Rapid Weight Gain During the First Year of Life Predicts Obesity in 2–3 Year Olds from a Low-income, Minority Population

2009 ◽  
Vol 34 (5) ◽  
pp. 370-375 ◽  
Author(s):  
L. Suzanne Goodell ◽  
Dorothy B. Wakefield ◽  
Ann M. Ferris
Author(s):  
Charles T. Wood ◽  
Whitney P. Witt ◽  
Asheley C. Skinner ◽  
Hsiang S. Yin ◽  
Russell L. Rothman ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2412
Author(s):  
Sonia González ◽  
Marta Selma-Royo ◽  
Silvia Arboleya ◽  
Cecilia Martínez-Costa ◽  
Gonzalo Solís ◽  
...  

The early life gut microbiota has been reported to be involved in neonatal weight gain and later infant growth. Therefore, this early microbiota may constitute a target for the promotion of healthy neonatal growth and development with potential consequences for later life. Unfortunately, we are still far from understanding the association between neonatal microbiota and weight gain and growth. In this context, we evaluated the relationship between early microbiota and weight in a cohort of full-term infants. The absolute levels of specific fecal microorganisms were determined in 88 vaginally delivered and 36 C-section-delivered full-term newborns at 1 month of age and their growth up to 12 months of age. We observed statistically significant associations between the levels of some early life gut microbes and infant weight gain during the first year of life. Classifying the infants into tertiles according to their Staphylococcus levels at 1 month of age allowed us to observe a significantly lower weight at 12 months of life in the C-section-delivered infants from the highest tertile. Univariate and multivariate models pointed out associations between the levels of some fecal microorganisms at 1 month of age and weight gain at 6 and 12 months. Interestingly, these associations were different in vaginally and C-section-delivered babies. A significant direct association between Staphylococcus and weight gain at 1 month of life was observed in vaginally delivered babies, whereas in C-section-delivered infants, lower Bacteroides levels at 1 month were associated with higher later weight gain (at 6 and 12 months). Our results indicate an association between the gut microbiota and weight gain in early life and highlight potential microbial predictors for later weight gain.


2020 ◽  
Vol 140 ◽  
pp. 104889
Author(s):  
Lilac Lev-Ari ◽  
Rachel Bachner-Melman ◽  
Ada H. Zohar ◽  
Richard Ebstein ◽  
David Mankuta

2017 ◽  
Vol 12 (5) ◽  
pp. 5-11
Author(s):  
R.N. Trefilov ◽  
◽  
L.V. Sofronova ◽  
R.M. Akhmedova ◽  
◽  
...  

1980 ◽  
Vol 26 (3) ◽  
pp. 96-98 ◽  
Author(s):  
M. D. FROOZANI ◽  
H. MALEKAFZALI ◽  
B. BAHRINI

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Maria Helena Valente ◽  
Filumena Maria da Silva Gomes ◽  
Isabela Judith Martins Benseñor ◽  
Alexandra Valéria Maria Brentani ◽  
Ana Maria de Ulhôa Escobar ◽  
...  

Background and Objectives.Adverse conditions in the prenatal environment and in the first years of life are independently associated with increased risk for cardiovascular disease. This paper aims to study the relation between birthweight, growth in the first year of life, and subclinical atherosclerosis in adults.Methods.88 adults aged between 20 and 31 were submitted to sociodemographic qualities, anthropometric data, blood pressure measurements, metabolic profile, and evaluation of subclinical atherosclerosis.Results.Birthweight <2,500 grams (g) was negatively correlated with (a) increased waist-to-hip ratio (WHR), according to regression coefficient (RC) equal to −0.323, 95% CI [−0.571, −0.075]P<0.05; (b) diastolic blood pressure (RC = −4.744, 95% CI [−9.017, −0.470]P<0.05); (c) low HDL-cholesterol (RC = −0.272, 95% CI [−0.516, −0.029]P<0.05); (d) frequency of intima-media thickness (IMT) of left carotid >75th percentile (RC = −0.242, 95% CI [−0.476, −0.008]P<0.05). Birthweight >3,500 g was associated with (a) BMI >25.0 kg/m2, (RC = 0.317, 95% CI [0.782, 0.557]P<0.05); (b) increased waist circumference (RC = 0.284, 95% CI [0.054, 0.513]P<0.05); (c) elevated WHR (RC = 0.280, 95% CI [0.054, 0.505]P<0.05); (d) minimum subcutaneous adipose tissue (SAT) (RC = 4.354, 95% CI [0.821, 7.888]P<0.05); (e) maximum SAT (RC = 7.095, 95% CI [0.608, 13.583]P<0.05); (f) right lobe of the liver side (RC = 6.896, 95% CI [1.946, 11.847]P<0.001); (g) frequency’s right lobe of the liver >75th percentile (RC = 0.361, 95% CI [0.169, 0.552]P<0.001). Weight gain in the first year of life was inversely correlated with (a) mean IMT of left carotid (RC = −0.046, 95% CI [−0.086, −0.006]P<0.05; (b) frequency IMT of left carotid >75th percentile (RC = −0.253, 95% CI [−0.487, −0.018]P<0.05); (c) mean IMT (RC = −0.038, 95% CI [0.073, −0.002]P<0.05); (d) the frequency of the mean IMT >75th percentile (RC = −0.241, 95% CI [−0.442, −0.041]P<0.05).Conclusions.Adults birthweight <2,500 g and >3,500 g and with insufficient weight gain in the first year of life have showed different metabolic phenotypes, but all of them were related to subclinical atherosclerosis.


Sign in / Sign up

Export Citation Format

Share Document