Comparison of Monofractal, Multifractal and gray level Co-occurrence matrix algorithms in analysis of Breast tumor microscopic images for prognosis of distant metastasis risk

2016 ◽  
Vol 18 (5) ◽  
Author(s):  
Nemanja Rajković ◽  
Daniela Kolarević ◽  
Ksenija Kanjer ◽  
Nebojša T. Milošević ◽  
Dragica Nikolić-Vukosavljević ◽  
...  
2015 ◽  
Vol 21 (3) ◽  
pp. 646-654 ◽  
Author(s):  
Tijana Vujasinovic ◽  
Jelena Pribic ◽  
Ksenija Kanjer ◽  
Nebojsa T. Milosevic ◽  
Zorica Tomasevic ◽  
...  

AbstractOwing to exceptional heterogeneity in the outcome of invasive breast cancer it is essential to develop highly accurate prognostic tools for effective therapeutic management. Based on this pressing need, we aimed to improve breast cancer prognosis by exploring the prognostic value of tumor histology image analysis. Patient group (n=78) selection was based on invasive breast cancer diagnosis without systemic treatment with a median follow-up of 147 months. Gray-level co-occurrence matrix texture analysis was performed retrospectively on primary tumor tissue section digital images stained either nonspecifically with hematoxylin and eosin or specifically with a pan-cytokeratin antibody cocktail for epithelial malignant cells. Univariate analysis revealed stronger association with metastasis risk by texture analysis when compared with clinicopathological parameters. The combination of individual clinicopathological and texture variables into composite scores resulted in further powerful enhancement of prognostic performance, with an accuracy of up to 90%, discrimination efficiency by the area under the curve [95% confidence interval (CI)] of 0.94 (0.87–0.99) and hazard ratio (95% CI) of 20.1 (7.5–109.4). Internal validation was successfully performed by bootstrap and split-sample cross-validation, suggesting that the models are generalizable. Whereas further validation is needed on an external set of patients, this preliminary study indicates the potential use of primary breast tumor histology texture as a highly accurate, simple, and cost-effective prognostic indicator of distant metastasis risk.


Data visualization is the technique for analyzing the data from the collected dataset. Different plots can be drawn for the data visualization. Microscopic images of the liver are being collected as a dataset from the authorized laboratory and the Joint plot, Violin plot and distribution plot are applied on them for the analysis which helps to extract the specific features and for the classification. Joint plot uses the scatter plot and Histogram technique in order to visualize the data. Violin plot technique is used for plotting the numeric data which helps in gray level co-occurrence matrix. Distribution graph is plotted to check the distribution of tones captured in the image so that we can differentiate based on the tones. All three graphs plotted extract the different features which help in efficient analysis.


2012 ◽  
Vol 31 (6) ◽  
pp. 1628-1630
Author(s):  
Jia-jia OU ◽  
Bi-ye CAI ◽  
Bing XIONG ◽  
Feng LI

2019 ◽  
Vol 13 (2) ◽  
pp. 136-141 ◽  
Author(s):  
Abhisek Sethy ◽  
Prashanta Kumar Patra ◽  
Deepak Ranjan Nayak

Background: In the past decades, handwritten character recognition has received considerable attention from researchers across the globe because of its wide range of applications in daily life. From the literature, it has been observed that there is limited study on various handwritten Indian scripts and Odia is one of them. We revised some of the patents relating to handwritten character recognition. Methods: This paper deals with the development of an automatic recognition system for offline handwritten Odia character recognition. In this case, prior to feature extraction from images, preprocessing has been done on the character images. For feature extraction, first the gray level co-occurrence matrix (GLCM) is computed from all the sub-bands of two-dimensional discrete wavelet transform (2D DWT) and thereafter, feature descriptors such as energy, entropy, correlation, homogeneity, and contrast are calculated from GLCMs which are termed as the primary feature vector. In order to further reduce the feature space and generate more relevant features, principal component analysis (PCA) has been employed. Because of the several salient features of random forest (RF) and K- nearest neighbor (K-NN), they have become a significant choice in pattern classification tasks and therefore, both RF and K-NN are separately applied in this study for segregation of character images. Results: All the experiments were performed on a system having specification as windows 8, 64-bit operating system, and Intel (R) i7 – 4770 CPU @ 3.40 GHz. Simulations were conducted through Matlab2014a on a standard database named as NIT Rourkela Odia Database. Conclusion: The proposed system has been validated on a standard database. The simulation results based on 10-fold cross-validation scenario demonstrate that the proposed system earns better accuracy than the existing methods while requiring least number of features. The recognition rate using RF and K-NN classifier is found to be 94.6% and 96.4% respectively.


ICT Express ◽  
2021 ◽  
Author(s):  
Fitri Utaminingrum ◽  
Syam Julio A. Sarosa ◽  
Corina Karim ◽  
Femiana Gapsari ◽  
Randy Cahya Wihandika

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