Vaginal Practices and Associations with Barrier Methods and Gel Use Among Sub-Saharan African Women Enrolled in an HIV Prevention Trial

In sub-Saharan Africa, HIV incidence andprevalence remain disproportionately high among women.Vaginal rings (VRs) have been formulated for the deliveryof antiretroviral-based microbicides, and their favorablesafety and tolerability profiles reported in clinical studies.Although the concept of drug release through a VR hasexisted since 1970, and VRs have been marketed since1992 for contraceptive or hormone replacement purposes,VR use as a microbicide delivery system is a novelapplication. This is the first study to evaluate VR adherenceamong African women in the context of its potential use asan HIV prevention method, to examine predictors ofadherence, and to describe clinical or contextual reasonsfor VR removals or nonadherence. This was a randomizedtrial of the safety and acceptability of a placebo VR wornfor 12 weeks in 170 HIV-negative, African women aged18–35 in four clinic sites in South Africa and Tanzania.The findings suggest that adherence to VR use in thecontext of HIV prevention trials in these communitiesshould be high, thereby enabling more accurate assessmentof an active microbicide safety and efficacy.Keywords Vaginal ring ? Adherence ? Sub-SaharanAfrica ? Female-controlled HIV prevention methods ?Microbicide delivery

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NewsCAP: A game changer in HIV prevention in sub-Saharan African women.

AJN American Journal of Nursing ◽

10.1097/01.naj.0000734068.37456.24 ◽

2021 ◽

Vol 121 (2) ◽

pp. 15-15

Keyword(s):

Hiv Prevention ◽

African Women ◽

Sub Saharan ◽

Game Changer

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Three integrated elements of empowerment: HIV prevention with sub-Saharan African adolescent females involved in transactional sex.

Clinical Practice in Pediatric Psychology ◽

10.1037/cpp0000251 ◽

2018 ◽

Vol 6 (4) ◽

pp. 355-363 ◽

Cited By ~ 2

Author(s):

Sarah W. Feldstein Ewing ◽

Angela D. Bryan ◽

Tutu Alicante ◽

P. Todd Korthuis ◽

Karen A. Hudson ◽

...

Keyword(s):

Hiv Prevention ◽

Adolescent Females ◽

Transactional Sex ◽

Sub Saharan

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Intersectional stigma and its impact on HIV prevention and care among MSM and WSW in sub-Saharan African countries: a protocol for a scoping review

BMJ Open ◽

10.1136/bmjopen-2020-047280 ◽

2021 ◽

Vol 11 (8) ◽

pp. e047280

Author(s):

Gamji M’Rabiu Abubakari ◽

Debbie Dada ◽

Jemal Nur ◽

DeAnne Turner ◽

Amma Otchere ◽

...

Keyword(s):

Hiv Prevention ◽

Data Extraction ◽

Grey Literature ◽

Secondary Data ◽

Well Being ◽

Sub Saharan Africa ◽

African Countries ◽

Scoping Reviews ◽

Sub Saharan ◽

Meta Analyses

IntroductionResearch has established that various forms of stigma (HIV stigma, gender non-conforming stigma and same-gender sex stigma) exist across Sub-Saharan Africa and have consequences for the utilisation of HIV prevention and care services. Stigmas are typically investigated in HIV literature individually or through investigating individual populations and the various stigmas they may face. The concept of intersectionality highlights the interconnected nature of social categorisations and their ability to create interdependent systems of discrimination based on gender, race, sexuality and so on. Drawing from perspectives on intersectionality, intersectional stigma denotes the convergence of multiple marginalised identities within an individual or a group, the experiences of stigma associated with these identities as well as the synergistic impact of these experiences on health and well-being. With respect to HIV, public health scholars can examine the impacts of intersectional stigmas on HIV prevention and care utilisation.Methods and analysisReviewers will search systematically through MEDLINE, Global Health, Embase, Scopus, Web of Science Core Collection and Africa Index Medicus and citations for quantitative studies, qualitative studies and grey literature that include data on stigma and HIV among men who have sex with men and women who have sex with women in Sub-Saharan Africa. Eligible studies will include primary or secondary data on stigma related to HIV risk factors experienced by this population. Studies will be written in French or English and be published between January 1991 and November 2020. All screening and data extraction will be performed in duplicate, and if discrepancies arise, they will be settled by GM’RA, LEN, DD or AO. Findings from this study will be reported according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews.Ethics and disseminationEthics approval is not required as there will be no human participants and no protected data will be used in this study. We will disseminate findings through peer-reviewed manuscripts, conferences and webinars.

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