Label-free electrical detection of DNA by means of field-effect nanoplate capacitors: Experiments and modeling

2012 ◽  
Vol 209 (5) ◽  
pp. 925-934 ◽  
Author(s):  
Maryam H. Abouzar ◽  
Arshak Poghossian ◽  
Andrey G. Cherstvy ◽  
Angela M. Pedraza ◽  
Sven Ingebrandt ◽  
...  
2012 ◽  
Vol 2 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Jee-Yeon Kim ◽  
Jae-Hyuk Ahn ◽  
Dong-Il Moon ◽  
Sungho Kim ◽  
Tae Jung Park ◽  
...  

2013 ◽  
Vol 1 (1) ◽  
pp. 51-54 ◽  
Author(s):  
Sho Hideshima ◽  
Shofarul Wustoni ◽  
Shigeki Kuroiwa ◽  
Takuya Nakanishi ◽  
Ayumi Koike-Takeshita ◽  
...  

2017 ◽  
Vol 84 (10) ◽  
Author(s):  
Thomas S. Bronder ◽  
Arshak Poghossian ◽  
Michael Keusgen ◽  
Michael J. Schöning

AbstractIn this study, polyelectrolyte-modified field-effect-based electrolyte-insulator-semiconductor (EIS) devices have been used for the label-free electrical detection of double-stranded deoxyribonucleic acid (dsDNA) molecules. The sensor-chip functionalization with a positively charged polyelectrolyte layer provides the possibility of direct adsorptive binding of negatively charged target DNA oligonucleotides onto the SiO


The Analyst ◽  
2012 ◽  
Vol 137 (6) ◽  
pp. 1351 ◽  
Author(s):  
Grace M. Credo ◽  
Xing Su ◽  
Kai Wu ◽  
Oguz H. Elibol ◽  
David J. Liu ◽  
...  

Nano Research ◽  
2015 ◽  
Vol 8 (7) ◽  
pp. 2340-2350 ◽  
Author(s):  
Doo-Won Lee ◽  
Jinhwan Lee ◽  
Il Yung Sohn ◽  
Bo-Yeong Kim ◽  
Young Min Son ◽  
...  

2009 ◽  
Vol 1203 ◽  
Author(s):  
Matthias Bäcker ◽  
Arshak Poghossian ◽  
Maryam H. Abouzar ◽  
Sylvia Wenmackers ◽  
Stoffel D. Janssens ◽  
...  

AbstractCapacitive field-effect electrolyte-diamond-insulator-semiconductor (EDIS) structures with O-terminated nanocrystalline diamond (NCD) as sensitive gate material have been realized and investigated for the detection of pH, penicillin concentration, and layer-by-layer adsorption of polyelectrolytes. The surface oxidizing procedure of NCD thin films as well as the seeding and NCD growth process on a Si-SiO2 substrate have been improved to provide high pH-sensitive, non-porous thin films without damage of the underlying SiO2 layer and with a high coverage of O-terminated sites. The NCD surface topography, roughness, and coverage of the surface groups have been characterized by SEM, AFM and XPS methods. The EDIS sensors with O-terminated NCD film treated in oxidizing boiling mixture for 45 min show a pH sensitivity of about 50 mV/pH. The pH-sensitive properties of the NCD have been used to develop an EDIS-based penicillin biosensor with high sensitivity (65-70 mV/decade in the concentration range of 0.25-2.5 mM penicillin G) and low detection limit (5 μM). The results of label-free electrical detection of layer-by-layer adsorption of charged polyelectrolytes are presented, too.


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