Specific Features of Intracellular Signal Transduction in the Regulation of Functions of Neural Stem Cells and Committed Neuronal Progenitors

2021 ◽  
Vol 170 (4) ◽  
pp. 522-527
Author(s):  
G. N. Zyuz’kov ◽  
L. A. Miroshnichenko ◽  
T. Yu. Polyakova ◽  
V. V. Zhdanov ◽  
E. V. Simanina ◽  
...  
2004 ◽  
Vol 52 (S 1) ◽  
Author(s):  
N Kayhan ◽  
K Sonnenberg ◽  
A Bonz ◽  
G Reinerth ◽  
S Hagl ◽  
...  

2020 ◽  
Vol 168 (3) ◽  
pp. 356-360 ◽  
Author(s):  
G. N. Zyuz’kov ◽  
L. A. Miroshnichenko ◽  
T. Yu. Polyakova ◽  
L. A. Stavrova ◽  
E. V. Simanina ◽  
...  

Acta Naturae ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 65-76
Author(s):  
Oleg A. Kuchur ◽  
Daria O. Kuzmina ◽  
Marina S. Dukhinova ◽  
Alexandr A. Shtil

Survival mechanisms are activated in tumor cells in response to therapeutic ionizing radiation. This reduces a treatments effectiveness. The p53, p63, and p73 proteins belonging to the family of proteins that regulate the numerous pathways of intracellular signal transduction play a key role in the development of radioresistance. This review analyzes the p53-dependent and p53-independent mechanisms involved in overcoming the resistance of tumor cells to radiation exposure.


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