Controlled release and long-term antibacterial activity of chlorhexidine digluconate through the nanoporous network of microfibrillated cellulose

Cellulose ◽  
2014 ◽  
Vol 21 (6) ◽  
pp. 4429-4442 ◽  
Author(s):  
Nathalie Lavoine ◽  
Isabelle Desloges ◽  
Cécile Sillard ◽  
Julien Bras
Keyword(s):  
Antibacterial Activity ◽  
Controlled Release ◽  
Microfibrillated Cellulose ◽  
Chlorhexidine Digluconate

Controlled release of chlorhexidine digluconate using β-cyclodextrin and microfibrillated cellulose

2014 ◽  
Vol 121 ◽  
pp. 196-205 ◽  
Author(s):  
Nathalie Lavoine ◽  
Nicolas Tabary ◽  
Isabelle Desloges ◽  
Bernard Martel ◽  
Julien Bras
Keyword(s):  
Controlled Release ◽  
Microfibrillated Cellulose ◽  
Chlorhexidine Digluconate

Long-Term Efficacy of Diltiazem Controlled Release Versus Metoprolol in Patients with Stable Angina Pectoris

1991 ◽  
Vol 18 ◽  
pp. S55-S60
Author(s):  
H. W. Vliegen ◽  
E. E. van der Wall ◽  
M. G. Niemeyer ◽  
N. J. Holwerda ◽  
P. J. L. M. Bernink ◽  
...  
Keyword(s):  
Controlled Release ◽  
Angina Pectoris ◽  
Stable Angina ◽  
Stable Angina Pectoris ◽  
Term Efficacy

Results of long-term treatment with controlled-release levodopa/carbidopa (Sinemet CR)

1990 ◽  
Vol 2 (3) ◽  
pp. 205-213 ◽  
Author(s):  
J. M. Cedarbaum ◽  
M. Silvestri ◽  
M. Clark ◽  
L. Toy ◽  
A. Harts ◽  
...  
Keyword(s):  
Controlled Release ◽  
Term Treatment ◽  
Long Term Treatment

In Situ Preparation of Ag-Deposited Mesoporous Silica Hollow Spheres with Long-Term Antibacterial Activity

2014 ◽  
Vol 8 (3) ◽  
pp. 230-234 ◽  
Author(s):  
Peng Xu ◽  
Yixi Chen ◽  
Rui Zhang ◽  
Jing Yang ◽  
Xiaoyong Cao ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Mesoporous Silica ◽  
Hollow Spheres

scholarly journals Iodine-Loaded Calcium Titanate for Bone Repair with Sustainable Antibacterial Activity Prepared by Solution and Heat Treatment

Nanomaterials ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2199
Author(s):  
Seiji Yamaguchi ◽  
Phuc Thi Minh Le ◽  
Seine A. Shintani ◽  
Hiroaki Takadama ◽  
Morihiro Ito ◽  
...  
Keyword(s):  
Heat Treatment ◽  
Antibacterial Activity ◽  
Bone Repair ◽  
Reduction Rate ◽  
Calcium Titanate ◽  
Apatite Formation ◽  
Oh Groups ◽  
Long Term Stability ◽  
Combined Solution

In the orthopedic and dental fields, simultaneously conferring titanium (Ti) and its alloy implants with antibacterial and bone-bonding capabilities is an outstanding challenge. In the present study, we developed a novel combined solution and heat treatment that controllably incorporates 0.7% to 10.5% of iodine into Ti and its alloys by ion exchange with calcium ions in a bioactive calcium titanate. The treated metals formed iodine-containing calcium-deficient calcium titanate with abundant Ti-OH groups on their surfaces. High-resolution XPS analysis revealed that the incorporated iodine ions were mainly positively charged. The surface treatment also induced a shift in the isoelectric point toward a higher pH, which indicated a prevalence of basic surface functionalities. The Ti loaded with 8.6% iodine slowly released 5.6 ppm of iodine over 90 days and exhibited strong antibacterial activity (reduction rate >99%) against methicillin-resistant Staphylococcus aureus (MRSA), S. aureus, Escherichia coli, and S. epidermidis. A long-term stability test of the antibacterial activity on MRSA showed that the treated Ti maintained a >99% reduction until 3 months, and then it gradually decreased after 6 months (to a 97.3% reduction). There was no cytotoxicity in MC3T3-E1 or L929 cells, whereas apatite formed on the treated metal in a simulated body fluid within 3 days. It is expected that the iodine-carrying Ti and its alloys will be particularly useful for orthopedic and dental implants since they reliably bond to bone and prevent infection owing to their apatite formation, cytocompatibility, and sustainable antibacterial activity.

Controlled Release of Antibiotic Cobex By Biosynthesize Copper Nanoparticles Using Osmium Sanctum and its Antibacterial Activity

2022 ◽  
pp. 131666
Author(s):  
Naiwei Li ◽  
Saruchi ◽  
Priyanka Thakur ◽  
Jyotsna Pandey ◽  
Vaneet Kumar
Keyword(s):  
Antibacterial Activity ◽  
Controlled Release ◽  
Copper Nanoparticles
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