scholarly journals Preface to the special issue “Strategic applications of real-time risk mitigation strategies and tools: case studies and lessons learned in REAKT”

2016 ◽  
Vol 14 (9) ◽  
pp. 2437-2439 ◽  
Author(s):  
Carlo Cauzzi ◽  
Paolo Gasparini ◽  
Stefan Wiemer ◽  
Jochen Zschau
Keyword(s):  
Real Time ◽  
Case Studies ◽  
Risk Mitigation ◽  
Lessons Learned ◽  
Mitigation Strategies ◽  
Special Issue ◽  
Risk Mitigation Strategies

scholarly journals Planetary extravehicular activity (EVA) risk mitigation strategies for long-duration space missions

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Blaze Belobrajdic ◽  
Kate Melone ◽  
Ana Diaz-Artiles
Keyword(s):  
Decompression Sickness ◽  
Risk Mitigation ◽  
Space Missions ◽  
Lessons Learned ◽  
Mitigation Strategies ◽  
Planetary Surface ◽  
Extravehicular Activity ◽  
Long Duration ◽  
Surface Exploration ◽  
Risk Mitigation Strategies

AbstractExtravehicular activity (EVA) is one of the most dangerous activities of human space exploration. To ensure astronaut safety and mission success, it is imperative to identify and mitigate the inherent risks and challenges associated with EVAs. As we continue to explore beyond low earth orbit and embark on missions back to the Moon and onward to Mars, it becomes critical to reassess EVA risks in the context of a planetary surface, rather than in microgravity. This review addresses the primary risks associated with EVAs and identifies strategies that could be implemented to mitigate those risks during planetary surface exploration. Recent findings within the context of spacesuit design, Concept of Operations (CONOPS), and lessons learned from analog research sites are summarized, and how their application could pave the way for future long-duration space missions is discussed. In this context, we divided EVA risk mitigation strategies into two main categories: (1) spacesuit design and (2) CONOPS. Spacesuit design considerations include hypercapnia prevention, thermal regulation and humidity control, nutrition, hydration, waste management, health and fitness, decompression sickness, radiation shielding, and dust mitigation. Operational strategies discussed include astronaut fatigue and psychological stressors, communication delays, and the use of augmented reality/virtual reality technologies. Although there have been significant advances in EVA performance, further research and development are still warranted to enable safer and more efficient surface exploration activities in the upcoming future.

scholarly journals Canadian perspective on managing multiple myeloma during the COVID-19 pandemic: lessons learned and future considerations

2020 ◽  
Vol 27 (5) ◽  
Author(s):  
R. Foley ◽  
R. Kaedbey ◽  
K. Song ◽  
C.P. Venner ◽  
D. White ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Risk Mitigation ◽  
Lessons Learned ◽  
Mitigation Strategies ◽  
The Novel ◽  
Vulnerable Patients ◽  
Increased Risk ◽  
Canadian Perspective ◽  
Risk Mitigation Strategies ◽  
Second Wave

  The coronavirus disease 2019 (covid-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 has necessitated changes to the way patients with chronic diseases are managed. Given that patients with multiple myeloma are at increased risk of covid-19 infection and related complications, national bodies and experts around the globe have made recommendations for risk mitigation strategies for those vulnerable patients. Understandably, because of the novelty of the virus, many of the proposed risk mitigation strategies have thus far been reactionary and cannot be supported by strong evidence. In this editorial, we highlight some of the risk mitigation strategies implemented at our institutions across Canada during the first wave of covid-19, and we discuss the considerations that should be made when managing patients during the second wave and beyond.

scholarly journals Impact and effectiveness of risk mitigation strategies on the insurability of nanomaterial production: evidences from industrial case studies

2015 ◽  
Vol 7 (6) ◽  
pp. 839-855 ◽  
Author(s):  
Enrico Bergamaschi ◽  
Finbarr Murphy ◽  
Craig A. Poland ◽  
Martin Mullins ◽  
Anna L. Costa ◽  
...  
Keyword(s):  
Case Studies ◽  
Risk Mitigation ◽  
Mitigation Strategies ◽  
Risk Mitigation Strategies

scholarly journals Use of failure modes and effects analysis to mitigate potential risks prior to implementation of an intravenous compounding technology

2021 ◽  
Author(s):  
Agnes Ann Feemster ◽  
Melissa Augustino ◽  
Rosemary Duncan ◽  
Anand Khandoobhai ◽  
Meghan Rowcliffe
Keyword(s):  
Medication Safety ◽  
Failure Modes ◽  
Risk Mitigation ◽  
New Technology ◽  
Hazard Index ◽  
Mitigation Strategies ◽  
Investigational Drug ◽  
Workflow Optimization ◽  
Proactive Approach ◽  
Risk Mitigation Strategies

Abstract Disclaimer In an effort to expedite the publication of articles related to the COVID-19 pandemic, AJHP is posting these manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. Purpose The purpose of this study was to identify potential failure points in a new chemotherapy preparation technology and to implement changes that prevent or minimize the consequences of those failures before they occur using the failure modes and effects analysis (FMEA) approach. Methods An FMEA was conducted by a team of medication safety pharmacists, oncology pharmacists and technicians, leadership from informatics, investigational drug, and medication safety services, and representatives from the technology vendor. Failure modes were scored using both Risk Priority Number (RPN) and Risk Hazard Index (RHI) scores. Results The chemotherapy preparation workflow was defined in a 41-step process with 16 failure modes. The RPN and RHI scores were identical for each failure mode because all failure modes were considered detectable. Five failure modes, all attributable to user error, were deemed to pose the highest risk. Mitigation strategies and system changes were identified for 2 failure modes, with subsequent system modifications resulting in reduced risk. Conclusion The FMEA was a useful tool for risk mitigation and workflow optimization prior to implementation of an intravenous compounding technology. The process of conducting this study served as a collaborative and proactive approach to reducing the potential for medication errors upon adoption of new technology into the chemotherapy preparation process.

A Low-Fidelity Stochastic Model of Viral Spread in Aircraft to Assess Risk Mitigation Strategies

2021 ◽  
Author(s):  
Leigh McCue
Keyword(s):  
Large Scale ◽  
Risk Mitigation ◽  
Mitigation Strategies ◽  
Traffic Network ◽  
Computationally Efficient ◽  
Passenger Compartment ◽  
Stochastic Effects ◽  
Viral Spread ◽  
Risk Mitigation Strategies ◽  
Baseline Health

Abstract The purpose of this work is to develop a computationally efficient model of viral spread that can be utilized to better understand influences of stochastic factors on a large-scale system - such as the air traffic network. A particle-based model of passengers and seats aboard a single-cabin 737-800 is developed for use as a demonstration of concept on tracking the propagation of a virus through the aircraft's passenger compartment over multiple flights. The model is sufficiently computationally efficient so as to be viable for Monte Carlo simulation to capture various stochastic effects, such as number of passengers, number of initially sick passengers, seating locations of passengers, and baseline health of each passenger. The computational tool is then exercised in demonstration for assessing risk mitigation of intervention strategies, such as passenger-driven cleaning of seating environments and elimination of middle seating.

scholarly journals Management of Cardiac Implantable Electrical Devices in Patients Undergoing Radiofrequency Ablation for Spine Pain: Physician Survey and Review of Guidelines

2020 ◽  
Vol 4;23 (7;4) ◽  
pp. E335-E342
Author(s):  
Jason Friedrich
Keyword(s):  
Decision Making ◽  
Chronic Pain ◽  
Radiofrequency Ablation ◽  
Joint Pain ◽  
Risk Mitigation ◽  
Narrative Review ◽  
Mitigation Strategies ◽  
Web Based ◽  
Electrical Devices ◽  
Risk Mitigation Strategies

Background: More patients with cardiac implantable electrical devices (CIEDs) are presenting to spine and pain practices for radiofrequency ablation (RFA) procedures for chronic pain. Although the potential for electromagnetic interference (EMI) affecting CIED function is known with RFA procedures, available guidelines do not specifically address CIED management for percutaneous RFA for zygapophyseal (z-joint) joint pain, and thus physician practice may vary. Objectives: To better understand current practices of physicians who perform RFA for chronic z-joint pain with respect to management of CIEDs. Perioperative CIED management guidelines are also reviewed to specifically address risk mitigation strategies for potential EMI created by ambulatory percutaneous spine RFA procedures. Study Design: Web-based provider survey and narrative review. Setting: Multispecialty pain clinic, academic medical center. Methods: A web-based survey was created using Research Electronic Data Capture (REDCap). A survey link was provided via e-mail to active members of the Spine Intervention Society (SIS), American Society of Regional Anesthesia and Pain Medicine, as well as distributed freely to community Pain Physicians and any receptive academic departments of PM&R or Anesthesiology. The narrative review summarizes pertinent case series, review articles, a SIS recommendation statement, and multi-specialty peri-operative guidelines as they relate specifically to spine RFA procedures. Results: A total of 197 clinicians participated in the survey from diverse clinical backgrounds, including anesthesiology, physical medicine and rehabilitation, radiology, neurosurgery, and neurology, with 81% reporting fellowship training. Survey responses indicate wide variability in provider management of CIEDs before, during, and after RFA for z-joint pain. Respondents indicated they would like more specific guidelines to aid in management and decision-making around CIEDs and spine RFA procedures. Literature review yielded several practice guidelines related to perioperative management of CIEDs, but no specific guideline for percutaneous spine RFA procedures. However, combining the risk mitigation strategies provided in these guidelines, with interventional pain physician clinical experience allows for reasonable management recommendations to aid in decision-making. Limitations: Although this manuscript can serve as a review of CIEDs and aid in management decisions in patients with CIEDs, it is not a clinical practice guideline. Conclusions: Practice patterns vary regarding CIED management in ambulatory spine RFA procedures. CIED presence is not a contraindication for spine RFA but does increase the complexity of a spine RFA procedure and necessitates some added precautions. Key words: Radiofrequency ablation, neurotomy, cardiac implantable electrical device, zygapophyseal joint, spondylosis, neck pain, low back pain, chronic pain

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