Impact of Maternal Early Life Maltreatment and Maternal History of Depression on Child Psychopathology: Mediating Role of Maternal Sensitivity?

2018 ◽  
Vol 50 (2) ◽  
pp. 278-290 ◽  
Author(s):  
Katja Bödeker ◽  
Anna Fuchs ◽  
Daniel Führer ◽  
Dorothea Kluczniok ◽  
Katja Dittrich ◽  
...  
Keyword(s):  
Early Life ◽  
Child Psychopathology ◽  
Maternal Sensitivity ◽  
Maternal History ◽  
Mediating Role ◽  
History Of ◽  
History Of Depression

scholarly journals Effects of maternal history of depression and early life maltreatment on children's health-related quality of life

2018 ◽  
Vol 225 ◽  
pp. 280-288 ◽  
Author(s):  
Katja Dittrich ◽  
Anna Fuchs ◽  
Felix Bermpohl ◽  
Justus Meyer ◽  
Daniel Führer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Early Life ◽  
Children's Health ◽  
Health Related Quality ◽  
Maternal History ◽  
Related Quality ◽  
Health Related ◽  
History Of ◽  
History Of Depression

Maternal history of parentification and warm responsiveness: The mediating role of knowledge of infant development.

2015 ◽  
Vol 29 (6) ◽  
pp. 863-872 ◽  
Author(s):  
Amy K. Nuttall ◽  
Kristin Valentino ◽  
Lijuan Wang ◽  
Jennifer Burke Lefever ◽  
John G. Borkowski
Keyword(s):  
Infant Development ◽  
Maternal History ◽  
Mediating Role ◽  
History Of

scholarly journals Gene regulation contributes to explain the impact of early life socioeconomic disadvantage on adult inflammatory levels in two cohort studies

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Cristian Carmeli ◽  
Zoltán Kutalik ◽  
Pashupati P. Mishra ◽  
Eleonora Porcu ◽  
Cyrille Delpierre ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Gene Regulation ◽  
Cohort Studies ◽  
Early Life ◽  
Life Experiences ◽  
Socioeconomic Disadvantage ◽  
Mediating Role ◽  
The Impact ◽  
The Relationship

AbstractIndividuals experiencing socioeconomic disadvantage in childhood have a higher rate of inflammation-related diseases decades later. Little is known about the mechanisms linking early life experiences to the functioning of the immune system in adulthood. To address this, we explore the relationship across social-to-biological layers of early life social exposures on levels of adulthood inflammation and the mediating role of gene regulatory mechanisms, epigenetic and transcriptomic profiling from blood, in 2,329 individuals from two European cohort studies. Consistently across both studies, we find transcriptional activity explains a substantive proportion (78% and 26%) of the estimated effect of early life disadvantaged social exposures on levels of adulthood inflammation. Furthermore, we show that mechanisms other than cis DNA methylation may regulate those transcriptional fingerprints. These results further our understanding of social-to-biological transitions by pinpointing the role of gene regulation that cannot fully be explained by differential cis DNA methylation.

scholarly journals Exposure to socioeconomic adversity in early life and risk of depression at 18 years: The mediating role of locus of control

2015 ◽  
Vol 183 ◽  
pp. 269-278 ◽  
Author(s):  
Iryna Culpin ◽  
Lexine Stapinski ◽  
Ömür Budanur Miles ◽  
Ricardo Araya ◽  
Carol Joinson
Keyword(s):  
Locus Of Control ◽  
Early Life ◽  
Mediating Role
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