The impact of advanced age on short- and long-term results after surgery for colorectal cancer

Abstract Laparoscopic colorectal resection has been applied to advanced colorectal cancer. Synchronous liver metastasis of colorectal cancer would be treated safely and effectively by simultaneous laparoscopic colorectal and hepatic resection. Seven patients with colorectal cancer and synchronous liver metastasis treated by simultaneous laparoscopic resection were analyzed retrospectively. Three patients received a hybrid operation using a small skin incision, 2 patients underwent hand-assisted laparoscopic surgery using a small incision produced for colonic anastomosis, and 2 patients were treated with pure laparoscopic resection. The mean total operation duration was 407 minutes, and mean blood loss was 207 mL. Negative surgical margins were achieved in all cases. Mean postoperative hospital stay was 16.4 days. No recurrence at the surgical margin was observed in the liver. For selected patients with synchronous liver metastasis of colorectal cancer, simultaneous laparoscopic resection is useful for minimizing operative invasiveness while maintaining safety and curability, with satisfying short- and long-term results.

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Laparoscopic resection followed by decompression with a drainage tube for obstructive colorectal cancer.

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.4_suppl.844 ◽

2018 ◽

Vol 36 (4_suppl) ◽

pp. 844-844

Author(s):

Yoshinori Kagawa ◽

Kohei Murata ◽

Atsushi Naito ◽

Kenji Kawai ◽

Yutaka Takeda ◽

...

Keyword(s):

Colorectal Cancer ◽

Stent Placement ◽

Laparoscopic Resection ◽

Drainage Tube ◽

Stage Ii ◽

Long Term Results ◽

Metallic Stent ◽

Obstructive Colorectal Cancer ◽

Short And Long Term

844 Background: Obstructive colorectal cancer is an oncological emergency that requires emergency treatment. In Japan, laparoscopic resection after decompression with metallic-stent placement is becoming mainstream as a bridge to surgery (BTS). However, there are reports of worse prognoses due to stent placement, and the European Gastroenterology Society of Endoscopy guidelines do not recommend BTS. In our department, since 2011 the first choice of the treatment has been laparoscopic resection after decompression with a trans-anal or trans-nasal drainage tube. STo investigate the safety and short- and long-term results of laparoscopic resection after decompression with a drainage tube. Methods: Eighty-one cases of obstructive colorectal cancer that underwent surgery at our hospital from 2011 to 2016 were investigated with regards to the short- and long-term outcomes of treatment strategies for obstructive colorectal cancer. Results: The median age was 72 years old (39-94). The ratio of male to female was 46:29. The success rate of decompression was 86.7% (66 cases). Stages II, III and IV were involved in 25, 28 and 28 cases, respectively. The causes of the emergency operations were an inability to insert both the ileus tube and the stent (9.3%, 7 cases), and perforation (2.7%, 2 cases) when the trans-anal ileus tube was inserted. In the cases in which decompression was possible, the laparoscopic operation rate was 89.4% (56 cases) and the primary resection rate was 90.9% (59 cases). The median surgical time was 194 minutes (27-325), the median blood loss was 10 g (0-660 g),The median postoperative hospital stay was 14 days (5-147 days). The rate of anastomotic leak was 4.5%. There were no deaths within 30 and 90 days after surgery. The relapse free survival rate in Stage II and III were 72% and 67.9%, respectively. The median months of overall survival in Stage II, III and IV were 60.4, 56.3 and 18.7, respectively. Conclusions: A treatment strategy with laparoscopic resection followed by decompression with a drainage tube was performed feasibly and safely. At this time, the effects of a stent on oncological prognosis is unclear, and this strategy could be an effective treatment for obstructive colorectal cancer.

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Laparoscopic hepatic resection for metastatic liver tumor of colorectal cancer: comparative analysis of short- and long-term results

Surgical Endoscopy ◽

10.1007/s00464-013-3165-3 ◽

2013 ◽

Vol 28 (1) ◽

pp. 80-84 ◽

Cited By ~ 33

Author(s):

Shuichi Iwahashi ◽

Mitsuo Shimada ◽

Tohru Utsunomiya ◽

Satoru Imura ◽

Yuji Morine ◽

...

Keyword(s):

Colorectal Cancer ◽

Comparative Analysis ◽

Hepatic Resection ◽

Liver Tumor ◽

Metastatic Liver Tumor ◽

Long Term Results ◽

Laparoscopic Hepatic Resection ◽

Short And Long Term ◽

Metastatic Liver

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A Meta-Analysis of the Short- and Long-Term Results of Randomized Controlled Trials That Compared Laparoscopy-Assisted and Conventional Open Surgery for Colorectal Cancer

Journal of Cancer ◽

10.7150/jca.2.425 ◽

2011 ◽

Vol 2 ◽

pp. 425-434 ◽

Cited By ~ 30

Author(s):

Hiroshi Ohtani ◽

Yutaka Tamamori ◽

Yuichi Arimoto ◽

Yukio Nishiguchi ◽

Kiyoshi Maeda ◽

...

Keyword(s):

Colorectal Cancer ◽

Randomized Controlled Trials ◽

Open Surgery ◽

Meta Analysis ◽

Long Term Results ◽

Controlled Trials ◽

Randomized Controlled ◽

Short And Long Term ◽

Conventional Open Surgery

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ANALYSIS OF SHORT AND LONG-TERM RESULTS OF RECONSTRUCTIVE- RESTORATIVE PHASE AFTER THE OPERATIONS LIKE HARTMANN

Koloproktologia ◽

10.33878/2073-7556-2016-0-1-22-25 ◽

2016 ◽

pp. 22-25 ◽

Cited By ~ 1

Author(s):

I. G. Gataullin ◽

M. M. Khalikov

Keyword(s):

Colorectal Cancer ◽

Reconstructive Surgery ◽

Long Term Results ◽

Time Interval ◽

Hartmann Procedure ◽

Primary Surgery ◽

Optimal Period ◽

Short And Long Term ◽

Colorectal Cancer Patients

AIM. To improve short and long-term results of reconstructive surgery in patients with complicated colorectal cancer. PATIENTS AND METHODS. Results of 63 patients who had Hartmann procedure for complicated colorectal cancer and thereafter undergone reconstructive surgery were analized. RESULTS. Restorative surgerys was performed at different time interval after the primary surgery. Sphincterometry was done in all patients with the aim to assess the functional integrity of the anal sphincter. CONCLUSION. Suggested optimal period for reconstructive surgery is 1-3 months after the primary surgery.

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Perioperative use of anti-EGFR antibodies in resectable and potentially resectable liver metastases

Malignant tumours ◽

10.18027/2224-5057-2019-9-4-70-74 ◽

2020 ◽

Vol 9 (4) ◽

pp. 70-74

Author(s):

N. V. Zhukov

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Preoperative Chemotherapy ◽

Long Term Results ◽

R0 Resection ◽

Routine Practice ◽

Number Of Patients ◽

Long Term Treatment ◽

The Impact

The radical resection of all visible disease manifestations can significantly improve the prognosis of patients with metastatic colorectal cancer, however, complete metastasectomy is initially possible only in a small proportion of patients, with many of them subsequently developing relapse. Aiming to increase the number of patients subject to radical intervention and to reduce the recurrence risk, preoperative chemotherapy (with or without subsequent adjuvant treatment) is widely used in routine practice. In the hope of increasing immediate effectiveness (increasing the proportion of patients subject to R0 resection) and the long-term results of treatment, preoperative chemotherapy is often accompanied with biological agents (anti-EGFR and anti-VEGF monoclonal antibodies) continued after surgery in some cases. However, despite the evidence of increased resectability, the impact of this approach on long-term treatment outcomes has not yet been determined. The analysis of recent studies in this area doubts the safety of perioperative use of anti-EGFR antibodies in patients with potentially curable metastatic colorectal cancer.

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