Ultrasensitive label-free electrical detection of charged biomolecules using a metal–semiconductor–metal Schottky silicon nanowire biristor

Author(s):  
Shaleen ◽  
Sangeeta Singh ◽  
Pankaj Kumar
2014 ◽  
Vol 6 (22) ◽  
pp. 20378-20384 ◽  
Author(s):  
Na Lu ◽  
Pengfei Dai ◽  
Anran Gao ◽  
Jari Valiaho ◽  
Pasi Kallio ◽  
...  

2016 ◽  
Vol 60 (1) ◽  
pp. 81-90 ◽  
Author(s):  
Vivek Pachauri ◽  
Sven Ingebrandt

Biologically sensitive field-effect transistors (BioFETs) are one of the most abundant classes of electronic sensors for biomolecular detection. Most of the time these sensors are realized as classical ion-sensitive field-effect transistors (ISFETs) having non-metallized gate dielectrics facing an electrolyte solution. In ISFETs, a semiconductor material is used as the active transducer element covered by a gate dielectric layer which is electronically sensitive to the (bio-)chemical changes that occur on its surface. This review will provide a brief overview of the history of ISFET biosensors with general operation concepts and sensing mechanisms. We also discuss silicon nanowire-based ISFETs (SiNW FETs) as the modern nanoscale version of classical ISFETs, as well as strategies to functionalize them with biologically sensitive layers. We include in our discussion other ISFET types based on nanomaterials such as carbon nanotubes, metal oxides and so on. The latest examples of highly sensitive label-free detection of deoxyribonucleic acid (DNA) molecules using SiNW FETs and single-cell recordings for drug screening and other applications of ISFETs will be highlighted. Finally, we suggest new device platforms and newly developed, miniaturized read-out tools with multichannel potentiometric and impedimetric measurement capabilities for future biomedical applications.


2012 ◽  
Vol 209 (5) ◽  
pp. 925-934 ◽  
Author(s):  
Maryam H. Abouzar ◽  
Arshak Poghossian ◽  
Andrey G. Cherstvy ◽  
Angela M. Pedraza ◽  
Sven Ingebrandt ◽  
...  

2019 ◽  
Vol 30 (18) ◽  
pp. 184002 ◽  
Author(s):  
Ganesh Jayakumar ◽  
Maxime Legallais ◽  
Per-Erik Hellström ◽  
Mireille Mouis ◽  
Isabelle Pignot-Paintrand ◽  
...  

2015 ◽  
Vol 4 ◽  
pp. 103-108 ◽  
Author(s):  
Elissa H. Williams ◽  
Jong-Yoon Ha ◽  
Melanie Juba ◽  
Barney Bishop ◽  
Sergiy Krylyuk ◽  
...  

2013 ◽  
Vol 23 (18) ◽  
pp. 2301-2307 ◽  
Author(s):  
Cheng-Te Lin ◽  
Phan Thi Kim Loan ◽  
Tzu-Yin Chen ◽  
Keng-Ku Liu ◽  
Chang-Hsiao Chen ◽  
...  

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