scholarly journals Phylogenetic and evolutionary analysis of foot-and-mouth disease virus A/ASIA/Sea-97 lineage

Virus Genes ◽  
2021 ◽  
Author(s):  
Soyeon Bae ◽  
Vladimir Li ◽  
Juyong Hong ◽  
Jin Nam Kim ◽  
Heebal Kim
Keyword(s):  
Southeast Asia ◽  
East Asia ◽  
Disease Virus ◽  
Evolutionary Process ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Evolutionary Analysis ◽  
Amino Acid Residues ◽  
Mouth Disease Virus ◽  
Foot And Mouth

AbstractFoot-and-mouth disease virus (FMDV) A/ASIA/Sea-97 is a predominant lineage in Southeast Asia and East Asia. However, Sea-97 lineage has not been well studied since its first outbreak in Thailand in 1997. Thus, we conducted phylogenetic and evolutionary analysis of Sea-97 using 224 VP1 sequences of FMDV A/ASIA during 1960 and 2018. Phylogenetic analysis revealed that Sea-97 lineage can be classified into five groups (G1–G5). After the emergence of G2 from G1, the genetic diversity of Sea-97 increased sharply, causing divergence into G3, G4 and G5. During this evolutionary process, Sea-97 lineage, which was initially found only in some countries in Southeast Asia, gradually spread to East Asia. The evolution rate of this lineage was estimated to be 1.2 × 10–2 substitutions/site/year and there were many differences in amino acid residues compared to vaccine strain. Substitutions at antigenically important sites may affect the efficacy of the vaccine, suggesting the need for appropriate vaccine strains. Our results could provide meaningful information to understand comprehensive characteristic of Sea-97 lineage.

scholarly journals A56 Evolutionary analyses of foot-and-mouth disease virus in Southeast Asia using whole-genome sequences

2018 ◽  
Vol 4 (suppl_1) ◽  
Author(s):  
Barbara Brito ◽  
Steven J Pauszek ◽  
Ethan J Hartwig ◽  
George R Smoliga ◽  
Le T Vu ◽  
...  
Keyword(s):  
Southeast Asia ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Whole Genome ◽  
Genome Sequences ◽  
Mouth Disease Virus ◽  
Foot And Mouth

scholarly journals Genome Sequence of Foot-and-Mouth Disease Virus of Serotype O Lineage Ind-2001d Isolated from Cattle in Mongolia in 2015

2017 ◽  
Vol 5 (45) ◽  
Author(s):  
Tatsuya Nishi ◽  
Gerelmaa Ulziibat ◽  
Buyantogtokh Khanui ◽  
Odonchimeg Myagmarsuren ◽  
Kazuki Morioka ◽  
...  
Keyword(s):  
Southeast Asia ◽  
Disease Virus ◽  
Genome Sequence ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Serotype O ◽  
Mouth Disease Virus ◽  
Foot And Mouth

ABSTRACT We report the whole-genome sequence of the foot-and-mouth disease virus (FMDV) O/MOG/BU/2-7/2015 isolated in Mongolia in 2015. This virus is closely related to isolates identified in Southeast Asia in 2015 and is classified under the O/ME-SA/Ind-2001d lineage. This is the first detection of an FMDV of this lineage in Mongolia.

Comparative sequence analysis of representative foot-and-mouth disease virus genomes from Southeast Asia

Virus Genes ◽  
2011 ◽  
Vol 43 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Nor Faizah Abdul-Hamid ◽  
Müge Fırat-Saraç ◽  
Alan D. Radford ◽  
Nick J. Knowles ◽  
Donald P. King
Keyword(s):  
Sequence Analysis ◽  
Southeast Asia ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Comparative Sequence Analysis ◽  
Mouth Disease ◽  
Comparative Sequence ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Virus Genomes

scholarly journals First Finding of Southeast Asia Topotype of Foot-and-Mouth Disease Virus in Kinmen, Taiwan, in the 2012 Outbreak

2014 ◽  
Vol 76 (11) ◽  
pp. 1479-1485 ◽  
Author(s):  
Yeou-Liang LIN ◽  
Chia-Yi CHANG ◽  
Chu-Hsiang PAN ◽  
Ming-Chung DENG ◽  
Hsiang-Jung TSAI ◽  
...  
Keyword(s):  
Southeast Asia ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
First Finding ◽  
Mouth Disease Virus ◽  
Foot And Mouth

scholarly journals Evolutionary Analysis of Structural Protein Gene VP1 of Foot-and-Mouth Disease Virus Serotype Asia 1

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Qingxun Zhang ◽  
Xinsheng Liu ◽  
Yuzhen Fang ◽  
Li Pan ◽  
Jianliang Lv ◽  
...  
Keyword(s):  
Positive Selection ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Evolutionary Analysis ◽  
Structural Protein ◽  
Mouth Disease Virus ◽  
Virus Serotype ◽  
Foot And Mouth ◽  
Serotype Asia 1

Foot-and-mouth disease virus (FMDV) serotype Asia 1 was mostly endemic in Asia and then was responsible for economically important viral disease of cloven-hoofed animals, but the study on its selection and evolutionary process is comparatively rare. In this study, we characterized 377 isolates from Asia collected up until 2012, including four vaccine strains. Maximum likelihood analysis suggested that the strains circulating in Asia were classified into 8 different groups (groups I–VIII) or were unclassified (viruses collected before 2000). On the basis of divergence time analyses, we infer that the TMRCA of Asia 1 virus existed approximately 86.29 years ago. The result suggested that the virus had a high mutation rate (5.745 × 10−3substitutions/site/year) in comparison to the other serotypes of FMDV VP1 gene. Furthermore, the structural protein VP1 was under lower selection pressure and the positive selection occurred at many sites, and four codons (positions 141, 146, 151, and 169) were located in known critical antigenic residues. The remaining sites were not located in known functional regions and were moderately conserved, and the reason for supporting all sites under positive selection remains to be elucidated because the power of these analyses was largely unknown.

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