Nanomedicine as an emerging platform for metastatic lung cancer therapy

2015 ◽  
Vol 34 (2) ◽  
pp. 291-301 ◽  
Author(s):  
Dalit Landesman-Milo ◽  
Srinivas Ramishetti ◽  
Dan Peer
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Metastatic Lung Cancer ◽  
Metastatic Lung ◽  
Lung Cancer Therapy

Pulmonary delivery by exploiting doxorubicin and cisplatin co-loaded nanoparticles for metastatic lung cancer therapy

2019 ◽  
Vol 295 ◽  
pp. 153-163 ◽  
Author(s):  
Caina Xu ◽  
Yanbing Wang ◽  
Zhaopei Guo ◽  
Jie Chen ◽  
Lin Lin ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Pulmonary Delivery ◽  
Metastatic Lung Cancer ◽  
Metastatic Lung ◽  
Lung Cancer Therapy

scholarly journals Chimeric antigen receptor T cell targeting EGFRvIII for metastatic lung cancer therapy

2019 ◽  
Vol 13 (1) ◽  
pp. 57-68 ◽  
Author(s):  
Zhao Zhang ◽  
Jun Jiang ◽  
Xiaodong Wu ◽  
Mengyao Zhang ◽  
Dan Luo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
T Cell ◽  
Cancer Therapy ◽  
Chimeric Antigen Receptor ◽  
Antigen Receptor ◽  
Metastatic Lung Cancer ◽  
Cell Targeting ◽  
Metastatic Lung ◽  
Lung Cancer Therapy

Sleep Disturbances in Metastatic Lung Cancer

2019 ◽  
Author(s):  
M. Kaous ◽  
D.D. Balachandran ◽  
G. Pacheco ◽  
S.A. Mahoney ◽  
J.N.T. Po ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Sleep Disturbances ◽  
Metastatic Lung Cancer ◽  
Metastatic Lung

scholarly journals Patients with Metastatic Lung Cancer and Oncologists’ Views on Achievement of Treatment Goals and Making the Right Treatment Decision: A Prospective Multicenter Study

2021 ◽  
pp. 0272989X2199895
Author(s):  
Adinda Mieras ◽  
Annemarie Becker-Commissaris ◽  
Hanna T. Klop ◽  
H. Roeline W. Pasman ◽  
Denise de Jong ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Multicenter Study ◽  
Systemic Treatment ◽  
Treatment Decision ◽  
Treatment Goals ◽  
Metastatic Lung Cancer ◽  
Prospective Multicenter Study ◽  
Cancer Data ◽  
Metastatic Lung ◽  
The Right

Background Previous studies have investigated patients’ treatment goals before starting a treatment for metastatic lung cancer. Data on the evaluation of treatment goals are lacking. Aim To determine if patients with metastatic lung cancer and their oncologists perceive the treatment goals they defined at the start of systemic treatment as achieved after treatment and if in hindsight they believe it was the right decision to start systemic therapy. Design and Participants A prospective multicenter study in 6 hospitals across the Netherlands between 2016 and 2018. Following systemic treatment, 146 patients with metastatic lung cancer and 23 oncologists completed a questionnaire on the achievement of their treatment goals and whether they made the right treatment decision. Additional interviews with 15 patients and 5 oncologists were conducted. Results According to patients and oncologists, treatment goals were achieved in 30% and 37% for ‘quality of life,’ 49% and 41% for ‘life prolongation,’ 26% and 44% for ‘decrease in tumor size,’ and 44% for ‘cure’, respectively. Most patients and oncologists, in hindsight, felt they had made the right decision to start treatment and also if they had not achieved their goals (72% and 93%). This was related to the feeling that they had to do ‘something.’ Conclusions Before deciding on treatment, the treatment options, including their benefits and side effects, and the goals patients have should be discussed. It is key that these discussions include not only systemic treatment but also palliative care as effective options for doing ‘something.’

Enhancement of gold-nanocluster-mediated chemotherapeutic efficiency of cisplatin in lung cancer

2021 ◽  
Author(s):  
Mei Jiang ◽  
Yuchen Lin ◽  
Xiaocui Fang ◽  
Mingpeng Liu ◽  
Lilusi Ma ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Delivery System ◽  
Gold Nanoclusters ◽  
Cationic Peptide ◽  
Gold Nanocluster ◽  
Lung Cancer Therapy ◽  
Anti Tumor Activity

A novel delivery system for cisplatin based on electrostatics-mediated assemblies of gold nanoclusters and PEGylated cationic peptide was constructed. The constructed cisplatin@GC-pKs showed much enhanced anti-tumor activity for lung cancer therapy.

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