Comparison of global strain values of myocardium in beta-thalassemia major patients with iron load using specific feature tracking in cardiac magnetic resonance imaging

2020 ◽  
Vol 36 (7) ◽  
pp. 1343-1349
Author(s):  
Nahid Rezaeian ◽  
Masoumeh Ahmadi Mohtasham ◽  
Azad Jameel Khaleel ◽  
Neda Parnianfard ◽  
Kianoosh Kasani ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Cardiac Magnetic Resonance Imaging ◽  
Feature Tracking ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Resonance Imaging ◽  
Iron Load ◽  
Global Strain

Atrial Strain by Feature-Tracking Cardiac Magnetic Resonance Imaging in Takotsubo Cardiomyopathy. Features, Feasibility, and Reproducibility

2021 ◽  
pp. 084653712110424
Author(s):  
Riccardo Cau ◽  
Pierpaolo Bassareo ◽  
Gloria Caredda ◽  
Jasjit S. Suri ◽  
Antonio Esposito ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Strain Rate ◽  
Cardiac Magnetic Resonance Imaging ◽  
Takotsubo Cardiomyopathy ◽  
Feature Tracking ◽  
Resonance Imaging ◽  
Strain And Strain Rate ◽  
Atrial Strain

Objectives: The purpose of this study was to investigate whether there may be a bi-atrial dysfunction in Takotsubo syndrome (TS) during the transient course of the disease, using cardiac magnetic resonance imaging feature tracking (CMR-FT) in analyzing bi-atrial strain. Method: Eighteen TS patients and 13 healthy controls were studied. Reservoir, conduit, and booster bi-atrial functions were analyzed by CMR-FT. The correlation between LA and RA strain parameters was assessed. Intra- and inter-observer reproducibility was evaluated for all strain and strain rate (SR) parameters using intraclass correlation coefficients (ICCs) and Bland-Altman analysis. Results: Atrial strain were feasible in all patients and controls. Takotsubo patients showed an impaired LA Reservoir strain (∊s), LA Reservoir strain rate (SRs), LA and RA Conduit strain(∊e), LA and RA conduit strain rate (SRe) in comparison with controls (P < 0.001 for all of them), while no differences were found as to LA and RA booster deformation parameters (∊a and SRa). Analysis of correlation showed that LA ∊s, SRs, ∊e, and SRe were positively correlated with corresponding RA strain measurements (P < 0.001, r = 0.61 and P = 0,03, r = 0,54, respectively). Reproducibility was good to excellent for all atrial strain and strain rate parameters (ICCs ranging from 0,50 to 0,96). Conclusion: Atrial strain analysis using CMR-FT may be a useful tool to reveal new pathophysiological insights in Takotsubo cardiomyopathy. Additional studies, with a larger number of patients, are needed to confirm the possible role of these advanced CMR tools in characterizing TS patients.

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