KISS-1, Mediated by Promoter Methylation, Suppresses Esophageal Squamous Cell Carcinoma Metastasis via MMP2/9/MAPK Axis

2022 ◽  
Author(s):  
Houyu Duan ◽  
Xiang Ding ◽  
Hesheng Luo
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Promoter Methylation ◽  
Carcinoma Metastasis

scholarly journals Analysis of SEPT9 Gene Promoter Methylation Status in Esophageal Squamous Cell Carcinoma

2020 ◽  
Author(s):  
Aida Mirza Aghasi ◽  
Saied Ghorbian
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Promoter Methylation ◽  
Methylation Status ◽  
Gene Promoter ◽  
Sodium Metabisulfite ◽  
Significant Difference ◽  
Cancer Tissues

Introduction: The changes in the level of SEPT9 gene promoter methylation can contribute to the formation of esophageal squamous cell carcinoma. The aim of this study was to evaluate the level of changes in the level of SEPT9 gene promoter methylation in the esophageal squamous cell carcinoma. Methods: In the present case-control study, we collected 75 paraffin blocks of esophageal cancer tissues and 75 paraffin blocks healthy tissues, which were referred to the Noor-E-Nejat and Tabriz International Hospitals during 2013-2017. After DNA extraction and treatment with sodium metabisulfite, the changes of SEPT9 gene promoter methylation assessed using high resolution melting (HRM) technique. The data were analyzed by SPSS 22 and Chi-square test. Results: Our findings did not show a statistically significant difference between the changes of SEPT9 gene promoter methylation in cancer tissues compared to the healthy tissues (P=0.106). Conclusion: This study shows that SEPT9 gene promoter methylation cannot contribute to the esophageal squamous cell carcinoma cancerogenesis.  

SERPINE2 promotes esophageal squamous cell carcinoma metastasis by activating BMP4

2020 ◽  
Vol 469 ◽  
pp. 390-398 ◽  
Author(s):  
Jianglan Zhang ◽  
Aiping luo ◽  
Furong Huang ◽  
Tongyang Gong ◽  
Zhihua Liu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Carcinoma Metastasis

PGP9.5 Promoter Methylation Is an Independent Prognostic Factor for Esophageal Squamous Cell Carcinoma

2005 ◽  
Vol 65 (11) ◽  
pp. 4963-4968 ◽  
Author(s):  
Diana L. Mandelker ◽  
Keishi Yamashita ◽  
Yutaka Tokumaru ◽  
Koshi Mimori ◽  
David L. Howard ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factor ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Promoter Methylation ◽  
Independent Prognostic Factor

scholarly journals Prognostic value of MLH1 promoter methylation in male patients with esophageal squamous cell carcinoma

2017 ◽  
Vol 13 (4) ◽  
pp. 2745-2750 ◽  
Author(s):  
Dongping Wu ◽  
Xiaoying Chen ◽  
Yan Xu ◽  
Haiyong Wang ◽  
Guangmao Yu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Promoter Methylation ◽  
Prognostic Value ◽  
Mlh1 Promoter ◽  
Male Patients

scholarly journals Promoter methylation of tumor suppressor genes in esophageal squamous cell carcinoma

2013 ◽  
Vol 32 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Ji-Sheng Li ◽  
Jian-Ming Ying ◽  
Xiu-Wen Wang ◽  
Zhao-Hui Wang ◽  
Qian Tao ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Tumor Suppressor ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Promoter Methylation ◽  
Tumor Suppressor Genes ◽  
Suppressor Genes

scholarly journals Promoter Methylation of MGMT Gene in Serum of Patients with Esophageal Squamous Cell Carcinoma in North East India

2014 ◽  
Vol 15 (22) ◽  
pp. 9955-9960 ◽  
Author(s):  
Mandakini Das ◽  
Santanu Kumar Sharma ◽  
Gaganpreet Singh Sekhon ◽  
Bhaskar Jyoti Saikia ◽  
Jagadish Mahanta ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Promoter Methylation ◽  
Mgmt Gene ◽  
North East India ◽  
North East
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