip A. Wescombe ◽  
Kristin H. Dyet ◽  
Karen P. Dierksen ◽  
Daniel A. Power ◽  
Ralph W. Jack ◽  
...  
Keyword(s):  
Structural Gene ◽  
Streptococcus Pyogenes ◽  
Streptococcus Salivarius ◽  
Streptococcus Dysgalactiae ◽  
Inhibitory Peptide ◽  
Widespread Distribution ◽  
Human Host ◽  
Oral Microflora ◽  
Inhibitory Spectrum

Salivaricin G32, a 2667 Da novel member of the SA-FF22 cluster of lantibiotics, has been purified and characterized fromStreptococcus salivariusstrain G32. The inhibitory peptide differs from theStreptococcus pyogenes—produced SA-FF22 in the absence of lysine in position 2. The salivaricin G32 locus was widely distributed in BLIS-producingS. salivarius, with 6 (23%) of 26 strains PCR-positive for the structural gene,slnA. As for most other lantibiotics produced byS. salivarius, the salivaricin G32 locus can be megaplasmid encoded. Another member of the SA-FF22 family was detected in twoStreptococcus dysgalactiaeof bovine origin, an observation supportive of widespread distribution of this lantibiotic within the genusStreptococcus. Since the inhibitory spectrum of salivaricin G32 includesStreptococcus pyogenes, its production byS. salivarius, either as a member of the normal oral microflora or as a commercial probiotic, could serve to enhance protection of the human host againstS. pyogenesinfection.

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