scholarly journals Maurocalcine as a Non Toxic Drug Carrier Overcomes Doxorubicin Resistance in the Cancer Cell Line MDA-MB 231

2008 ◽  
Vol 26 (4) ◽  
pp. 836-845 ◽  
Author(s):  
Sonia Aroui ◽  
Narendra Ram ◽  
Florence Appaix ◽  
Michel Ronjat ◽  
Abderraouf Kenani ◽  
...  
Keyword(s):  
Cell Line ◽  
Cancer Cell ◽  
Drug Carrier ◽  
Cancer Cell Line ◽  
Doxorubicin Resistance ◽  
Toxic Drug

scholarly journals Establishment and characterization of a bladder cancer cell line with enhanced doxorubicin resistance by mevalonate pathway activation

Tumor Biology ◽  
2015 ◽  
Vol 36 (5) ◽  
pp. 3293-3300 ◽  
Author(s):  
Annemarie Greife ◽  
Jitka Tukova ◽  
Christine Steinhoff ◽  
Simon D. Scott ◽  
Wolfgang A. Schulz ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Mevalonate Pathway ◽  
Cancer Cell Line ◽  
Bladder Cancer Cell ◽  
Bladder Cancer Cell Line ◽  
Doxorubicin Resistance ◽  
Pathway Activation

scholarly journals Cellular uptake and toxicity of gold nanoparticles in a tumor-like (hypoxic) environment

2021 ◽  
Author(s):  
Mehrnoosh Neshatian
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Cells ◽  
Cell Line ◽  
Cancer Cell ◽  
Drug Carrier ◽  
Cancer Cell Line ◽  
Cervical Cancer Cell Line ◽  
Hypoxic Conditions ◽  
Hypoxic Environment ◽  
Mcf 7

Cancer cells deprived adequate oxygen tension, are called hypoxic cells. Hypoxic shows resistance to both chemotherapy and/or radiotherapy. On the other hand gold Nanoparticles (GNPs) are being used as promising agents in cancer therapy. GNPs can be used as radiosensitizer and drug carrier agents. It also has been show that uptake of GNPs in normal oxygenated (normoxic) cancer cells is maximum for 50 nm GNPs. However, it is important to know the variation in GNPs uptake and toxicity of 50 nm particles in a tumor-like (hypoxic) environment. Hence, we have investigated toxicity and uptake of 50 nm GNPs in hypoxic cancer cells. MCF-7 (breast cancer cell line) and HeLa (cervical cancer cell line), were used in this study. The results of this study showed that uptake of GNPs in hypoxic cells were dependent on the exposure duration to hypoxic conditions. Cancer cells under prolong hypoxia showed highest GNP uptake.

scholarly journals Cellular uptake and toxicity of gold nanoparticles in a tumor-like (hypoxic) environment

2021 ◽  
Author(s):  
Mehrnoosh Neshatian
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Cells ◽  
Cell Line ◽  
Cancer Cell ◽  
Drug Carrier ◽  
Cancer Cell Line ◽  
Cervical Cancer Cell Line ◽  
Hypoxic Conditions ◽  
Hypoxic Environment ◽  
Mcf 7

Cancer cells deprived adequate oxygen tension, are called hypoxic cells. Hypoxic shows resistance to both chemotherapy and/or radiotherapy. On the other hand gold Nanoparticles (GNPs) are being used as promising agents in cancer therapy. GNPs can be used as radiosensitizer and drug carrier agents. It also has been show that uptake of GNPs in normal oxygenated (normoxic) cancer cells is maximum for 50 nm GNPs. However, it is important to know the variation in GNPs uptake and toxicity of 50 nm particles in a tumor-like (hypoxic) environment. Hence, we have investigated toxicity and uptake of 50 nm GNPs in hypoxic cancer cells. MCF-7 (breast cancer cell line) and HeLa (cervical cancer cell line), were used in this study. The results of this study showed that uptake of GNPs in hypoxic cells were dependent on the exposure duration to hypoxic conditions. Cancer cells under prolong hypoxia showed highest GNP uptake.

Overcoming doxorubicin-resistance in the NCI/ADR-RES model cancer cell line by novel anthracene-9,10-dione derivatives

2013 ◽  
Vol 23 (22) ◽  
pp. 6156-6160 ◽  
Author(s):  
Supranee Sangthong ◽  
Helen Ha ◽  
Thapong Teerawattananon ◽  
Nattaya Ngamrojanavanich ◽  
Nouri Neamati ◽  
...  
Keyword(s):  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Doxorubicin Resistance

Ligation of fas antigen stimulates chemoline secretion in pancreatic cancer cell line PANC-1

2001 ◽  
Vol 120 (5) ◽  
pp. A336-A336
Author(s):  
M SHIMADA ◽  
A ANDOH ◽  
Y ARAKI ◽  
Y FUJIYAMA ◽  
T BAMBA
Keyword(s):  
Pancreatic Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Pancreatic Cancer Cell ◽  
Pancreatic Cancer Cell Line ◽  
Cancer Cell Line ◽  
Fas Antigen

624: Usefulness of Cancer Vaccine Therapy Using Bladder Cancer Cell Line Introduced with Interleukin 21 Gene

2006 ◽  
Vol 175 (4S) ◽  
pp. 201-201 ◽  
Author(s):  
Isao Hara ◽  
Junya Furukawa ◽  
Kazuki Yamanaka ◽  
Yuji Yamada ◽  
Masato Fujisawa
Keyword(s):  
Bladder Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Vaccine ◽  
Cancer Cell Line ◽  
Bladder Cancer Cell ◽  
Vaccine Therapy ◽  
Bladder Cancer Cell Line ◽  
Interleukin 21
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