Release characteristics and antibacterial activity of solid state eugenol/β-cyclodextrin inclusion complex

2011 ◽  
Vol 71 (1-2) ◽  
pp. 207-213 ◽  
Author(s):  
Ting Wang ◽  
Bin Li ◽  
Hongyan Si ◽  
Li Lin ◽  
Li Chen
Keyword(s):  
Antibacterial Activity ◽  
Solid State ◽  
Inclusion Complex ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex

Solid-state characterization of sertraline base–β-cyclodextrin inclusion complex

2015 ◽  
Vol 107 ◽  
pp. 265-272 ◽  
Author(s):  
Noriko Ogawa ◽  
Takuro Hashimoto ◽  
Takayuki Furuishi ◽  
Hiromasa Nagase ◽  
Tomohiro Endo ◽  
...  
Keyword(s):  
Solid State ◽  
Inclusion Complex ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex ◽  
Solid State Characterization

scholarly journals Grinding as Solvent-Free Green Chemistry Approach for Cyclodextrin Inclusion Complex Preparation in the Solid State

Pharmaceutics ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 189 ◽  
Author(s):  
Mario Jug ◽  
Paola Mura
Keyword(s):  
Solid State ◽  
Inclusion Complex ◽  
Physicochemical Characteristics ◽  
Solvent Free ◽  
Cyclodextrin Inclusion ◽  
Complex Preparation ◽  
Critical Process Parameters ◽  
Cyclodextrin Inclusion Complex ◽  
Critical Process ◽  
Selection Of

Among the different techniques proposed for preparing cyclodextrin inclusion complex in the solid state, mechanochemical activation by grinding appears as a fast, highly efficient, convenient, versatile, sustainable, and eco-friendly solvent-free method. This review is intended to give a systematic overview of the currently available data in this field, highlighting both the advantages as well as the shortcomings of such an approach. The possible mechanisms involved in the inclusion complex formation in the solid state, by grinding, have been illustrated. For each type of applied milling device, the respective process variables have been examined and discussed, together with the characteristics of the obtained products, also in relation with the physicochemical characteristics of both the drug and cyclodextrin subjected to grinding. The critical process parameters were evidenced in order to provide a useful guide for a rational selection of the most suitable conditions for an efficient inclusion complex preparation by grinding, with the final purpose of promoting a wider use of this effective solvent-free cyclodextrin inclusion complex preparation method in the solid state.

Diastereotopic group recognition in the solid state — A unique intramolecular β-cyclodextrin inclusion complex

2001 ◽  
Vol 79 (11) ◽  
pp. 1806-1811
Author(s):  
Manfred T Reetz ◽  
Joachim Rudolph ◽  
Richard Goddard
Keyword(s):  
Crystal Structure ◽  
Solid State ◽  
Inclusion Complex ◽  
Supramolecular Chemistry ◽  
Structure Analysis ◽  
Crystal Structure Analysis ◽  
Close Vicinity ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex ◽  
First Time

The phenomenon of diastereotopic group recognition has been structurally documented for the first time. A diphenylphosphine-modified β-cyclodextrin having two diastereotopic phenyl groups in close vicinity to the inner cavity of this host was prepared. The crystal structure analysis reveals selective intramolecular complexation of one of the two diastereotopic phenyl groups.Key words: supramolecular chemistry, stereotopic group recognition, cyclodextrins, intramolecular complexation.

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