Single nucleotide polymorphisms, haplotypes and combined genotypes of lactoferrin gene and their associations with mastitis in Chinese Holstein cattle

2009 ◽  
Vol 37 (1) ◽  
pp. 477-483 ◽  
Author(s):  
Jinming Huang ◽  
Hongmei Wang ◽  
Changfa Wang ◽  
Jianbin Li ◽  
Qiuling Li ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Holstein Cattle ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Chinese Holstein ◽  
Chinese Holstein Cattle ◽  
Lactoferrin Gene ◽  
Combined Genotypes

Seven novel single nucleotide polymorphisms identified within river buffalo (Bubalus bubalis) lactoferrin gene

2009 ◽  
Vol 42 (5) ◽  
pp. 1021-1026 ◽  
Author(s):  
Periasamy Kathiravan ◽  
Ranjit S. Kataria ◽  
Bishnu P. Mishra ◽  
Praveen K. Dubey ◽  
M. Selvakumar ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Bubalus Bubalis ◽  
River Buffalo ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Lactoferrin Gene

Single nucleotide polymorphisms (SNPs) in human lactoferrin geneThis paper is one of a selection of papers published in this Special Issue, entitled 7th International Conference on Lactoferrin: Structure, Function and Applications, and has undergone the Journal's usual peer review process.

2006 ◽  
Vol 84 (3) ◽  
pp. 381-384 ◽  
Author(s):  
Christina T. Teng ◽  
Wesley Gladwell
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Inflammatory Responses ◽  
Peer Review Process ◽  
Genome Project ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Environmental Health Sciences ◽  
Normal Healthy Individual ◽  
Lactoferrin Gene ◽  
And Function

The lactoferrin protein possesses antimicrobial and antiviral activities. It is also involved in the modulation of the immune response. In a normal healthy individual, lactoferrin plays a role in the front-line host defense against infection and in immune and inflammatory responses. Whether genomic variations, such as single nucleotide polymorphisms (SNPs), have an effect on the structure and function of lactoferrin protein and whether these variations contribute to the different susceptibility of individuals in response to environmental insults are interesting health-related issues. In this study, the lactoferrin gene was resequenced as part of the Environmental Genome Project of the National Institute of Environmental Health Sciences, which operates within the National Institutes of Health. Ninety-one healthy donors of different ethnicities were used to establish common SNPs in the exons of the lactoferrin gene in the general population. The data will serve as a basis from which study the association of lactoferrin polymorphism and disease.

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