A novel multi-stage preculture strategy of Rhizopus oryzae ME-F12 for fumaric acid production in a stirred-tank reactor

2009 ◽  
Vol 25 (10) ◽  
pp. 1871-1876 ◽  
Author(s):  
Yongqian Fu ◽  
Qing Xu ◽  
Shuang Li ◽  
He Huang ◽  
Yao Chen
BioResources ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. 8197-8204
Author(s):  
Yuchen Ning ◽  
Yang Li ◽  
Shijie Zhao ◽  
Huan Liu ◽  
Li Deng ◽  
...  

The traditional two-step cultivation mode for fungal cultivation is commonly divided into the seed stage (usually 24 to 48 h) and the production stage (usually 96 to 144 h). The use of two stages prolongs the total production cycle and generates excess wastewater. In this work, an efficient and environmentally friendly one-step fermentation method was applied for the production of fumaric acid by immobilized Rhizopus arrhizus in a stirred-tank reactor. The nitrogen source content and the agitation speed of the reactor were optimized as the two critical factors in the one-step fermentation process; the fumaric acid production of 51 g/L with a yield of 0.42 g/g glucose was comparable with the product from the traditional two-step fermentation process. Furthermore, the total production cycle was shortened to 96 h, and the amount of wastewater was reduced due to the avoidance of the seed culture process. Thus, utilization of the one-step fermentation method to produce fumaric acid was shown to be preferable feasibility and environmental-friendliness. This is a promising method for industrial production of fumaric acid and other high-value biochemicals by fungus.


2017 ◽  
Vol 244 ◽  
pp. 929-933 ◽  
Author(s):  
Huan Liu ◽  
Shijie Zhao ◽  
Yuhan Jin ◽  
Xuemin Yue ◽  
Li Deng ◽  
...  

2020 ◽  
Vol 5 (11) ◽  
pp. 2081-2090
Author(s):  
Juri Ilare ◽  
Mattia Sponchioni ◽  
Giuseppe Storti ◽  
Davide Moscatelli

We propose a model for the optimized conversion of semi-continuous poly(acrylic acid) production to continuous preserving the product features.


Author(s):  
Mariela Verónica Catone ◽  
María Mercedes Palomino ◽  
Danilo Mario Legisa ◽  
Joaquina Fina Martin ◽  
Vicente Monedero García ◽  
...  

1979 ◽  
Vol 44 (7) ◽  
pp. 2184-2195
Author(s):  
Vladimír Herles ◽  
Jan Čermák ◽  
Antonín Havlíček

The paper deals with the analysis of the dynamic behavior of the 1st order system with two random parameters. The theoretical results have been compared with experiments on flow model of a stirred tank reactor.


2009 ◽  
Vol 11 (36) ◽  
pp. 7885 ◽  
Author(s):  
Dung L. Che ◽  
Jared D. Smith ◽  
Stephen R. Leone ◽  
Musahid Ahmed ◽  
Kevin R. Wilson

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