Validation of the Impact Index: can we measure disease effects on quality of life in patients with hip and knee osteoarthritis?

Author(s):  
K. D. Valentine ◽  
S. Brodney ◽  
Ha Vo ◽  
Karen Sepucha ◽  
Floyd J. Fowler ◽  
...  
2013 ◽  
Vol 7 (1) ◽  
pp. 619-623 ◽  
Author(s):  
Jack Farr II ◽  
Larry E. Miller ◽  
Jon E. Block

Knee osteoarthritis (OA) has a significant negative impact on health-related quality of life (HRQoL). Identification of therapies that improve HRQoL in patients with knee OA may mitigate the clinical, economic, and social burden of this disease. The purpose of this commentary is to report the impact of knee OA on HRQoL, describe the change in HRQoL attributable to common knee OA interventions, and summarize findings from clinical trials of a promising therapy. Nonsurgical therapies do not reliably modify HRQoL in knee OA patients given their general inability to alleviate physical manifestations of OA. Surgical knee OA interventions generally result in good to excellent patient outcomes. However, there are significant barriers to considering surgery, which limits clinical utility. Therapies that most effectively control OA-related pain with a low risk: benefit ratio will likely have the greatest benefit on HRQoL with greater rates of patient adoption. Initial clinical trial findings suggest that less invasive joint unloading implants hold promise in bridging the therapeutic gap between nonsurgical and surgical treatments for the knee OA patient.


2019 ◽  
Vol 3 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Yuyu Ishimoto ◽  
Mamoru Kawakami ◽  
Elizabeth Curtis ◽  
Cyrus Cooper ◽  
Nicholas C. Harvey ◽  
...  

2020 ◽  
Vol 29 (4) ◽  
pp. 2097-2108
Author(s):  
Robyn L. Croft ◽  
Courtney T. Byrd

Purpose The purpose of this study was to identify levels of self-compassion in adults who do and do not stutter and to determine whether self-compassion predicts the impact of stuttering on quality of life in adults who stutter. Method Participants included 140 adults who do and do not stutter matched for age and gender. All participants completed the Self-Compassion Scale. Adults who stutter also completed the Overall Assessment of the Speaker's Experience of Stuttering. Data were analyzed for self-compassion differences between and within adults who do and do not stutter and to predict self-compassion on quality of life in adults who stutter. Results Adults who do and do not stutter exhibited no significant differences in total self-compassion, regardless of participant gender. A simple linear regression of the total self-compassion score and total Overall Assessment of the Speaker's Experience of Stuttering score showed a significant, negative linear relationship of self-compassion predicting the impact of stuttering on quality of life. Conclusions Data suggest that higher levels of self-kindness, mindfulness, and social connectedness (i.e., self-compassion) are related to reduced negative reactions to stuttering, an increased participation in daily communication situations, and an improved overall quality of life. Future research should replicate current findings and identify moderators of the self-compassion–quality of life relationship.


2008 ◽  
Author(s):  
Jennifer S. Fabritius ◽  
Lisa S. Doane ◽  
Aileen M. Echiverri ◽  
Shoshana Y. Kahana ◽  
Joshua D. McDavid ◽  
...  
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