Research advances in the role and pharmaceuticals of ATP-binding cassette transporters in autoimmune diseases

2022 ◽  
Author(s):  
Jun Yu ◽  
Hao Chen ◽  
Jiangmei Xu ◽  
Peng Zhou
Keyword(s):  
Autoimmune Diseases ◽  
Atp Binding ◽  
Atp Binding Cassette Transporters ◽  
Atp Binding Cassette

scholarly journals Stimulation of Cholesterol Excretion by the Liver X Receptor Agonist Requires ATP-binding Cassette Transporters G5 and G8

2003 ◽  
Vol 278 (18) ◽  
pp. 15565-15570 ◽  
Author(s):  
Liqing Yu ◽  
Jennifer York ◽  
Klaus von Bergmann ◽  
Dieter Lutjohann ◽  
Jonathan C. Cohen ◽  
...  
Keyword(s):  
Receptor Agonist ◽  
Liver X Receptor ◽  
Atp Binding ◽  
Atp Binding Cassette Transporters ◽  
Cholesterol Excretion ◽  
Liver X Receptor Agonist ◽  
Stimulation Of ◽  
Atp Binding Cassette

scholarly journals The capacity of Listeria monocytogenes mutants with in-frame deletions in putative ATP-binding cassette transporters to form biofilms and comparison with the wild type

2014 ◽  
Vol 3 (1) ◽  
Author(s):  
Marina Ceruso ◽  
Pina Fratamico ◽  
Claudia Chirollo ◽  
Rosanna Taglialatela ◽  
Maria Luisa Cortesi ◽  
...  
Keyword(s):  
Listeria Monocytogenes ◽  
Atp Binding ◽  
Wild Type ◽  
Atp Binding Cassette Transporters ◽  
Atp Binding Cassette

scholarly journals Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia

2006 ◽  
Vol 5 (8) ◽  
pp. 1986-1994 ◽  
Author(s):  
Thomas Efferth ◽  
Jean-Pierre Gillet ◽  
Axel Sauerbrey ◽  
Felix Zintl ◽  
Vincent Bertholet ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
T Cell ◽  
Expression Profiling ◽  
Lymphoblastic Leukemia ◽  
Atp Binding ◽  
Atp Binding Cassette Transporters ◽  
Cell Acute Lymphoblastic Leukemia ◽  
Atp Binding Cassette

scholarly journals Endocrine Disruptors Differentially Target ATP-Binding Cassette Transporters in the Blood-Testis Barrier and Affect Leydig Cell Testosterone Secretion In Vitro

2013 ◽  
Vol 136 (2) ◽  
pp. 382-391 ◽  
Author(s):  
Anita C. A. Dankers ◽  
Maarke J. E. Roelofs ◽  
Aldert H. Piersma ◽  
Fred C. G. J. Sweep ◽  
Frans G. M. Russel ◽  
...  
Keyword(s):  
Endocrine Disruptors ◽  
Leydig Cell ◽  
Atp Binding ◽  
Testosterone Secretion ◽  
Atp Binding Cassette Transporters ◽  
Blood Testis Barrier ◽  
Atp Binding Cassette

scholarly journals Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters

FEBS Letters ◽  
2001 ◽  
Vol 492 (1-2) ◽  
pp. 66-72 ◽  
Author(s):  
Peter Roerig ◽  
Peter Mayerhofer ◽  
Andreas Holzinger ◽  
Jutta Gärtner
Keyword(s):  
Functional Analysis ◽  
Nucleotide Binding ◽  
Atp Binding ◽  
Atp Binding Cassette Transporters ◽  
Atp Binding Cassette

Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice

2003 ◽  
Vol 38 (6) ◽  
pp. 710-716 ◽  
Author(s):  
Astrid Kosters ◽  
Raoul J.J.M. Frijters ◽  
Frank G. Schaap ◽  
Edwin Vink ◽  
Torsten Plösch ◽  
...  
Keyword(s):  
Atp Binding ◽  
Biliary Cholesterol ◽  
Hepatic Expression ◽  
Atp Binding Cassette Transporters ◽  
Biliary Cholesterol Secretion ◽  
Cholesterol Secretion ◽  
Atp Binding Cassette

scholarly journals Expression of some ATP-binding cassette transporters in acute myeloid leukemia

2017 ◽  
Vol 9 (4) ◽  
Author(s):  
Antonella Maria Salvia ◽  
Flavia Cuviello ◽  
Sabrina Coluzzi ◽  
Roberta Nuccorini ◽  
Immacolata Attolico ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Acute Myeloid Leukemia ◽  
Abc Transporters ◽  
Healthy Subjects ◽  
Myeloid Leukemia ◽  
Resistance Mechanisms ◽  
Atp Binding ◽  
Atp Binding Cassette Transporters ◽  
Acute Myeloid ◽  
Atp Binding Cassette

Hematopoietic cells express ATP binding cassette (ABC) transporters in relation to different degrees of differentiation. One of the known multidrug resistance mechanisms in acute myeloid leukemia (AML) is the overexpression of efflux pumps belonging to the superfamily of ABC transporters such as ABCB1, ABCG2 and ABCC1. Although several studies were carried out to correlate ABC transporters expression with drug resistance, little is known about their role as markers of diagnosis and progression of the disease. For this purpose we investigated the expression, by real-time PCR, of some ABC genes in bone marrow samples of AML patients at diagnosis and after induction therapy. At diagnosis, ABCG2 was always down-regulated, while an up regulated trend for ABCC1 was observed. After therapy the examined genes showed a different expression trend and approached the values of healthy subjects suggesting that this event could be considered as a marker of AML regression. The expression levels of some ABC transporters such as ABCC6, seems to be related to gender, age and to the presence of FLT3/ITD gene mutation.

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