Quality of life of childbearing age women and its associated factors: an application of seemingly unrelated regression (SUR) models

Congenital heart disease (CHD) is a major global health problem. Until recently, the siblings of this group did not receive much attention. This review, conducted from November 2019 to October 2020, aims to summarize knowledge about psychosocial well-being and quality of life (QoL), associated factors, and interventions for siblings of children with CHD. Systematic searches were conducted in PubMed, PsycINFO, PsycARTICLES, Web of Science via EBSCOhost, and CENTRAL. Twelve articles were included. Results showed that psychosocial well-being was impaired in 14% to 40% of siblings. Negative impact of illness was highest for CHD siblings compared to siblings of children with cancer, cystic fibrosis, or diabetes. QoL was impaired in up to one-third. Siblings of children with CHD and cancer rated their QoL lower than those of siblings of children with cystic fibrosis or type-1 diabetes. Associated factors were sibling age, gender, socioeconomic status, miscarriage, previous sibling death, visibility of illness, and severity of condition. Only one of two interventions focused on siblings of CHD children. Although data are scarce and inhomogeneous, it indicates that siblings of CHD children suffer from lower psychosocial well-being and QoL than siblings of children with other chronic conditions. Interventions to improve their situation should be developed.

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Identification of key long-term symptoms and associated factors affecting quality of life after esophagectomy; multi-center European LASER study

European Journal of Surgical Oncology ◽

10.1016/j.ejso.2020.11.210 ◽

2021 ◽

Vol 47 (2) ◽

pp. e25-e26

Author(s):

Sheraz Markar

Keyword(s):

Quality Of Life ◽

Associated Factors ◽

Factors Affecting

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PCV70 Quality of Life Realted to Health and Associated Factors in Men with Indication of Cardiac Rehabilitation (CR) and Erectile Dysfunction.

Value in Health ◽

10.1016/j.jval.2020.08.561 ◽

2020 ◽

Vol 23 ◽

pp. S499

Author(s):

P. Soto-Parada ◽

C. Santibañez ◽

N. Febré

Keyword(s):

Quality Of Life ◽

Erectile Dysfunction ◽

Cardiac Rehabilitation ◽

Associated Factors

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Topical TRPM8 Agonist for Relieving Neuropathic Ocular Pain in Patients with Dry Eye: A Pilot Study

Journal of Clinical Medicine ◽

10.3390/jcm10020250 ◽

2021 ◽

Vol 10 (2) ◽

pp. 250

Author(s):

Hyeon Jeong Yoon ◽

Jonghwa Kim ◽

Jee Myung Yang ◽

Edward T. Wei ◽

Seong Jin Kim ◽

...

Keyword(s):

Quality Of Life ◽

Pilot Study ◽

Pain Intensity ◽

Dry Eye ◽

Associated Factors ◽

Treatment Result ◽

Ocular Pain ◽

Eye Pain ◽

Validated Questionnaire

Background: Activation of TRPM8, a cold-sensing receptor located on the cornea and eyelid, has the potential to relieve the neuropathic ocular pain (NOP) in dry eye (DE) by inhibiting other aberrant nociceptive inputs. We aimed to investigate the effect of a topical TRPM8 agonist, cryosim-3 (C3), on relieving DE-associated NOP. Methods: We conducted a prospective pilot study of 15 patients with DE-associated NOP. These patients applied topical C3 to their eyelid, 4 times/day for 1 month. The patients underwent clinical examinations. They also completed the Ocular Pain Assessment Survey (OPAS), which is a validated questionnaire for NOP, at baseline, 1 week, and 1 month after treatment. Result: At 1 week, the OPAS scores of eye pain intensity, quality of life (driving/watching TV, general activity, sleep, and enjoying life/relations with other people), and associated factors (burning sensation, light sensitivity, and tearing) improved. The total OPAS scores of eye pain intensity, quality of life, and associated factors remained improved at 1 month. The Schirmer test scores also improved at 1 month. Conclusion: TRPM8 agonist (C3) could be a novel agent for treating patients with DE-associated NOP who are unresponsive to conventional treatments.

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