scholarly journals Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors

2017 ◽  
Vol 168 (2) ◽  
pp. 467-479 ◽  
Author(s):  
Sarah J. O. Nomura ◽  
Yi-Ting Hwang ◽  
Scarlett Lin Gomez ◽  
Teresa T. Fung ◽  
Shu-Lan Yeh ◽  
...  
2018 ◽  
Vol 168 (2) ◽  
pp. 481-482 ◽  
Author(s):  
Sarah J. O. Nomura ◽  
Yi-Ting Hwang ◽  
Scarlett Lin Gomez ◽  
Teresa T. Fung ◽  
Shu-Lan Yeh ◽  
...  

2013 ◽  
Vol 22 (10) ◽  
pp. 2709-2720 ◽  
Author(s):  
Judy Huei-yu Wang ◽  
Inez F. Adams ◽  
Reginald Tucker-Seeley ◽  
Scarlett Lin Gomez ◽  
Laura Allen ◽  
...  

2012 ◽  
Vol 124 (3) ◽  
pp. 383-388 ◽  
Author(s):  
Judy Huei-yu Wang ◽  
Inez Adams ◽  
Ellen Huang ◽  
Kimlin Ashing-Giwa ◽  
Scarlett Lin Gomez ◽  
...  

2008 ◽  
Vol 108 (8) ◽  
pp. 1323-1329 ◽  
Author(s):  
María A. Hernández-Valero ◽  
Cynthia A. Thomson ◽  
Mike Hernández ◽  
Taylor Tran ◽  
Michelle A. Detry ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Christina M. Dieli-Conwright ◽  
Nathalie Sami ◽  
Mary K. Norris ◽  
Junxiang Wan ◽  
Hiroshi Kumagai ◽  
...  

AbstractMOTS-c is a mitochondrial derived peptide with exercise mimetic activity that elicits beneficial effects on metabolism and exercise capacity. Furthermore, MOTS-c effects in humans are affected by race, potentially via ethnic-specific mtDNA variations. Women treated for breast cancer are at an increased risk for cardiovascular disease, diabetes and obesity, due to side effects of cancer-treatments. We conducted a secondary analysis of the effects of a 16-week aerobic and resistance exercise intervention on MOTS-c in Hispanic and Non-Hispanic White breast cancer survivors (BCS). BCS (Stage I–III) were randomized to exercise or standard care. The intervention promoted aerobic and resistance exercise for 16 weeks. MOTS-c was analyzed in fasting plasma using an in-house ELISA. Within and between group differences were assessed by paired t-test and repeated measures ANOVA. Pearson’s correlation was computed to assess the association between MOTS-c and metabolic biomarkers at baseline and post-exercise. Twenty-five Hispanic-BCS and 24 non-Hispanic White BCS were included. Hispanic BCS were younger, of greater adiposity, had higher stage cancers, and had worse metabolic profiles at baseline compared to non-Hispanic White BCS (p < 0.001). Post-exercise, MOTS-c levels significantly increased when compared to baseline and the usual care group among non-Hispanic White BCS (p < 0.01) but not among Hispanic breast cancer survivors (p > 0.01). Post-exercise levels of MOTS-c among non-Hispanic White BCS were significantly associated with reductions in fat mass, body weight, HOMA-IR, CRP, and an increase in lean mass (p < 0.01). A 16-week aerobic and resistance intervention increased MOTS-c levels among non-Hispanic White BCS. Trial registration: This trial is registered on ClinicalTrials.gov: NCT01140282 as of June 9, 2010. https://clinicaltrials.gov/ct2/show/NCT01140282.


Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3394
Author(s):  
Sarah A. Purcell ◽  
Ryan J. Marker ◽  
Marc-Andre Cornier ◽  
Edward L. Melanson

Many breast cancer survivors (BCS) gain fat mass and lose fat-free mass during treatment (chemotherapy, radiation, surgery) and estrogen suppression therapy, which increases the risk of developing comorbidities. Whether these body composition alterations are a result of changes in dietary intake, energy expenditure, or both is unclear. Thus, we reviewed studies that have measured components of energy balance in BCS who have completed treatment. Longitudinal studies suggest that BCS reduce self-reported energy intake and increase fruit and vegetable consumption. Although some evidence suggests that resting metabolic rate is higher in BCS than in age-matched controls, no study has measured total daily energy expenditure (TDEE) in this population. Whether physical activity levels are altered in BCS is unclear, but evidence suggests that light-intensity physical activity is lower in BCS compared to age-matched controls. We also discuss the mechanisms through which estrogen suppression may impact energy balance and develop a theoretical framework of dietary intake and TDEE interactions in BCS. Preclinical and human experimental studies indicate that estrogen suppression likely elicits increased energy intake and decreased TDEE, although this has not been systematically investigated in BCS specifically. Estrogen suppression may modulate energy balance via alterations in appetite, fat-free mass, resting metabolic rate, and physical activity. There are several potential areas for future mechanistic energetic research in BCS (e.g., characterizing predictors of intervention response, appetite, dynamic changes in energy balance, and differences in cancer sub-types) that would ultimately support the development of more targeted and personalized behavioral interventions.


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