Exercise training in heart failure patients: effects on skeletal muscle abnormalities and sympathetic nervous activity—a literature review

2018 ◽  
Vol 14 (2) ◽  
pp. 217-226
Author(s):  
Fotios Iliopoulos ◽  
Nicolas Mazis
Keyword(s):  
Heart Failure ◽  
Skeletal Muscle ◽  
Exercise Training ◽  
Literature Review ◽  
Nervous Activity ◽  
Sympathetic Nervous Activity ◽  
Heart Failure Patients ◽  
Sympathetic Nervous

Increased Central Nervous System Monoamine Neurotransmitter Turnover and Its Association With Sympathetic Nervous Activity in Treated Heart Failure Patients

Circulation ◽  
1995 ◽  
Vol 92 (7) ◽  
pp. 1813-1818 ◽  
Author(s):  
Gavin W. Lambert ◽  
David M. Kaye ◽  
Jeffrey Lefkovits ◽  
Garry L. Jennings ◽  
Andrea G. Turner ◽  
...  
Keyword(s):  
Heart Failure ◽  
Central Nervous System ◽  
Nervous System ◽  
Nervous Activity ◽  
Sympathetic Nervous Activity ◽  
Monoamine Neurotransmitter ◽  
Heart Failure Patients ◽  
Sympathetic Nervous

Norepinephrine spillover from skeletal muscle during exercise in humans: role of muscle mass

1989 ◽  
Vol 257 (6) ◽  
pp. H1812-H1818 ◽  
Author(s):  
G. K. Savard ◽  
E. A. Richter ◽  
S. Strange ◽  
B. Kiens ◽  
N. J. Christensen ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Blood Flow ◽  
Muscle Mass ◽  
Nervous Activity ◽  
Plasma Concentrations ◽  
Whole Body ◽  
Knee Extensors ◽  
Sympathetic Nervous Activity ◽  
Leg Blood Flow ◽  
Sympathetic Nervous

The purpose of this study was to determine the effect of increasing muscle mass involvement in dynamic exercise on both sympathetic nervous activation and local hemodynamic variables of individual active and inactive skeletal muscle groups. Six male subjects performed 15-min bouts of one-legged knee extension either alone or in combination with the knee extensors of the other leg and/or with the arms. The range of work intensities varied between 24 and 71% (mean) of subjects' maximal aerobic capacity (% VO2max). Leg blood flow, measured in the femoral vein by thermodilution, was determined in both legs. Arterial and venous plasma concentrations of norepinephrine (NE) and epinephrine were analyzed, and the calculated NE spillover was used as an index of sympathetic nervous activity to the limb. NE spillover increased gradually both in the resting, and to a larger extent in the exercising legs, with a steeper rise occurring approximately 70% VO2max. These increases were not associated with any significant changes in leg blood flow or leg vascular conductance at the exercise intensities examined. These results suggest that, as the total active muscle mass increases, the rise in sympathetic nervous activity to skeletal muscle, either resting or working at a constant load, is not associated with any significant neurogenic vasoconstriction and reduction in flow or conductance through the muscle vascular bed, during whole body exercise demanding up to 71% VO2max.

scholarly journals Exercise Training Alters Skeletal Muscle Mitochondrial Morphometry in Heart Failure Patients

2002 ◽  
Vol 9 (6) ◽  
pp. 377-381 ◽  
Author(s):  
C. Santoro ◽  
A. Cosmas ◽  
D. Forman ◽  
A. Morghan ◽  
L. Bairos ◽  
...  
Keyword(s):  
Heart Failure ◽  
Skeletal Muscle ◽  
Exercise Training ◽  
Heart Failure Patients
Sign in / Sign up

Export Citation Format

Share Document