Group Intervention ‘Drop it!’ Decreases Repetitive Negative Thinking in Major Depressive Disorder and/or Generalized Anxiety Disorder: A Randomised Controlled Study

2021 ◽  
Author(s):  
Roland Rogiers ◽  
Chris Baeken ◽  
Dirk Van den Abbeele ◽  
Edward R. Watkins ◽  
Jonathan Remue ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Anxiety Disorder ◽  
Group Intervention ◽  
Controlled Study ◽  
Generalized Anxiety ◽  
Repetitive Negative Thinking ◽  
Major Depressive ◽  
Negative Thinking ◽  
Randomised Controlled Study ◽  
Randomised Controlled

scholarly journals Disorder-specific cognitive profiles in major depressive disorder and generalized anxiety disorder

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Sanne M Hendriks ◽  
Carmilla MM Licht ◽  
Jan Spijker ◽  
Aartjan TF Beekman ◽  
Florian Hardeveld ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Anxiety Disorder ◽  
Depressive Disorder ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety ◽  
Cognitive Profiles ◽  
Major Depressive

scholarly journals An Underlying Common Factor, Influenced by Genetics and Unique Environment, Explains the Covariation Between Major Depressive Disorder, Generalized Anxiety Disorder, and Burnout: A Swedish Twin Study

2016 ◽  
Vol 19 (6) ◽  
pp. 619-627 ◽  
Author(s):  
Lisa Mather ◽  
Victoria Blom ◽  
Gunnar Bergström ◽  
Pia Svedberg
Keyword(s):  
Risk Factors ◽  
Major Depressive Disorder ◽  
Anxiety Disorder ◽  
Environmental Factors ◽  
Depressive Disorder ◽  
Generalized Anxiety Disorder ◽  
Common Factor ◽  
Generalized Anxiety ◽  
Major Depressive ◽  
Common Pathway

Depression and anxiety are highly comorbid due to shared genetic risk factors, but less is known about whether burnout shares these risk factors. We aimed to examine whether the covariation between major depressive disorder (MDD), generalized anxiety disorder (GAD), and burnout is explained by common genetic and/or environmental factors. This cross-sectional study included 25,378 Swedish twins responding to a survey in 2005–2006. Structural equation models were used to analyze whether the trait variances and covariances were due to additive genetics, non-additive genetics, shared environment, and unique environment. Univariate analyses tested sex limitation models and multivariate analysis tested Cholesky, independent pathway, and common pathway models. The phenotypic correlations were 0.71 (0.69–0.74) between MDD and GAD, 0.58 (0.56–0.60) between MDD and burnout, and 0.53 (0.50–0.56) between GAD and burnout. Heritabilities were 45% for MDD, 49% for GAD, and 38% for burnout; no statistically significant sex differences were found. A common pathway model was chosen as the final model. The common factor was influenced by genetics (58%) and unique environment (42%), and explained 77% of the variation in MDD, 69% in GAD, and 44% in burnout. GAD and burnout had additive genetic factors unique to the phenotypes (11% each), while MDD did not. Unique environment explained 23% of the variability in MDD, 20% in GAD, and 45% in burnout. In conclusion, the covariation was explained by an underlying common factor, largely influenced by genetics. Burnout was to a large degree influenced by unique environmental factors not shared with MDD and GAD.

scholarly journals Are Different Forms of Repetitive Negative Thinking Associated With Interpretation Bias in Generalized Anxiety Disorder and Depression?

2019 ◽  
Vol 7 (5) ◽  
pp. 969-981 ◽  
Author(s):  
Charlotte Krahé ◽  
Jessica Whyte ◽  
Livia Bridge ◽  
Sofia Loizou ◽  
Colette R. Hirsch
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Cognitive Processing ◽  
Cross Sectional Study ◽  
Interpretation Bias ◽  
Generalized Anxiety ◽  
Repetitive Negative Thinking ◽  
Cross Sectional ◽  
Negative Thinking ◽  
Negative Thought

Worry and rumination, two forms of repetitive negative thinking (RNT), are prevalent in generalized anxiety disorder (GAD) and depression. Cognitive processing biases, especially the tendency to draw negative conclusions from ambiguous information (interpretation bias), may maintain worry and rumination. Yet the relationship between interpretation bias and both forms of RNT has not been explored in clinical versus nonclinical samples. In this cross-sectional study, participants with GAD ( n = 72), depression ( n = 79), or neither disorder ( n = 71) completed two tasks assessing interpretation bias, measures of worry and rumination, and reported negative thought intrusions during a behavioral task. Interpretation bias was associated with higher levels of worry, rumination, and negative thought intrusions. Both clinical groups generated significantly more negative interpretations than healthy comparison participants. These findings link interpretation bias to worry and rumination and establish the need for research investigating the causal role of interpretation bias in maintaining RNT.

scholarly journals Standards for Socially-and Achievement-Oriented Roles in Major Depressive Disorder and Generalized Anxiety Disorder

2020 ◽  
Vol 44 (5) ◽  
pp. 1025-1033
Author(s):  
Renee J. Thompson ◽  
Jenna B. Borenstein ◽  
Katharina Kircanski ◽  
Ian H. Gotlib
Keyword(s):  
Major Depressive Disorder ◽  
Anxiety Disorder ◽  
Depressive Disorder ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety ◽  
Major Depressive

Women With Generalized Anxiety Disorder Show Increased Repetitive Negative Thinking During the Luteal Phase of the Menstrual Cycle

2020 ◽  
Vol 8 (6) ◽  
pp. 1037-1045
Author(s):  
Sophie H. Li ◽  
Thomas F. Denson ◽  
Bronwyn M. Graham
Keyword(s):  
Anxiety Disorder ◽  
Menstrual Cycle ◽  
Negative Affect ◽  
Generalized Anxiety Disorder ◽  
Cognitive Processes ◽  
Luteal Phase ◽  
Anxiety Symptoms ◽  
Generalized Anxiety ◽  
Repetitive Negative Thinking ◽  
Negative Thinking

Repetitive negative thinking (RNT) is a transdiagnostic feature of psychiatric disorders. Women report greater RNT than do men, yet the association between uniquely female characteristics, such as fluctuating sex hormones during the menstrual cycle, and RNT has not been established. Here we examined changes in RNT and anxiety symptoms across the menstrual cycle in women with ( n = 40) and without ( n = 41) generalized anxiety disorder (GAD). Women with GAD reported an increase in RNT and negative affect from the follicular phase to the luteal phase; unexpectedly, this was not associated with changes in anxiety symptoms, estradiol, or progesterone. Nonanxious women reported no changes in RNT or anxiety symptoms over the menstrual cycle, but higher within-participants progesterone was associated with reduced RNT and negative affect. These results indicate that uniquely female biological processes may influence core cognitive processes that underlie anxiety disorders, but further investigations to determine the implications for symptom severity are required.

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