scholarly journals The association between androgen receptor gene CAG polymorphism and polycystic ovary syndrome: a case-control study and meta-analysis

2014 ◽  
Vol 31 (9) ◽  
pp. 1211-1219 ◽  
Author(s):  
Cui Ying Peng ◽  
Hui Jun Xie ◽  
Zi Fen Guo ◽  
Yu Lin Nie ◽  
Jun Chen ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Case Control Study ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Receptor Gene ◽  
Androgen Receptor Gene ◽  
Case Control ◽  
Ovary Syndrome ◽  
Cag Polymorphism ◽  
Control Study

Association of the CAG repeat polymorphisms in androgen receptor gene with polycystic ovary syndrome: A systemic review and meta-analysis

Gene ◽  
2013 ◽  
Vol 524 (2) ◽  
pp. 161-167 ◽  
Author(s):  
Tao Zhang ◽  
Wenqing Liang ◽  
Min Fang ◽  
Jianmin Yu ◽  
Ya Ni ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Receptor Gene ◽  
Androgen Receptor Gene ◽  
Cag Repeat ◽  
Systemic Review ◽  
Ovary Syndrome

scholarly journals A case-control study of the androgen receptor gene CAG repeat polymorphism in Australian prostate carcinoma subjects

Cancer ◽  
2001 ◽  
Vol 92 (4) ◽  
pp. 941-949 ◽  
Author(s):  
Jonathan Beilin ◽  
Laurence Harewood ◽  
Mark Frydenberg ◽  
Hedy Mameghan ◽  
Raymond F. Martyres ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Prostate Carcinoma ◽  
Case Control Study ◽  
Receptor Gene ◽  
Androgen Receptor Gene ◽  
Case Control ◽  
Cag Repeat ◽  
Repeat Polymorphism ◽  
Control Study

scholarly journals CAG and GGN Repeat Length Polymorphisms of Androgen Receptor Gene in Women with Breast Cancer: A Case-Control Study from South India

2012 ◽  
Vol 03 (05) ◽  
pp. 741-748
Author(s):  
Durgadatta Tosh ◽  
Bineet Panda ◽  
Tipirisetti Nageswar Rao ◽  
Arvind Babu ◽  
Vishnupriya Satti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
South India ◽  
Case Control Study ◽  
Receptor Gene ◽  
Androgen Receptor Gene ◽  
Case Control ◽  
Repeat Length ◽  
Length Polymorphisms ◽  
Control Study

scholarly journals Androgen receptor gene methylation related to colorectal cancer risk

2019 ◽  
Vol 8 (7) ◽  
pp. 979-987 ◽  
Author(s):  
Tingting Xia ◽  
Hongru Sun ◽  
Hao Huang ◽  
Haoran Bi ◽  
Rui Pu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Androgen Receptor ◽  
High Resolution Melting ◽  
Case Control Study ◽  
Receptor Gene ◽  
Methylation Status ◽  
Androgen Receptor Gene ◽  
Case Control ◽  
Gene Methylation ◽  
Control Study

According to its incidence patterns, colorectal cancer (CRC) tends to occur more frequently in males than in females, and the evidence shows that CRC is a hormone-related tumor. These findings indicate that androgen receptor (AR) gene methylation might be important for the regulation of the CRC risk in the different sexes. We used a case–control study to investigate the association between AR methylation in peripheral blood (PBL) and CRC risk. A cohort study was conducted to analyze the effect of AR methylation levels in both PBL and tissue on the prognosis of CRC. AR methylation levels were detected using methylation-sensitive high-resolution melting (MS-HRM). The results indicate that the hypomethylation of AR was significantly associated with the risk of CRC (OR = 1.869, 95% CI: 1.629–2.141, P < 0.001), and the results remained similar after adjusting for the propensity score (PS) (OR = 1.344, 95% CI: 1.147–1.575, P < 0.001) and PS matching (OR = 1.138, 95% CI: 1.000–1.292 P = 0.049). The hypomethylation of AR was significantly associated with CRC in males (OR = 2.309, 95% CI: 1.200–4.245; P = 0.012) but not females (OR = 1.000, 95% CI: 0.567–1.765; P = 0.999). The methylation status of AR in PBL and tissue does not seem to be associated with prognosis in colorectal cancer (OR = 1.425, 95% CI: 0.895–2.269, P = 0.135; OR = 0.930, 95% CI: 0.674–1.285, P = 0.661). We conclude that AR hypomethylation in PBL is associated with a high risk of CRC and may serve as a biomarker. Further studies involving large sample sizes are needed to validate the results of this study.

scholarly journals Association of vitamin D receptor gene variants with polycystic ovary syndrome: A case control study

2015 ◽  
Vol 13 (12) ◽  
pp. 793-800 ◽  
Author(s):  
Touraj Mahmoudi ◽  
Keivan Majidzadeh ◽  
Hamid Farahani ◽  
Mojgan Mirakhorli ◽  
Reza Dabiri ◽  
...  
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Case Control Study ◽  
Polycystic Ovary ◽  
Receptor Gene ◽  
Case Control ◽  
Vitamin D Receptor Gene ◽  
Gene Variants ◽  
Ovary Syndrome ◽  
Control Study

Carotid atherosclerosis in women with polycystic ovary syndrome: Initial results from a case-control study

1996 ◽  
Vol 174 (4) ◽  
pp. 1224-1232 ◽  
Author(s):  
David S. Guzick ◽  
Evelyn O. Talbott ◽  
Kim Sutton-Tyrrell ◽  
Holly C. Herzog ◽  
Lewis H. Kuller ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Carotid Atherosclerosis ◽  
Case Control Study ◽  
Polycystic Ovary ◽  
Case Control ◽  
Ovary Syndrome ◽  
Initial Results ◽  
Control Study
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