scholarly journals The successful uptake and sustainability of rapid infectious disease and antimicrobial resistance point-of-care testing requires a complex ‘mix-and-match’ implementation package

2019 ◽  
Vol 38 (6) ◽  
pp. 1015-1022 ◽  
Author(s):  
John P. Hays ◽  
◽  
Konstantinos Mitsakakis ◽  
Saturnino Luz ◽  
Alex van Belkum ◽  
...  
2020 ◽  
Vol 144 (11) ◽  
pp. 1372-1380
Author(s):  
Mark Shephard ◽  
Anne Shephard ◽  
Susan Matthews ◽  
Kelly Andrewartha

Context.— Point-of-care (POC) testing has significant potential application in rural and remote Australian communities where access to laboratory-based pathology testing is often poor and the burden of chronic, acute, and infectious disease is high. Objective.— To explore the clinical, operational, cultural, and cost benefits of POC testing in the Australian rural and remote health sector and describe some of the current challenges and limitations of this technology. Data Sources.— Evidence-based research from established POC testing networks for chronic, acute, and infectious disease currently managed by the International Centre for Point-of-Care Testing at Flinders University are used to highlight the experience gained and the lessons learned from these networks and, where possible, describe innovative solutions to address the current barriers to the uptake of POC testing, which include governance, staff turnover, maintaining training and competency, connectivity, quality testing, sustainable funding mechanisms, and accreditation. Conclusions.— Point-of-care testing can provide practical and inventive opportunities to revolutionize the delivery of pathology services in rural and remote sectors where clinical need for this technology is greatest. However, many barriers to POC testing still exist in these settings, and the full potential of POC testing cannot be realized until these limitations are addressed and resolved.


Author(s):  
Daniel Berman

Antimicrobial resistance (AMR) is one of the most serious clinical and public healthcare challenges. In this video Daniel Berman,  Nesta Challenges, provides an overview of the Longitude Prize, why the prize was set up and what the prize hopes to achieve. Daniel also provides insight into some of the rapid diagnostic tests currently in the running for the £8 million prize.


2017 ◽  
Author(s):  
Emma Harding-Esch ◽  
Susie E Huntington ◽  
Mike Harvey ◽  
Claire E Broad ◽  
Elisabeth J Adams ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
pp. 6-12
Author(s):  
S. K. Yadav ◽  
S. K. Agrawal ◽  
S. K. Singh ◽  
A. Giri ◽  
G. K. Singh ◽  
...  

SETTING: Nobel Medical College and Teaching Hospital, Biratnagar, Nepal.OBJECTIVE: To determine the pattern of antimicrobial resistance and hospital exit outcomes in neonates with suspected sepsis in a tertiary neonatal intensive care unit (NICU).DESIGN: This hospital-based cohort study was conducted to follow patients from January to December 2019. All identified cases of suspected sepsis were enlisted from hospital records.RESULTS: Sepsis was suspected in 177 (88%) of the 200 cases admitted in the NICU; 52 (29%) were culture-positive. Pseudomonas was the predominant organism isolated (n = 40; 78%), followed by coagulase negative staphylococcus (n = 12, 23%). Nine (17%) of the 52 isolates were resistant to the Access and Watch group of antibiotics, including some resistance to Reserve group drugs such as imipenem and linezolid. Most treated cases (n = 170, 96%) improved, although 7 (4%) left against medical advice.CONCLUSION: Most of the pathogens were resistant to WHO Access and Watch antibiotics and occasional resistance was observed to Reserve group drugs. Most sepsis was caused by Gram-negative bacilli. Improving turnaround times for antibiotic sensitivity testing using point-of-care testing, and a greater yield of culture-positive results are needed to enhance the management of neonatal sepsis.


2017 ◽  
Vol 240 ◽  
pp. 881-886 ◽  
Author(s):  
Yuriko Oyama ◽  
Toshihisa Osaki ◽  
Koki Kamiya ◽  
Masatoshi Sawai ◽  
Masatoshi Sakai ◽  
...  

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