Short-term exposure to particulate matter on heart rate variability in humans: a systematic review of crossover and controlled studies

2021 ◽  
Author(s):  
Fangfang Huang ◽  
Yuhan Zhao ◽  
Ping Wang ◽  
Yingfang Wang ◽  
Licheng Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Particulate Matter ◽  
Short Term ◽  
Short Term Exposure

scholarly journals Acute effect of ambient fine particulate matter on heart rate variability: an updated systematic review and meta-analysis of panel studies

2020 ◽  
Vol 25 (1) ◽  
Author(s):  
Zhiping Niu ◽  
Feifei Liu ◽  
Baojing Li ◽  
Na Li ◽  
Hongmei Yu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Particulate Matter ◽  
Meta Analysis ◽  
Acute Effect ◽  
Short Term ◽  
Short Term Exposure ◽  
Panel Studies ◽  
Frequency Power

Abstract Background Decreased heart rate variability (HRV) is a predictor of autonomic system dysfunction, and is considered as a potential mechanism of increased risk of cardiovascular disease (CVD) induced by exposure to particulate matter less than 2.5 μm in diameter (PM2.5). Previous studies have suggested that exposure to PM2.5 may lead to decreased HRV levels, but the results remain inconsistent. Methods An updated systematic review and meta-analysis of panel studies till November 1, 2019 was conducted to evaluate the acute effect of exposure to ambient PM2.5 on HRV. We searched electronic databases (PubMed, Web of Science, and Embase) to identify panel studies reporting the associations between exposure to PM2.5 and the four indicators of HRV (standard deviation of all normal-to-normal intervals (SDNN), root mean square of successive differences in adjacent normal-to-normal intervals (rMSSD), high frequency power (HF), and low frequency power (LF)). Random-effects model was used to calculate the pooled effect estimates. Results A total of 33 panel studies were included in our meta-analysis, with 16 studies conducted in North America, 12 studies in Asia, and 5 studies in Europe. The pooled results showed a 10 μg/m3 increase in PM2.5 exposure which was significantly associated with a − 0.92% change in SDNN (95% confidence intervals (95%CI) − 1.26%, − 0.59%), − 1.47% change in rMSSD (95%CI − 2.17%, − 0.77%), − 2.17% change in HF (95%CI − 3.24%, − 1.10%), and − 1.52% change in LF (95%CI − 2.50%, − 0.54%), respectively. Overall, subgroup analysis suggested that short-term exposure to PM2.5 was associated with lower HRV levels in Asians, healthy population, and those aged ≥ 40 years. Conclusion Short-term exposure to PM2.5 was associated with decreased HRV levels. Future studies are warranted to clarity the exact mechanism of exposure to PM2.5 on the cardiovascular system through disturbance of autonomic nervous function.

scholarly journals Effect of short-term exposure to particulate air pollution on heart rate variability in normal-weight and obese adults

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Luyi Li ◽  
Dayu Hu ◽  
Wenlou Zhang ◽  
Liyan Cui ◽  
Xu Jia ◽  
...  
Keyword(s):  
Heart Rate ◽  
Air Pollution ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Normal Weight ◽  
High Frequency Power ◽  
Short Term ◽  
Particulate Air Pollution ◽  
Short Term Exposure ◽  
Frequency Power

Abstract Background The adverse effects of particulate air pollution on heart rate variability (HRV) have been reported. However, it remains unclear whether they differ by the weight status as well as between wake and sleep. Methods A repeated-measure study was conducted in 97 young adults in Beijing, China, and they were classified by body mass index (BMI) as normal-weight (BMI, 18.5–24.0 kg/m2) and obese (BMI ≥ 28.0 kg/m2) groups. Personal exposures to fine particulate matter (PM2.5) and black carbon (BC) were measured with portable exposure monitors, and the ambient PM2.5/BC concentrations were obtained from the fixed monitoring sites near the subjects’ residences. HRV and heart rate (HR) were monitored by 24-h Holter electrocardiography. The study period was divided into waking and sleeping hours according to time-activity diaries. Linear mixed-effects models were used to investigate the effects of PM2.5/BC on HRV and HR in both groups during wake and sleep. Results The effects of short-term exposure to PM2.5/BC on HRV were more pronounced among obese participants. In the normal-weight group, the positive association between personal PM2.5/BC exposure and high-frequency power (HF) as well as the ratio of low-frequency power to high-frequency power (LF/HF) was observed during wakefulness. In the obese group, personal PM2.5/BC exposure was negatively associated with HF but positively associated with LF/HF during wakefulness, whereas it was negatively correlated to total power and standard deviation of all NN intervals (SDNN) during sleep. An interquartile range (IQR) increase in BC at 2-h moving average was associated with 37.64% (95% confidence interval [CI]: 25.03, 51.51%) increases in LF/HF during wakefulness and associated with 6.28% (95% CI: − 17.26, 6.15%) decreases in SDNN during sleep in obese individuals, and the interaction terms between BC and obesity in LF/HF and SDNN were both statistically significant (p <  0.05). The results also suggested that the effects of PM2.5/BC exposure on several HRV indices and HR differed in magnitude or direction between wake and sleep. Conclusions Short-term exposure to PM2.5/BC is associated with HRV and HR, especially in obese individuals. The circadian rhythm of HRV should be considered in future studies when HRV is applied. Graphical abstract

Short-Term Exposure To Ozone Causes A Dose-Dependent Reduction In Heart-Rate Variability

2012 ◽  
Author(s):  
Mehrdad Arjomandi ◽  
Hofer Wong ◽  
Aneesh Donde ◽  
Karron Power ◽  
Nina Holland ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Short Term ◽  
Short Term Exposure ◽  
Dose Dependent

scholarly journals Effects of GLP-1 on counter-regulatory responses during hypoglycemia after GBP surgery

2019 ◽  
Vol 181 (2) ◽  
pp. 161-171 ◽  
Author(s):  
Kristina E Almby ◽  
Niclas Abrahamsson ◽  
Martin H Lundqvist ◽  
Ulf Hammar ◽  
Ketan Thombare ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Receptor Activation ◽  
Short Term ◽  
Parasympathetic Nerve ◽  
Short Term Exposure ◽  
Clamp Study

Objectives The aim of the study was to explore the role of GLP-1 receptor activation on the counter-regulation and symptoms of hypoglycemia in subjects who have undergone gastric bypass surgery (GBP). Design Experimental hyperinsulinemic–hypoglycemic clamp study. Methods Twelve post-GBP subjects participated in a randomized cross-over study with two hyperinsulinemic, hypoglycemic clamps (glucose nadir 2.7 mmol/L) performed on separate days with concomitant infusions of the GLP-1 analog exenatide or with saline, respectively. Continuous measurements of metabolites and counter-regulatory hormones as well as assessments of heart rate variability and symptoms of hypoglycemia were performed throughout the clamps. Results No effect of GLP-1 receptor activation on counter-regulatory hormones (glucagon, catecholamines, cortisol, GH) or glucose infusion rate was seen, but we found indications of a downregulation of the sympathetic relative to the parasympathetic nerve activity, as reflected in heart rate variability. No significant differences in symptom of hypoglycemia were observed. Conclusions/interpretation Short-term exposure to a GLP-1 receptor agonist does not seem to impact the counter-regulatory hormonal and metabolic responses in post-GBP subjects during hypoglycemic conditions, suggesting that the improvement in symptomatic hypoglycemia post-GBP seen following treatment with GLP-1 receptor agonists may be mediated by mechanism not directly involved in counter-regulation.

scholarly journals Short-Term Exposure to Ozone Does Not Impair Vascular Function or Affect Heart Rate Variability in Healthy Young Men

2013 ◽  
Vol 135 (2) ◽  
pp. 292-299 ◽  
Author(s):  
Stefan Barath ◽  
Jeremy P. Langrish ◽  
Magnus Lundbäck ◽  
Jenny A. Bosson ◽  
Colin Goudie ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Vascular Function ◽  
Young Men ◽  
Short Term ◽  
Short Term Exposure ◽  
Affect Heart Rate
Sign in / Sign up

Export Citation Format

Share Document